U.S. flag

An official website of the United States government

Homo sapiens cytochrome P450 2D6 (CYP2D6) gene, CYP2D6*43 allele, complete cds

GenBank: DQ282154.1

FASTA Graphics PopSet 

LOCUS       DQ282154                6019 bp    DNA     linear   PRI 09-APR-2007
DEFINITION  Homo sapiens cytochrome P450 2D6 (CYP2D6) gene, CYP2D6*43 allele,
            complete cds.
ACCESSION   DQ282154
VERSION     DQ282154.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6019)
  AUTHORS   Koch,W.H., Nikoloff,D.M., Lu,W., Pan,R.M., deLeon,J. and
            Wedlund,P.J.
  TITLE     CYP2D6 Evolution and Allele Diversity Among Human Races
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6019)
  AUTHORS   Koch,W.H., Nikoloff,D.M., Lu,W., Pan,R.M., deLeon,J. and
            Wedlund,P.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2005) College of Pharmacy, University of
            Kentucky, 420 College of Pharmacy Building, Lexington, KT
            40536-0082, USA
FEATURES             Location/Qualifiers
     source          1..6019
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
     gene            1519..5897
                     /gene="CYP2D6"
                     /allele="CYP2D6*43"
     mRNA            join(1519..1786,2489..2660,3213..3365,3454..3614,
                     4048..4224,4415..4556,4764..4951,5406..5547,5646..5897)
                     /gene="CYP2D6"
                     /allele="CYP2D6*43"
     CDS             join(1607..1786,2489..2660,3213..3365,3454..3614,
                     4048..4224,4415..4556,4764..4951,5406..5547,5646..5824)
                     /gene="CYP2D6"
                     /allele="CYP2D6*43"
                     /codon_start=1
                     /product="cytochrome P450 2D6"
                     /protein_id="ABB77902.1"
                     /translation="MGLEALVPLAVIVAIFLLLVDLMHRHQRWAARYPPGPLPLPGLG
                     NLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRP
                     PVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACL
                     CAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESG
                     FLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFL
                     AEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQE
                     IDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKG
                     TTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLAR
                     MELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR"
     variation       1683
                     /gene="CYP2D6"
                     /note="compared to CYP2D6*1 allele of GenBank Accession
                     Number AY545216"
                     /replace="g"
     variation       1916
                     /gene="CYP2D6"
                     /note="compared to CYP2D6*1 allele of GenBank Accession
                     Number AY545216"
                     /replace="g"
ORIGIN      
        1 gcctggacaa cttggaagaa cccggtctct acaaaaaata caaaattagc tgggattggg
       61 tgcggtggct catgcctata atcccagcac tttgggagcc tgaggtgggt ggatcacctg
      121 aagtcaggag ttcaagacta gcctggccaa catggtgaaa ccctatctct actgaaaata
      181 caaaaagcta gacgtggtgg cacacacctg taatcccagc tacttaggag gctgaggcag
      241 gagaattgct tgaagcctag aggtgaaggt tgtagtgagc cgagattgca tcattgcaca
      301 atggagggga gccaccagcc tgggcaacaa gaggaaatct ccgtctccaa aaaaaaaaaa
      361 aaaaaaaaaa gaattaggct gggtggtgcc tgtagtccca gctacttggg aggcaggggg
      421 tccacttgat gtcgagactg cagtgagcca tgatcctgcc actgcactcc ggcctgggca
      481 acagagtgag accctgtcta aagaaaaaaa aaataaagca acatatcctg aacaaaggat
