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Human progesterone receptor mRNA, complete cds

GenBank: M15716.1

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LOCUS       HUMPGRR                 3014 bp    mRNA    linear   PRI 07-JAN-1995
DEFINITION  Human progesterone receptor mRNA, complete cds.
ACCESSION   M15716
VERSION     M15716.1
KEYWORDS    progesterone receptor.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3014)
  AUTHORS   Misrahi,M., Atger,M., d'Auriol,L., Loosfelt,H., Meriel,C.,
            Fridlansky,F., Guiochon-Mantel,A., Galibert,F. and Milgrom,E.
  TITLE     Complete amino acid sequence of the human progesterone receptor
            deduced from cloned cDNA
  JOURNAL   Biochem. Biophys. Res. Commun. 143 (2), 740-748 (1987)
   PUBMED   3551956
COMMENT     Original source text: Human breast cancer cell line T47-D, cDNA to
            mRNA, clones lambda-hPR[1-4].
            Computer-readable sequence for kindly provided by E.Milgrom,
            27-MAY-1987.
FEATURES             Location/Qualifiers
     source          1..3014
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /map="11q22-q23"
                     /cell_line="T47-D"
                     /tissue_type="breast cancer"
     gene            1..3014
                     /gene="PGR"
     CDS             176..2977
                     /gene="PGR"
                     /codon_start=1
                     /product="progesterone receptor"
                     /protein_id="AAA60081.1"
                     /db_xref="GDB:G00-119-493"
                     /translation="MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDT
                     LPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSS
                     PPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRV
                     LSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAA
                     VEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFS
                     APRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAG
                     AASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEE
                     GAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSS
                     ASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAA
                     PALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKI
                     CLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRL
                     RKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQ
                     LIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFR
                     NLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLC
                     LTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAI
                     GLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIA
                     AQLPKILAGMVKPLLFHKK"
ORIGIN      936 bp upstream of SstII site.
        1 ctgaccagcg ccgccctccc ccgcccccga cccaggaggt ggagatccct ccggtccagc
       61 cacattcaac acccactttc tcctccctct gcccctatat tcccgaaacc ccctcctcct
      121 tcccttttcc ctcctccctg gagacggggg aggagaaaag gggagtccag tcgtcatgac
      181 tgagctgaag gcaaagggtc cccgggctcc ccacgtggcg ggcggcccgc cctcccccga
      241 ggtcggatcc ccactgctgt gtcgcccagc cgcaggtccg ttcccgggga gccagacctc
      301 ggacaccttg cctgaagttt cggccatacc tatctccctg gacgggctac tcttccctcg
