LOCUS NM_001127553 1054 bp mRNA linear ROD 05-APR-2023
DEFINITION Rattus norvegicus ubiquinol-cytochrome c reductase binding protein
(Uqcrb), mRNA.
ACCESSION NM_001127553 XM_001057294 XM_343225
VERSION NM_001127553.2
KEYWORDS RefSeq; RefSeq Select.
SOURCE Rattus norvegicus (Norway rat)
ORGANISM Rattus norvegicus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
REFERENCE 1 (bases 1 to 1054)
AUTHORS Guo R, Zong S, Wu M, Gu J and Yang M.
TITLE Architecture of Human Mitochondrial Respiratory Megacomplex
I2III2IV2
JOURNAL Cell 170 (6), 1247-1257 (2017)
PUBMED 28844695
REFERENCE 2 (bases 1 to 1054)
AUTHORS Henningsen K, Palmfeldt J, Christiansen S, Baiges I, Bak S, Jensen
ON, Gregersen N and Wiborg O.
TITLE Candidate hippocampal biomarkers of susceptibility and resilience
to stress in a rat model of depression
JOURNAL Mol Cell Proteomics 11 (7), M111.016428 (2012)
PUBMED 22311638
REFERENCE 3 (bases 1 to 1054)
AUTHORS Schilling B, Murray J, Yoo CB, Row RH, Cusack MP, Capaldi RA and
Gibson BW.
TITLE Proteomic analysis of succinate dehydrogenase and
ubiquinol-cytochrome c reductase (Complex II and III) isolated by
immunoprecipitation from bovine and mouse heart mitochondria
JOURNAL Biochim Biophys Acta 1762 (2), 213-222 (2006)
PUBMED 16120479
REFERENCE 4 (bases 1 to 1054)
AUTHORS Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl
E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES and
Mann M.
TITLE Integrated analysis of protein composition, tissue diversity, and
gene regulation in mouse mitochondria
JOURNAL Cell 115 (5), 629-640 (2003)
PUBMED 14651853
REFERENCE 5 (bases 1 to 1054)
AUTHORS Da Cruz S, Xenarios I, Langridge J, Vilbois F, Parone PA and
Martinou JC.
TITLE Proteomic analysis of the mouse liver mitochondrial inner membrane
JOURNAL J Biol Chem 278 (42), 41566-41571 (2003)
PUBMED 12865426
REFERENCE 6 (bases 1 to 1054)
AUTHORS Haut S, Brivet M, Touati G, Rustin P, Lebon S, Garcia-Cazorla A,
Saudubray JM, Boutron A, Legrand A and Slama A.
TITLE A deletion in the human QP-C gene causes a complex III deficiency
resulting in hypoglycaemia and lactic acidosis
JOURNAL Hum Genet 113 (2), 118-122 (2003)
PUBMED 12709789
REFERENCE 7 (bases 1 to 1054)
AUTHORS Sun G, Kinter MT and Anderson VE.
TITLE Mass spectrometric characterization of mitochondrial electron
transport complexes: subunits of the rat heart ubiquinol-cytochrome
c reductase
JOURNAL J Mass Spectrom 38 (5), 531-539 (2003)
PUBMED 12794875
REFERENCE 8 (bases 1 to 1054)
AUTHORS Nishikimi,M., Shimomura,Y. and Ozawa,T.
TITLE Cell-free synthesis of ubiquinone-binding protein of mitochondrial
cytochrome bc1 complex
JOURNAL Biochem Biophys Res Commun 138 (3), 1291-1297 (1986)
PUBMED 3019339
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
CB783276.1, BC166882.1, AW918593.1 and AI556015.1.
On Sep 6, 2008 this sequence version replaced NM_001127553.1.