      541 cctccataac gttcccacca gatttctaat cagaaacatg gaggccagaa agcagtggag
      601 gaggacgacc ctcaggcagc ccgggaggat gttgtcacag gctggggcaa gggccttccg
      661 gctaccaact gggagctctg ggaacagccc tgttgcaaac aagaagccat agcccggcca
      721 gagcccagga atgtgggctg ggctgggagc agcctctgga caggagtggt cccatccagg
      781 aaacctccgg catggctggg aagtggggta cttggtgccg ggtctgtatg tgtgtgtgac
      841 tggtgtgtgt gagagagaat gtgtgcccta agtgtcagtg tgagtctgtg tatgtgtgaa
      901 tattgtcttt gtgtgggtga ttttctgcgt gtgtaatcgt gtccctgcaa gtgtgaacaa
      961 gtggacaagt gtctgggagt ggacaagaga tctgtgcacc atcaggtgtg tgcatagcgt
     1021 ctgtgcatgt caagagtgca aggtgaagtg aagggaccag gcccatgatg ccactcatca
     1081 tcaggagctc taaggcccca ggtaagtgcc agtgacagat aagggtgctg aaggtcactc
     1141 tggagtgggc aggtgggggt agggaaaggg caaggccatg ttctggagga ggggttgtga
     1201 ctacattagg gtgtatgagc ctagctggga ggtggatggc cgggtccact gaaaccctgg
     1261 ttatcccaga aggctttgca ggcttcagga gcttggagtg gggagagggg gtgacttctc
     1321 cgaccaggcc cctccaccgg cctaccctgg gtaagggcct ggagcaggaa gcaggggcaa
     1381 gaacctctgg agcagcccat acccgccctg gcctgactct gccactggca gcacagtcaa
     1441 cacagcaggt tcactcacag cagagggcaa aggccatcat cagctccctt tataagggaa
     1501 gggtcacgcg ctcggtgtgc tgagagtgtc ctgcctggtc ctctgtgcct ggtggggtgg
     1561 gggtgccagg tgtgtccaga ggagcccatt tggtagtgag gcaggtatgg ggctagaagc
     1621 actggtgccc ctggccgtga tagtggccat cttcctgctc ctggtggacc tgatgcaccg
     1681 gcaccaacgc tgggctgcac gctacccacc aggccccctg ccactgcccg ggctgggcaa
     1741 cctgctgcat gtggacttcc agaacacacc atactgcttc gaccaggtga gggaggaggt
     1801 cctggagggc ggcagaggtg ctgaggctcc cctaccagaa gcaaacatgg atggtgggtg
     1861 aaaccacagg ctggaccaga agccaggctg agaaggggaa gcaggtttgg gggacttcct
     1921 ggagaagggc atttatacat ggcatgaagg actggatttt ccaaaggcca aggaagagta
     1981 gggcaagggc ctggaggtgg agctggactt ggcagtgggc atgcaagccc attgggcaac
     2041 atatgttatg gagtacaaag tcccttctgc tgacaccaga aggaaaggcc ttgggaatgg
     2101 aagatgagtt agtcctgagt gccgtttaaa tcacgaaatc gaggatgaag ggggtgcagt
     2161 gacccggttc aaaccttttg cactgtgggt cctcgggcct cactgctcac cggcatggac
     2221 catcatctgg gaatgggatg ctaactgggg cctctcggca attttggtga ctcttgcaag
     2281 gtcatacctg ggtgacgcat ccaaactgag ttcctccatc acagaaggtg tgacccccac
     2341 ccccgcccca cgatcaggag gctgggtctc ctccttccac ctgctcactc ctggtagccc
     2401 cgggggtcgt ccaaggttca aataggacta ggacctgtag tctggggtga tcctggcttg
     2461 acaagaggcc ctgaccctcc ctctgcagtt gcggcgccgc ttcggggacg tgttcagcct
     2521 gcagctggcc tggacgccgg tggtcgtgct caatgggctg gcggccgtgc gcgaggcgct
     2581 ggtgacccac ggcgaggaca ccgccgaccg cccgcctgtg cccatcaccc agatcctggg
     2641 tttcgggccg cgttcccaag gcaagcagcg gtggggacag agacagattt ccgtgggacc
     2701 cgggtgggtg atgaccgtag tccgagctgg gcagagaggg cgcggggtcg tggacatgaa
     2761 acaggccagc gagtggggac agcgggccaa gaaaccacct gcactaggga ggtgtgagca
     2821 tggggacgag ggcggggctt gtgacgagtg ggcggggcca ctgccgagac ctggcaggag
     2881 cccaatgggt gaggctggcg catttcccag ctggaatccg gtgtcgaagt ggggggcggg
     2941 gaccgcacct gtgctgtaag ctcagtgtgg gtggcgcggg gcccgcgggg tcttccctga
     3001 gtgcaaaggc ggtcagggtg ggcagagacg aggtggggca aagccctgcc ccagccaagg
     3061 gagcaaggtg gatgcacaaa gagtgggccc tgtgaccagc tggacagagc cagggactgc
     3121 gggagaccag ggggagcata gggttggagt gggtggtgga tggtggggct aatgccttca
     3181 tggccacgcg cacgtgcccg tcccaccccc aggggtgttc ctggcgcgct atgggcccgc
     3241 gtggcgcgag cagaggcgct tctccgtgtc caccttgcgc aacttgggcc tgggcaagaa
     3301 gtcgctggag cagtgggtga ccgaggaggc cgcctgcctt tgtgccgcct tcgccaacca
