Homo sapiens ketohexokinase (KHK), transcript variant a, mRNA

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Fructose induced KHK-C can increase ER stress independent of its effect on lipogenesis to drive liver disease in diet-induced and genetic models of NAFLD. [Metabolism. 2023]
Fructose induced KHK-C can increase ER stress independent of its effect on lipogenesis to drive liver disease in diet-induced and genetic models of NAFLD.
Park SH, Helsley RN, Fadhul T, Willoughby JLS, Noetzli L, Tu HC, Solheim MH, Fujisaka S, Pan H, Dreyfuss JM, et al. Metabolism. 2023 Aug; 145:155591. Epub 2023 May 23.
GLUT5-KHK axis-mediated fructose metabolism drives proliferation and chemotherapy resistance of colorectal cancer. [Cancer Lett. 2022]
GLUT5-KHK axis-mediated fructose metabolism drives proliferation and chemotherapy resistance of colorectal cancer.
Shen Z, Li Z, Liu Y, Li Y, Feng X, Zhan Y, Lin M, Fang C, Fang Y, Deng H. Cancer Lett. 2022 May 28; 534:215617. Epub 2022 Mar 4.
USP36 promotes tumor growth of non-small cell lung cancer via increasing KHK-A expression by regulating c-MYC-hnRNPH1/H2 axis. [Hum Cell. 2022]
USP36 promotes tumor growth of non-small cell lung cancer via increasing KHK-A expression by regulating c-MYC-hnRNPH1/H2 axis.
Deng Q, Wu M, Deng J. Hum Cell. 2022 Mar; 35(2):694-704. Epub 2022 Feb 8.

RefSeq alternative splicing
See 26 reference mRNA sequence splice variants for the KHK gene.
RefSeq protein product
See the reference protein sequence for ketohexokinase isoform a (NP_000212.1).

Protein
Protein sequence from Nucleotide coding region
PubMed
PubMed articles cited by Nucleotide sequence record
Taxonomy
Taxonomy sequences associated with Nucleotide record
Annotated Genomic
Genomic sequence records that have the current RNA records as annotated features marking the exons of genes.
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Functional Class
Functional class of the sequence domain architecture
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OMIM
OMIM records associated with Nucleotide sequence
PubMed (RefSeq)
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PubMed (Weighted)
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Nucleotide