Homo sapiens ligase IV, DNA, ATP-dependent, mRNA (cDNA clone MGC:33819 - Nucleotide

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Expanding the phenotypic spectrum of LIG4 pathogenic variations: neuro-histopathological description of 4 fetuses with stenosis of the aqueduct. [Eur J Hum Genet. 2024]
Expanding the phenotypic spectrum of LIG4 pathogenic variations: neuro-histopathological description of 4 fetuses with stenosis of the aqueduct.
Nicolle R, Boutaud L, Loeuillet L, Talhi N, Grotto S, Bourgon N, Feresin A, Coussement A, Barrois M, Beaujard MP, et al. Eur J Hum Genet. 2024 May; 32(5):545-549. Epub 2024 Feb 13.
The Contribution of DNA Ligase 4 Polymorphisms to Colorectal Cancer. [In Vivo. 2024]
The Contribution of DNA Ligase 4 Polymorphisms to Colorectal Cancer.
Deng Y, Ke TW, Yueh TC, Chin YT, Wang YC, Hung YC, Mong MC, Yang YC, Wu WT, Chang WS, et al. In Vivo. 2024 Jan-Feb; 38(1):127-133.
Deficiency of ligase IV leads to reduced NHEJ, accumulation of DNA damage, and can sensitize cells to cancer therapeutics. [Genomics. 2023]
Deficiency of ligase IV leads to reduced NHEJ, accumulation of DNA damage, and can sensitize cells to cancer therapeutics.
Kumari N, Antil H, Kumari S, Raghavan SC. Genomics. 2023 Nov; 115(6):110731. Epub 2023 Oct 21.

RefSeq alternative splicing
See 12 reference mRNA sequence splice variants for the LIG4 gene.

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Nucleotide