##Evidence-Data-START##
Transcript exon combination :: CB783276.1, BP482576.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
SAMN06621351, SAMN11044071
[ECO:0000348]
##Evidence-Data-END##
##RefSeq-Attributes-START##
gene product(s) localized to mito. :: inferred from homology
RefSeq Select criteria :: based on single
protein-coding transcript
##RefSeq-Attributes-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-15 CB783276.1 1-15
16-490 BC166882.1 1-475
491-1031 AW918593.1 103-643
1032-1054 AI556015.1 1-23 c
FEATURES Location/Qualifiers
source 1..1054
/organism="Rattus norvegicus"
/mol_type="mRNA"
/strain="Sprague-Dawley"
/db_xref="taxon:10116"
/chromosome="7"
/map="7q22"
gene 1..1054
/gene="Uqcrb"
/gene_synonym="Uqcrbl"
/note="ubiquinol-cytochrome c reductase binding protein"
/db_xref="GeneID:362897"
/db_xref="RGD:1311971"
exon 1..42
/gene="Uqcrb"
/gene_synonym="Uqcrbl"
/inference="alignment:Splign:2.1.0"
misc_feature 15..17
/gene="Uqcrb"
/gene_synonym="Uqcrbl"
/note="upstream in-frame stop codon"
CDS 24..359
/gene="Uqcrb"
/gene_synonym="Uqcrbl"
/EC_number="7.1.1.8"
/codon_start=1
/product="cytochrome b-c1 complex subunit 7"
/protein_id="NP_001121025.1"
/db_xref="GeneID:362897"
/db_xref="RGD:1311971"
/translation="MAGRPAVAASSKWLDGFRKWYYNAAGFNKLGLMRDDTMHETEDV
KEAIRRLPENLYNDRMFRIKRALDLSMRHQILPKDQWTKYEEDKFYLEPYLKEVIRER
KEREEWAKK"
exon 43..114
/gene="Uqcrb"
/gene_synonym="Uqcrbl"
/inference="alignment:Splign:2.1.0"
exon 115..281
/gene="Uqcrb"
/gene_synonym="Uqcrbl"
/inference="alignment:Splign:2.1.0"
exon 282..1042
/gene="Uqcrb"
/gene_synonym="Uqcrbl"
/inference="alignment:Splign:2.1.0"
ORIGIN
1 cagctctcta ctcttaggtc aaaatggcgg gccgacctgc agttgcagca tcaagcaagt
61 ggctggatgg tttccggaag tggtattata atgcagcggg cttcaataaa ctggggttaa
121 tgcgagatga cacaatgcat gaaactgaag atgtaaaaga agccataaga aggctgcctg
181 agaaccttta taatgacaga atgtttcgaa ttaagagagc cctagacctg tctatgcggc
241 atcagatctt gcctaaggat cagtggacaa aatatgagga ggacaaattc taccttgaac
301 cctatctgaa agaggttatt cgggaaagaa aggagagaga agagtgggcg aagaagtgat
361 cgtgtagtta agatctgtgg gtgcgcctgg tctcacccta ttttatgaca ttgtttcaac
421 ctgaatcaca acttaagaat catttgctct acacatgcct cactttaaat aaatgtctat
481 tataaccgtt gttggactat ttgaatccaa ttcaaacttt tactctcata attactatta
541 tcatttttat gacacaaatt ttttccagat ttctaagata tttttagttg ctgcttaact
601 ggagatgaca ggagctgctt taatcatctc ttcatggcta tataactatc cagcttactg
661 aaagatgcag cactttatac aagctgaata gtaggcttta gattcccttt ctgggctcct
721 gggaagtcat agcaaggcct gtacaggtgt gagatgaggg attaggcaac cagcactgaa
781 cagttgggcc atcagctttc agagtgactg atggaaggaa gggaacattt accccaggtt
841 agttacccag gacccgagac acagcctttc agaacattgc tctctaccta gatttatttt
901 gcatttagga aaagtctgta ttccattatg ggcttatgta acttacctat gtatgtgcag
961 gtgcatgtgc tcctatgcta atcagtaatg aataaataag taataaatct ggcatgagga
1021 aaacaacaga gaaaaacaca aaaaaaaaaa aaaa
//