U.S. flag

An official website of the United States government

Homo sapiens cytochrome P450 2D6 (CYP2D6) gene, CYP2D6*45B allele, complete cds

GenBank: DQ282155.1

FASTA Graphics PopSet 

LOCUS       DQ282155                6018 bp    DNA     linear   PRI 09-APR-2007
DEFINITION  Homo sapiens cytochrome P450 2D6 (CYP2D6) gene, CYP2D6*45B allele,
            complete cds.
ACCESSION   DQ282155
VERSION     DQ282155.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6018)
  AUTHORS   Koch,W.H., Nikoloff,D.M., Lu,W., Pan,R.M., deLeon,J. and
            Wedlund,P.J.
  TITLE     CYP2D6 Evolution and Allele Diversity Among Human Races
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6018)
  AUTHORS   Koch,W.H., Nikoloff,D.M., Lu,W., Pan,R.M., deLeon,J. and
            Wedlund,P.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2005) College of Pharmacy, University of
            Kentucky, 420 College of Pharmacy Building, Lexington, KT
            40536-0082, USA
FEATURES             Location/Qualifiers
     source          1..6018
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
     variation       67
                     /note="compared to CYP2D6*1 allele of GenBank Accession
                     Number AY545216"
                     /replace="g"
     variation       312
                     /note="compared to CYP2D6*1 allele of GenBank Accession
                     Number AY545216"
                     /replace="g"
     variation       379
                     /note="compared to CYP2D6*1 allele of GenBank Accession
                     Number AY545216"
                     /replace="a"
     variation       874
                     /note="compared to CYP2D6*1 allele of GenBank Accession
                     Number AY545216"
                     /replace="c"
     variation       917^918
                     /note="compared to CYP2D6*1 allele of GenBank Accession
                     Number AY545216"
                     /replace="gtgt"
     gene            1522..5900
                     /gene="CYP2D6"
                     /allele="CYP2D6*45B"
     mRNA            join(1522..1789,2492..2663,3216..3368,3457..3617,
                     4051..4227,4418..4559,4767..4954,5409..5550,5649..5900)
                     /gene="CYP2D6"
                     /allele="CYP2D6*45B"
     CDS             join(1610..1789,2492..2663,3216..3368,3457..3617,
                     4051..4227,4418..4559,4767..4954,5409..5550,5649..5827)
                     /gene="CYP2D6"
                     /allele="CYP2D6*45B"
                     /codon_start=1
                     /product="cytochrome P450 2D6"
                     /protein_id="ABB77903.1"
                     /translation="MGLEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLG
                     NLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRP
                     PVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTKEAACL
                     CAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESG
                     FLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFL
                     AEMEKAKGNPESSFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQE
                     IDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKG
                     TTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLAR
                     MELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVTPSPYELCAVPR"
     variation       1919
                     /gene="CYP2D6"
