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Rattus norvegicus ubiquinol-cytochrome c reductase binding protein (Uqcrb), mRNA

NCBI Reference Sequence: NM_001127553.2

FASTA Graphics 

LOCUS       NM_001127553            1054 bp    mRNA    linear   ROD 05-APR-2023
DEFINITION  Rattus norvegicus ubiquinol-cytochrome c reductase binding protein
            (Uqcrb), mRNA.
ACCESSION   NM_001127553 XM_001057294 XM_343225
VERSION     NM_001127553.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1054)
  AUTHORS   Guo R, Zong S, Wu M, Gu J and Yang M.
  TITLE     Architecture of Human Mitochondrial Respiratory Megacomplex
            I2III2IV2
  JOURNAL   Cell 170 (6), 1247-1257 (2017)
   PUBMED   28844695
REFERENCE   2  (bases 1 to 1054)
  AUTHORS   Henningsen K, Palmfeldt J, Christiansen S, Baiges I, Bak S, Jensen
            ON, Gregersen N and Wiborg O.
  TITLE     Candidate hippocampal biomarkers of susceptibility and resilience
            to stress in a rat model of depression
  JOURNAL   Mol Cell Proteomics 11 (7), M111.016428 (2012)
   PUBMED   22311638
REFERENCE   3  (bases 1 to 1054)
  AUTHORS   Schilling B, Murray J, Yoo CB, Row RH, Cusack MP, Capaldi RA and
            Gibson BW.
  TITLE     Proteomic analysis of succinate dehydrogenase and
            ubiquinol-cytochrome c reductase (Complex II and III) isolated by
            immunoprecipitation from bovine and mouse heart mitochondria
  JOURNAL   Biochim Biophys Acta 1762 (2), 213-222 (2006)
   PUBMED   16120479
REFERENCE   4  (bases 1 to 1054)
  AUTHORS   Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl
            E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES and
            Mann M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   5  (bases 1 to 1054)
  AUTHORS   Da Cruz S, Xenarios I, Langridge J, Vilbois F, Parone PA and
            Martinou JC.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
REFERENCE   6  (bases 1 to 1054)
  AUTHORS   Haut S, Brivet M, Touati G, Rustin P, Lebon S, Garcia-Cazorla A,
            Saudubray JM, Boutron A, Legrand A and Slama A.
  TITLE     A deletion in the human QP-C gene causes a complex III deficiency
            resulting in hypoglycaemia and lactic acidosis
  JOURNAL   Hum Genet 113 (2), 118-122 (2003)
   PUBMED   12709789
REFERENCE   7  (bases 1 to 1054)
  AUTHORS   Sun G, Kinter MT and Anderson VE.
  TITLE     Mass spectrometric characterization of mitochondrial electron
            transport complexes: subunits of the rat heart ubiquinol-cytochrome
            c reductase
  JOURNAL   J Mass Spectrom 38 (5), 531-539 (2003)
   PUBMED   12794875
REFERENCE   8  (bases 1 to 1054)
  AUTHORS   Nishikimi,M., Shimomura,Y. and Ozawa,T.
  TITLE     Cell-free synthesis of ubiquinone-binding protein of mitochondrial
            cytochrome bc1 complex
  JOURNAL   Biochem Biophys Res Commun 138 (3), 1291-1297 (1986)
   PUBMED   3019339
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB783276.1, BC166882.1, AW918593.1 and AI556015.1.
            
            On Sep 6, 2008 this sequence version replaced NM_001127553.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB783276.1, BP482576.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06621351, SAMN11044071
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                CB783276.1         1-15
            16-490              BC166882.1         1-475
            491-1031            AW918593.1         103-643
            1032-1054           AI556015.1         1-23                c
FEATURES             Location/Qualifiers
     source          1..1054
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q22"
     gene            1..1054
                     /gene="Uqcrb"
                     /gene_synonym="Uqcrbl"
                     /note="ubiquinol-cytochrome c reductase binding protein"
                     /db_xref="GeneID:362897"
                     /db_xref="RGD:1311971"
     exon            1..42
                     /gene="Uqcrb"
                     /gene_synonym="Uqcrbl"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    15..17
                     /gene="Uqcrb"
                     /gene_synonym="Uqcrbl"
                     /note="upstream in-frame stop codon"
     CDS             24..359
                     /gene="Uqcrb"
                     /gene_synonym="Uqcrbl"
                     /EC_number="7.1.1.8"
                     /codon_start=1
                     /product="cytochrome b-c1 complex subunit 7"
                     /protein_id="NP_001121025.1"
                     /db_xref="GeneID:362897"
                     /db_xref="RGD:1311971"
                     /translation="MAGRPAVAASSKWLDGFRKWYYNAAGFNKLGLMRDDTMHETEDV
                     KEAIRRLPENLYNDRMFRIKRALDLSMRHQILPKDQWTKYEEDKFYLEPYLKEVIRER
                     KEREEWAKK"
     exon            43..114
                     /gene="Uqcrb"
                     /gene_synonym="Uqcrbl"
                     /inference="alignment:Splign:2.1.0"
     exon            115..281
                     /gene="Uqcrb"
                     /gene_synonym="Uqcrbl"
                     /inference="alignment:Splign:2.1.0"
     exon            282..1042
                     /gene="Uqcrb"
                     /gene_synonym="Uqcrbl"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagctctcta ctcttaggtc aaaatggcgg gccgacctgc agttgcagca tcaagcaagt
       61 ggctggatgg tttccggaag tggtattata atgcagcggg cttcaataaa ctggggttaa
      121 tgcgagatga cacaatgcat gaaactgaag atgtaaaaga agccataaga aggctgcctg
      181 agaaccttta taatgacaga atgtttcgaa ttaagagagc cctagacctg tctatgcggc
      241 atcagatctt gcctaaggat cagtggacaa aatatgagga ggacaaattc taccttgaac
      301 cctatctgaa agaggttatt cgggaaagaa aggagagaga agagtgggcg aagaagtgat
      361 cgtgtagtta agatctgtgg gtgcgcctgg tctcacccta ttttatgaca ttgtttcaac
      421 ctgaatcaca acttaagaat catttgctct acacatgcct cactttaaat aaatgtctat
      481 tataaccgtt gttggactat ttgaatccaa ttcaaacttt tactctcata attactatta
      541 tcatttttat gacacaaatt ttttccagat ttctaagata tttttagttg ctgcttaact
      601 ggagatgaca ggagctgctt taatcatctc ttcatggcta tataactatc cagcttactg
      661 aaagatgcag cactttatac aagctgaata gtaggcttta gattcccttt ctgggctcct
      721 gggaagtcat agcaaggcct gtacaggtgt gagatgaggg attaggcaac cagcactgaa
      781 cagttgggcc atcagctttc agagtgactg atggaaggaa gggaacattt accccaggtt
      841 agttacccag gacccgagac acagcctttc agaacattgc tctctaccta gatttatttt
      901 gcatttagga aaagtctgta ttccattatg ggcttatgta acttacctat gtatgtgcag
      961 gtgcatgtgc tcctatgcta atcagtaatg aataaataag taataaatct ggcatgagga
     1021 aaacaacaga gaaaaacaca aaaaaaaaaa aaaa
//
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Reference sequence information

  • RefSeq protein product
    See the reference protein sequence for cytochrome b-c1 complex subunit 7 (NP_001121025.1).

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