LOCUS NM_001170289 7372 bp mRNA linear INV 26-DEC-2023
DEFINITION Drosophila melanogaster papilin, transcript variant C (Ppn), mRNA.
ACCESSION NM_001170289
VERSION NM_001170289.2
DBLINK BioProject: PRJNA164
BioSample: SAMN02803731
KEYWORDS RefSeq.
SOURCE Drosophila melanogaster (fruit fly)
ORGANISM Drosophila melanogaster
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
REFERENCE 1 (bases 1 to 7372)
AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St
Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K.,
Strelets,V., Russo,S.M. and Gelbart,W.M.
CONSRTM FlyBase Consortium
TITLE Gene Model Annotations for Drosophila melanogaster: Impact of
High-Throughput Data
JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015)
PUBMED 26109357
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 7372)
AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St
Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B.,
Russo,S.M. and Gelbart,W.M.
CONSRTM FlyBase Consortium
TITLE Gene Model Annotations for Drosophila melanogaster: The
Rule-Benders
JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015)
PUBMED 26109356
REMARK Publication Status: Online-Only
REFERENCE 3 (bases 1 to 7372)
AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I.,
Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R.,
Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G.,
Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N.,
Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A.,
Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E.
TITLE The Release 6 reference sequence of the Drosophila melanogaster
genome
JOURNAL Genome Res 25 (3), 445-458 (2015)
PUBMED 25589440
REFERENCE 4 (bases 1 to 7372)
AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M.,
Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F.,
Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E.
TITLE Sequence finishing and mapping of Drosophila melanogaster
heterochromatin
JOURNAL Science 316 (5831), 1625-1628 (2007)
PUBMED 17569867
REFERENCE 5 (bases 1 to 7372)
AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H.
TITLE The Release 5.1 annotation of Drosophila melanogaster
heterochromatin
JOURNAL Science 316 (5831), 1586-1591 (2007)
PUBMED 17569856
REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325]
REFERENCE 6 (bases 1 to 7372)
AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D.,
Ashburner,M. and Anxolabehere,D.
TITLE Combined evidence annotation of transposable elements in genome
sequences
JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005)
PUBMED 16110336
REFERENCE 7 (bases 1 to 7372)
AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A.,
Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A.,
Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W.,
Celniker,S.E., Rubin,G.M. and Karpen,G.H.
TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun
assembly
JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002)
PUBMED 12537574
REFERENCE 8 (bases 1 to 7372)
AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J.,
Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E.,
Rubin,G.M., Ashburner,M. and Celniker,S.E.
TITLE The transposable elements of the Drosophila melanogaster
euchromatin: a genomics perspective
JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002)
PUBMED 12537573
REFERENCE 9 (bases 1 to 7372)
AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S.,
Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E.,
Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L.,
Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D.,
Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J.,
Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M.,
Rubin,G.M. and Lewis,S.E.
TITLE Annotation of the Drosophila melanogaster euchromatic genome: a
systematic review
JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002)
PUBMED 12537572
REFERENCE 10 (bases 1 to 7372)
AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W.,
Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E.,
Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M.,
Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S.,
Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M.,
Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W.,
Gibbs,R.A. and Rubin,G.M.
TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila
melanogaster euchromatic genome sequence
JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002)
PUBMED 12537568
REFERENCE 11 (bases 1 to 7372)
AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D.,
Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F.,
George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N.,
Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X.,
Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D.,
Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L.,
Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D.,
Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M.,
Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S.,
Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P.,
Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A.,
Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B.,
Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I.,
Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S.,
Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C.,
Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S.,
Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z.,
Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J.,
Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J.,
Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z.,
Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C.,
Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A.,
Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C.,
McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C.,
Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L.,
Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K.,
Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S.,
Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K.,
Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I.,
Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C.,
Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R.,
Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A.,
Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT,
Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F.,
Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H.,
Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O.,
Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C.
TITLE The genome sequence of Drosophila melanogaster
JOURNAL Science 287 (5461), 2185-2195 (2000)
PUBMED 10731132
REFERENCE 12 (bases 1 to 7372)
AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R.,
Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R.,
Smith,E., Yu,C. and Rubin,G.
CONSRTM Berkeley Drosophila Genome Project
TITLE Drosophila melanogaster release 4 sequence
JOURNAL Unpublished
REFERENCE 13 (bases 1 to 7372)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 14 (bases 1 to 7372)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 15 (bases 1 to 7372)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 16 (bases 1 to 7372)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 17 (bases 1 to 7372)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 18 (bases 1 to 7372)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 19 (bases 1 to 7372)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 20 (bases 1 to 7372)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 21 (bases 1 to 7372)
AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R.,
Park,S., Svirskas,R. and Karpen,G.
TITLE Direct Submission
JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project,
Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne
Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA
REMARK Direct Submission
REFERENCE 22 (bases 1 to 7372)
AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S.,
Svirskas,R. and Rubin,G.
TITLE Direct Submission
JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project,
Lawrence Berkeley National Laboratory, One Cyclotron Road, MS
64-121, Berkeley, CA 94720, USA
REMARK Direct Submission
REFERENCE 23 (bases 1 to 7372)
AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H.
CONSRTM Drosophila Heterochromatin Genome Project
TITLE Direct Submission
JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project,
Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron
Road, Mailstop 64-121, Berkeley, CA 94720, USA
REFERENCE 24 (bases 1 to 7372)
AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J.