                     /note="compared to CYP2D6*1 allele of GenBank Accession
                     Number AY545216"
                     /replace="g"
     variation       2354
                     /gene="CYP2D6"
                     /note="compared to CYP2D6*1 allele of GenBank Accession
                     Number AY545216"
                     /replace="c"
     variation       2451
                     /gene="CYP2D6"
                     /note="compared to CYP2D6*1 allele of GenBank Accession
                     Number AY545216"
                     /replace="t"
     variation       3271
                     /gene="CYP2D6"
                     /note="compared to CYP2D6*1 allele of GenBank Accession
                     Number AY545216"
                     /replace="g"
     variation       3326
                     /gene="CYP2D6"
                     /note="compared to CYP2D6*1 allele of GenBank Accession
                     Number AY545216"
                     /replace="g"
     variation       4185
                     /gene="CYP2D6"
                     /note="compared to CYP2D6*1 allele of GenBank Accession
                     Number AY545216"
                     /replace="c"
     variation       4271
                     /gene="CYP2D6"
                     /note="compared to CYP2D6*1 allele of GenBank Accession
                     Number AY545216"
                     /replace="g"
     variation       4460
                     /gene="CYP2D6"
                     /note="compared to CYP2D6*1 allele of GenBank Accession
                     Number AY545216"
                     /replace="c"
     variation       4864
                     /gene="CYP2D6"
                     /note="compared to CYP2D6*1 allele of GenBank Accession
                     Number AY545216"
                     /replace="t"
     variation       4994
                     /gene="CYP2D6"
                     /note="compared to CYP2D6*1 allele of GenBank Accession
                     Number AY545216"
                     /replace="a"
     variation       5194
                     /gene="CYP2D6"
                     /note="compared to CYP2D6*1 allele of GenBank Accession
                     Number AY545216"
                     /replace="g"
     variation       5400
                     /gene="CYP2D6"
                     /note="compared to CYP2D6*1 allele of GenBank Accession
                     Number AY545216"
                     /replace="c"
     variation       5790
                     /gene="CYP2D6"
                     /note="compared to CYP2D6*1 allele of GenBank Accession
                     Number AY545216"
                     /replace="g"
ORIGIN      
        1 ccagcctgga caacttggaa gaacccggtc tctacaaaaa atacaaaatt agctgggatt
       61 gggtgcagtg gctcatgcct ataatcccag cactttggga gcctgaggtg ggtggatcac
      121 ctgaagtcag gagttcaaga ctagcctggc caacatggtg aaaccctatc tctactgaaa
      181 atacaaaaag ctagacgtgg tggcacacac ctgtaatccc agctacttag gaggctgagg
      241 caggagaatt gcttgaagcc tagaggtgaa ggttgtagtg agccgagatt gcatcattgc
      301 acaatggagg gaagccacca gcctgggcaa caagaggaaa tctccgtctc caaaaaaaaa
      361 aaaaaaaaaa aaaaaaagga ttaggctggg tggtgcctgt agtcccagct acttgggagg
      421 cagggggtcc acttgatgtc gagactgcag tgagccatga tcctgccact gcactccggc
      481 ctgggcaaca gagtgagacc ctgtctaaag aaaaaaaaaa taaagcaaca tatcctgaac
      541 aaaggatcct ccataacgtt cccaccagat ttctaatcag aaacatggag gccagaaagc
      601 agtggaggag gacgaccctc aggcagcccg ggaggatgtt gtcacaggct ggggcaaggg