      361 gccctgccag ggacaggacc cctccgacga aaagacgcag gaccagcagt cgctgtcgga
      421 cgtggagggc gcatattcca gagctgaagc tacaaggggt gctggaggca gcagttctag
      481 tcccccagaa aaggacagcg gactgctgga cagtgtcttg gacactctgt tggcgccctc
      541 aggtcccggg cagagccaac ccagccctcc cgcctgcgag gtcaccagct cttggtgcct
      601 gtttggcccc gaacttcccg aagatccacc ggctgccccc gccacccagc gggtgttgtc
      661 cccgctcatg agccggtccg ggtgcaaggt tggagacagc tccgggacgg cagctgccca
      721 taaagtgctg ccccggggcc tgtcaccagc ccggcagctg ctgctcccgg cctctgagag
      781 ccctcactgg tccggggccc cagtgaagcc gtctccgcag gccgctgcgg tggaggttga
      841 ggaggaggat ggctctgagt ccgaggagtc tgcgggtccg cttctgaagg gcaaacctcg
      901 ggctctgggt ggcgcggcgg ctggaggagg agccgcggct gtcccgccgg gggcggcagc
      961 aggaggcgtc gccctggtcc ccaaggaaga ttcccgcttc tcagcgccca gggtcgccct
     1021 ggtggagcag gacgcgccga tggcgcccgg gcgctccccg ctggccacca cggtgatgga
     1081 tttcatccac gtgcctatcc tgcctctcaa tcacgcctta ttggcagccc gcactcggca
     1141 gctgctggaa gacgaaagtt acgacggcgg ggccggggct gccagcgcct ttgccccgcc
     1201 gcggagttca ccctgtgcct cgtccacccc ggtcgctgta ggcgacttcc ccgactgcgc
     1261 gtacccgccc gacgccgagc ccaaggacga cgcgtaccct ctctatagcg acttccagcc
     1321 gcccgctcta aagataaagg aggaggagga aggcgcggag gcctccgcgc gctccccgcg
     1381 ttcctacctt gtggccggtg ccaaccccgc agccttcccg gatttcccgt tggggccacc
     1441 gcccccgctg ccgccgcgag cgaccccatc cagacccggg gaagcggcgg tgacggccgc
     1501 acccgccagt gcctcagtct cgtctgcgtc ctcctcgggg tcgaccctgg agtgcatcct
     1561 gtacaaagcg gagggcgcgc cgccccagca gggcccgttc gcgccgccgc cctgcaaggc
     1621 gccgggcgcg agcggctgcc tgctcccgcg ggacggcctg ccctccacct ccgcctctgc
     1681 cgccgccgcc ggggcggccc ccgcgctcta ccctgcactc ggcctcaacg ggctcccgca
     1741 gctcggctac caggccgccg tgctcaagga gggcctgccg caggtctacc cgccctatct
     1801 caactacctg aggccggatt cagaagccag ccagagccca caatacagct tcgagtcatt
     1861 acctcagaag atttgtttaa tctgtgggga tgaagcatca ggctgtcatt atggtgtcct
     1921 tacctgtggg agctgtaagg tcttctttaa gagggcaatg gaagggcagc acaactactt
     1981 atgtgctgga agaaatgact gcatcgttga taaaatccgc agaaaaaact gcccagcatg
     2041 tcgccttaga aagtgctgtc aggctggcat ggtccttgga ggtcgaaaat ttaaaaagtt
     2101 caataaagtc agagttgtga gagcactgga tgctgttgct ctcccacagc cagtgggcgt
     2161 tccaaatgaa agccaagccc taagccagag attcactttt tcaccaggtc aagacataca
     2221 gttgattcca ccactgatca acctgttaat gagcattgaa ccagatgtga tctatgcagg
     2281 acatgacaac acaaaacctg acacctccag ttctttgctg acaagtctta atcaactagg
     2341 cgagaggcaa cttctttcag tagtcaagtg gtctaaatca ttgccaggtt ttcgaaactt
     2401 acatattgat gaccagataa ctctcattca gtattcttgg atgagcttaa tggtgtttgg
     2461 tctaggatgg agatcctaca aacacgtcag tgggcagatg ctgtattttg cacctgatct
     2521 aatactaaat gaacagcgga tgaaagaatc atcattctat tcattatgcc ttaccatgtg
     2581 gcagatccca caggagtttg tcaagcttca agttagccaa gaagagttcc tctgtatgaa
     2641 agtattgtta cttcttaata caattccttt ggaagggcta cgaagtcaaa cccagtttga
     2701 ggagatgagg tcaagctaca ttagagagct catcaaggca attggtttga ggcaaaaagg
     2761 agttgtgtcg agctcacagc gtttctatca acttacaaaa cttcttgata acttgcatga
     2821 tcttgtcaaa caacttcatc tgtactgctt gaatacattt atccagtccc gggcactgag
     2881 tgttgaattt ccagaaatga tgtctgaagt tattgctgca caattaccca agatattggc
     2941 agggatggtg aaaccccttc tctttcataa aaagtgaatg tcatcttttt cttttaaaga
     3001 attaaatttt gtgg
//
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