     3361 ctccggtggg tgatgggcag aagggcacaa agcgggaact gggaaggcgg gggacgggga
     3421 aggcgacccc ttacccgcat ctcccacccc caggacgccc ctttcgcccc aacggtctct
     3481 tggacaaagc cgtgagcaac gtgatcgcct ccctcacctg cgggcgccgc ttcgagtacg
     3541 acgaccctcg cttcctcagg ctgctggacc tagctcagga gggactgaag gaggagtcgg
     3601 gctttctgcg cgaggtgcgg agcgagagac cgaggagtct ctgcagggcg agctcccgag
     3661 aggtgccggg gctggactgg ggcctcggaa gagcaggatt tgcatagatg ggtttgggaa
     3721 aggacattcc aggagacccc actgtaagaa gggcctggag gaggagggga catctcagac
     3781 atggtcgtgg gagaggtgtg cccgggtcag ggggcaccag gagaggccaa ggactctgta
     3841 cctcctatcc acgtcagaga tttcgatttt aggtttctcc tctgggcaag gagagagggt
     3901 ggaggctggc acttggggag ggacttggtg aggtcagtgg taaggacagg caggccctgg
     3961 gtctacctgg agatggctgg ggcctgagac ttgtccaggt gaacgcagag cacaggaggg
     4021 attgagaccc cgttctgtct ggtgtaggtg ctgaatgctg tccccgtcct cctgcatatc
     4081 ccagcgctgg ctggcaaggt cctacgcttc caaaaggctt tcctgaccca gctggatgag
     4141 ctgctaactg agcacaggat gacctgggac ccagcccagc ccccccgaga cctgactgag
     4201 gccttcctgg cagagatgga gaaggtgaga gtggctgcca cggtgggggg caagggtggt
     4261 gggttgagcg tcccaggagg aatgagggga ggctgggcaa aaggttggac cagtgcatca
     4321 cccggcgagc cgcatctggg ctgacaggtg cagaattgga ggtcatttgg gggctacccc
     4381 gttctgtccc gagtatgctc tcggccctgc tcaggccaag gggaaccctg agagcagctt
     4441 caatgatgag aacctgcgca tagtggtggc tgacctgttc tctgccggga tggtgaccac
     4501 ctcgaccacg ctggcctggg gcctcctgct catgatccta catccggatg tgcagcgtga
     4561 gcccatctgg gaaacagtgc aggggccgag ggaggaaggg tacaggcggg ggcccatgaa
     4621 ctttgctggg acacccgggg ctccaagcac aggcttgacc aggatcctgt aagcctgacc
     4681 tcctccaaca taggaggcaa gaaggagtgt cagggccgga ccccctgggt gctgacccat
     4741 tgtggggacg catgtctgtc caggccgtgt ccaacaggag atcgacgacg tgatagggca
     4801 ggtgcggcga ccagagatgg gtgaccaggc tcacatgccc tacaccactg ccgtgattca
     4861 tgaggtgcag cgctttgggg acatcgtccc cctgggtgtg acccatatga catcccgtga
     4921 catcgaagta cagggcttcc gcatccctaa ggtaggcctg gcgccctcct caccccagct
     4981 cagcaccagc acctggtgat agccccagca tggctactgc caggtgggcc cactctagga
     5041 accctggcca cctagtcctc aatgccacca cactgactgt ccccacttgg gtggggggtc
     5101 cagagtatag gcagggctgg cctgtccatc cagagccccc gtctagtggg gagacaaacc
     5161 aggacctgcc agaatgttgg aggacccaac gcctgcaggg agagggggca gtgtgggtgc
     5221 ctctgagagg tgtgactgcg ccctgctgtg gggtcggaga gggtactgtg gagcttctcg
     5281 ggcgcaggac tagttgacag agtccagctg tgtgccaggc agtgtgtgtc ccccgtgtgt
     5341 ttggtggcag gggtcccagc atcctagagt ccagtcccca ctctcaccct gcatctcctg
     5401 cccagggaac gacactcatc accaacctgt catcggtgct gaaggatgag gccgtctggg
     5461 agaagccctt ccgcttccac cccgaacact tcctggatgc ccagggccac tttgtgaagc
     5521 cggaggcctt cctgcctttc tcagcaggtg cctgtgggga gcccggctcc ctgtcccctt
     5581 ccgtggagtc ttgcaggggt atcacccagg agccaggctc actgacgccc ctcccctccc
     5641 cacaggccgc cgtgcatgcc tcggggagcc cctggcccgc atggagctct tcctcttctt
     5701 cacctccctg ctgcagcact tcagcttctc ggtgcccact ggacagcccc ggcccagcca
     5761 ccatggtgtc tttgctttcc tggtgagccc atccccctat gagctttgtg ctgtgccccg
     5821 ctagaatggg gtacctagtc cccagcctgc tccctagcca gaggctctaa tgtacaataa
     5881 agcaatgtgg tagttccaac tcgggtcccc tgctcacgcc ctcgttggga tcatcctcct
     5941 cagggcaacc ccacccctgc ctcattcctg cttaccccac cgcctggccg catttgagac
     6001 aggggtacgt tgaggctga
//
Feature
Display: FASTA GenBank Help
Details

Supplemental Content

Change region shown

Customize view

Reference sequence information

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
External link. Please review our privacy policy.