      661 ccttccggct accaactggg agctctggga acagccctgt tgcaaacaag aagccatagc
      721 ccggccagag cccaggaatg tgggctgggc tgggagcagc ctctggacag gagtggtccc
      781 atccaggaaa cctccggcat ggctgggaag tggggtactt ggtgccgggt ctgtatgtgt
      841 gtgtgactgg tgtgtgtgag agagaatgtg tgctctaagt gtcagtgtga gtctgtgtat
      901 gtgtgaatat tgtctttggg tgattttctg cgtgtgtaat cgtgtccctg caagtgtgaa
      961 caagtggaca agtgtctggg agtggacaag agatctgtgc accatcaggt gtgtgcatag
     1021 cgtctgtgca tgtcaagagt gcaaggtgaa gtgaagggac caggcccatg atgccactca
     1081 tcatcaggag ctctaaggcc ccaggtaagt gccagtgaca gataagggtg ctgaaggtca
     1141 ctctggagtg ggcaggtggg ggtagggaaa gggcaaggcc atgttctgga ggaggggttg
     1201 tgactacatt agggtgtatg agcctagctg ggaggtggat ggccgggtcc actgaaaccc
     1261 tggttatccc agaaggcttt gcaggcttca ggagcttgga gtggggagag ggggtgactt
     1321 ctccgaccag gcccctccac cggcctaccc tgggtaaggg cctggagcag gaagcagggg
     1381 caagaacctc tggagcagcc catacccgcc ctggcctgac tctgccactg gcagcacagt
     1441 caacacagca ggttcactca cagcagaggg caaaggccat catcagctcc ctttataagg
     1501 gaagggtcac gcgctcggtg tgctgagagt gtcctgcctg gtcctctgtg cctggtgggg
     1561 tgggggtgcc aggtgtgtcc agaggagccc atttggtagt gaggcaggta tggggctaga
     1621 agcactggtg cccctggccg tgatagtggc catcttcctg ctcctggtgg acctgatgca
     1681 ccggcgccaa cgctgggctg cacgctaccc accaggcccc ctgccactgc ccgggctggg
     1741 caacctgctg catgtggact tccagaacac accatactgc ttcgaccagg tgagggagga
     1801 ggtcctggag ggcggcagag gtgctgaggc tcccctacca gaagcaaaca tggatggtgg
     1861 gtgaaaccac aggctggacc agaagccagg ctgagaaggg gaagcaggtt tgggggactt
     1921 cctggagaag ggcatttata catggcatga aggactggat tttccaaagg ccaaggaaga
     1981 gtagggcaag ggcctggagg tggagctgga cttggcagtg ggcatgcaag cccattgggc
     2041 aacatatgtt atggagtaca aagtcccttc tgctgacacc agaaggaaag gccttgggaa
     2101 tggaagatga gttagtcctg agtgccgttt aaatcacgaa atcgaggatg aagggggtgc
     2161 agtgacccgg ttcaaacctt ttgcactgtg ggtcctcggg cctcactgct caccggcatg
     2221 gaccatcatc tgggaatggg atgctaactg gggcctctcg gcaattttgg tgactcttgc
     2281 aaggtcatac ctgggtgacg catccaaact gagttcctcc atcacagaag gtgtgacccc
     2341 cacccccgcc ccaggatcag gaggctgggt ctcctccttc cacctgctca ctcctggtag
     2401 ccccgggggt cgtccaaggt tcaaatagga ctaggacctg tagtctgggg ggatcctggc
     2461 ttgacaagag gccctgaccc tccctctgca gttgcggcgc cgcttcgggg acgtgttcag
     2521 cctgcagctg gcctggacgc cggtggtcgt gctcaatggg ctggcggccg tgcgcgaggc
     2581 gctggtgacc cacggcgagg acaccgccga ccgcccgcct gtgcccatca cccagatcct
     2641 gggtttcggg ccgcgttccc aaggcaagca gcggtgggga cagagacaga tttccgtggg
     2701 acccgggtgg gtgatgaccg tagtccgagc tgggcagaga gggcgcgggg tcgtggacat
     2761 gaaacaggcc agcgagtggg gacagcgggc caagaaacca cctgcactag ggaggtgtga
     2821 gcatggggac gagggcgggg cttgtgacga gtgggcgggg ccactgccga gacctggcag
     2881 gagcccaatg ggtgaggctg gcgcatttcc cagctggaat ccggtgtcga agtggggggc
     2941 ggggaccgca cctgtgctgt aagctcagtg tgggtggcgc ggggcccgcg gggtcttccc
     3001 tgagtgcaaa ggcggtcagg gtgggcagag acgaggtggg gcaaagccct gccccagcca
     3061 agggagcaag gtggatgcac aaagagtggg ccctgtgacc agctggacag agccagggac
     3121 tgcgggagac cagggggagc atagggttgg agtgggtggt ggatggtggg gctaatgcct
     3181 tcatggccac gcgcacgtgc ccgtcccacc cccaggggtg ttcctggcgc gctatgggcc
     3241 cgcgtggcgc gagcagaggc gcttctccgt ctccaccttg cgcaacttgg gcctgggcaa
     3301 gaagtcgctg gagcagtggg tgaccaagga ggccgcctgc ctttgtgccg ccttcgccaa
     3361 ccactccggt gggtgatggg cagaagggca caaagcggga actgggaagg cgggggacgg
     3421 ggaaggcgac cccttacccg catctcccac ccccaggacg cccctttcgc cccaacggtc
     3481 tcttggacaa agccgtgagc aacgtgatcg cctccctcac ctgcgggcgc cgcttcgagt
     3541 acgacgaccc tcgcttcctc aggctgctgg acctagctca ggagggactg aaggaggagt
     3601 cgggctttct gcgcgaggtg cggagcgaga gaccgaggag tctctgcagg gcgagctccc
     3661 gagaggtgcc ggggctggac tggggcctcg gaagagcagg atttgcatag atgggtttgg
     3721 gaaaggacat tccaggagac cccactgtaa gaagggcctg gaggaggagg ggacatctca
     3781 gacatggtcg tgggagaggt gtgcccgggt cagggggcac caggagaggc caaggactct
     3841 gtacctccta tccacgtcag agatttcgat tttaggtttc tcctctgggc aaggagagag
     3901 ggtggaggct ggcacttggg gagggacttg gtgaggtcag tggtaaggac aggcaggccc
     3961 tgggtctacc tggagatggc tggggcctga gacttgtcca ggtgaacgca gagcacagga
     4021 gggattgaga ccccgttctg tctggtgtag gtgctgaatg ctgtccccgt cctcctgcat
     4081 atcccagcgc tggctggcaa ggtcctacgc ttccaaaagg ctttcctgac ccagctggat
     4141 gagctgctaa ctgagcacag gatgacctgg gacccagccc agccaccccg agacctgact
     4201 gaggccttcc tggcagagat ggagaaggtg agagtggctg ccacggtggg gggcaagggt
     4261 ggtgggttga acgtcccagg aggaatgagg ggaggctggg caaaaggttg gaccagtgca
     4321 tcacccggcg agccgcatct gggctgacag gtgcagaatt ggaggtcatt tgggggctac
     4381 cccgttctgt cccgagtatg ctctcggccc tgctcaggcc aaggggaacc ctgagagcag
     4441 cttcaatgat gagaacctgt gcatagtggt ggctgacctg ttctctgccg ggatggtgac
     4501 cacctcgacc acgctggcct ggggcctcct gctcatgatc ctacatccgg atgtgcagcg
     4561 tgagcccatc tgggaaacag tgcaggggcc gagggaggaa gggtacaggc gggggcccat
     4621 gaactttgct gggacacccg gggctccaag cacaggcttg accaggatcc tgtaagcctg
     4681 acctcctcca acataggagg caagaaggag tgtcagggcc ggaccccctg ggtgctgacc
     4741 cattgtgggg acgcatgtct gtccaggccg tgtccaacag gagatcgacg acgtgatagg
     4801 gcaggtgcgg cgaccagaga tgggtgacca ggctcacatg ccctacacca ctgccgtgat
     4861 tcacgaggtg cagcgctttg gggacatcgt ccccctgggt gtgacccata tgacatcccg
     4921 tgacatcgaa gtacagggct tccgcatccc taaggtaggc ctggcgccct cctcacccca
     4981 gctcagcacc agcccctggt gatagcccca gcatggctac tgccaggtgg gcccactcta
     5041 ggaaccctgg ccacctagtc ctcaatgcca ccacactgac tgtccccact tgggtggggg
     5101 gtccagagta taggcagggc tggcctgtcc atccagagcc cccgtctagt ggggagacaa
     5161 accaggacct gccagaatgt tggaggaccc aacacctgca gggagagggg gcagtgtggg
     5221 tgcctctgag aggtgtgact gcgccctgct gtggggtcgg agagggtact gtggagcttc
     5281 tcgggcgcag gactagttga cagagtccag ctgtgtgcca ggcagtgtgt gtcccccgtg
     5341 tgtttggtgg caggggtccc agcatcctag agtccagtcc ccactctcac cctgcatctt
     5401 ctgcccaggg aacgacactc atcaccaacc tgtcatcggt gctgaaggat gaggccgtct
     5461 gggagaagcc cttccgcttc caccccgaac acttcctgga tgcccagggc cactttgtga
     5521 agccggaggc cttcctgcct ttctcagcag gtgcctgtgg ggagcccggc tccctgtccc
     5581 cttccgtgga gtcttgcagg ggtatcaccc aggagccagg ctcactgacg cccctcccct
     5641 ccccacaggc cgccgtgcat gcctcgggga gcccctggcc cgcatggagc tcttcctctt
     5701 cttcacctcc ctgctgcagc acttcagctt ctcggtgccc actggacagc cccggcccag
     5761 ccaccatggt gtctttgctt tcctggtgac cccatccccc tatgagcttt gtgctgtgcc
     5821 ccgctagaat ggggtaccta gtccccagcc tgctccctag ccagaggctc taatgtacaa
     5881 taaagcaatg tggtagttcc aactcgggtc ccctgctcac gccctcgttg ggatcatcct
     5941 cctcagggca accccacccc tgcctcattc ctgcttaccc caccgcctgg ccgcatttga
     6001 gacaggggta cgttgagg
//
Feature
Display: FASTA GenBank Help
Details

Supplemental Content

Change region shown

Customize view

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
External link. Please review our privacy policy.