TITLE Direct Submission
JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive,
Rockville, MD 20850, USA
COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This
record is derived from an annotated genomic sequence (NT_033777).
On Jan 16, 2013 this sequence version replaced NM_001170289.1.
##Genome-Annotation-Data-START##
Annotation Provider :: FlyBase
Annotation Status :: Full annotation
Annotation Version :: Release 6.54
URL :: http://flybase.org
##Genome-Annotation-Data-END##
FEATURES Location/Qualifiers
source 1..7372
/organism="Drosophila melanogaster"
/mol_type="mRNA"
/db_xref="taxon:7227"
/chromosome="3R"
/genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2]
bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]"
gene 1..7372
/gene="Ppn"
/locus_tag="Dmel_CG33103"
/gene_synonym="CG1540; CG18436; CG33103; CT3186; CT41988;
Dmel\CG33103; ppl; ppn"
/note="Papilin"
/map="98D3-98D4"
/db_xref="FLYBASE:FBgn0003137"
/db_xref="GeneID:43872"
CDS 384..6908
/gene="Ppn"
/locus_tag="Dmel_CG33103"
/gene_synonym="CG1540; CG18436; CG33103; CT3186; CT41988;
Dmel\CG33103; ppl; ppn"
/note="CG33103 gene product from transcript CG33103-RC;
CG33103-PC; Ppn-PC; lacunin-like; papilin precursor"
/codon_start=1
/product="papilin, isoform C"
/protein_id="NP_001163760.1"
/db_xref="FLYBASE:FBpp0289566"
/db_xref="GeneID:43872"
/db_xref="FLYBASE:FBgn0003137"
/translation="MDLSRRLCSTALVAFIVLASIHDSQSRFPGLRQKRQYGANMYLP
ESSVTPGGEGNDPDEWTPWSSPSDCSRTCGGGVSYQTRECLRRDDRGEAVCSGGSRRY
FSCNTQDCPEEESDFRAQQCSRFDRQQFDGVFYEWVPYTNAPNPCELNCMPKGERFYY
RQREKVVDGTRCNDKDLDVCVNGECMPVGCDMMLGSDAKEDKCRKCGGDGSTCKTIRN
TITTKDLAPGYNDLLLLPEGATNIRIEETVPSSNYLACRNHSGHYYLNGDWRIDFPRP
MFFANSWWNYQRKPMGFAAPDQLTCSGPISESLFIVMLVQEKNISLDYEYSIPESLSH
SQQDTHTWTHHQFNACSASCGGGSQSRKVTCNNRITLAEVNPSLCDQKSKPVEEQACG
TEPCAPHWVEGEWSKCSKGCGSDGFQNRSITCERISSSGEHTVEEDAVCLKEVGNKPA
TKQECNRDVKNCPKYHLGPWTPCDKLCGDGKQTRKVTCFIEENGHKRVLPEEDCVEEK
PETEKSCLLTPCEGVDWIISQWSGCNACGQNTETRTAICGNKEGKVYPEEFCEPEVPT
LSRPCKSPKCEAQWFSSEWSKCSAPCGKGVKSRIVICGEFDGKTVTPADDDSKCNKET
KPESEQDCEGEEKVCPGEWFTGPWGKCSKPCGGGERVREVLCLSNGTKSVNCDEEKVE
PLSEKCNSEACTEDEILPLTSTDKPIEDDEEDCDEDGIELISDGLSDDEKSEDVIDLE
GTAKTETTPEAEDLMQSDSPTPYDEFESTGTTFEGSGYDSESTTDSGISTEGSGDDEE
TSEASTDLSSSTDSGSTSSDSTSSDSSSSISSDATSEAPASSVSDSSDSTDASTETTG
VSDDSTDVSSSTEASASESTDVSGASDSTGSTNASDSTPESSTEASSSTDDSTDSSDN
SSNVSESSTEASSSSVSDSNDSSDGSTDGVSSTTENSSDSTSDATSDSTASSDSTDST
SDQTTETTPESSTDSTESSTLDASSTTDASSTSESSSESSTDGSSTTSNSASSETTGL
SSDGSTTDATTAASDNTDITTDGSTDESTDGSSNASTEGSTEGASEDTTISTESSGST
ESTDAIASDGSTTEGSTVEDLSSSTSSDVTSDSTITDSSPSTEVSGSTDSSSSTDGSS
TDASSTEASSTDVTESTDSTVSGGTSDTTESGPTEESTTEGSTESTTEGSTDSTQSTD
LDSTTSDIWSTSDKDDESESSTPYSFDSEVTKSKPRKCKPKKSTCAKSEYGCCPDGKS
TPKGPFDEGCPIAKTCADTKYGCCLDGVSPAKGKNNKGCPKSQCAETLFGCCPDKFTA
ADGENDEGCPETTTVPPTTTTEETQPETTTEIEGSGQDSTTSEPDTKKSCSFSEFGCC
PDAETSAKGPDFEGCGLASPVAKGCAESENGCCPDGQTPASGPNGEGCSGCTRERFGC
CPDSQTPAHGPNKEGCCLDTQFGCCPDNILAARGPNNEGCECHYTPYGCCPDNKSAAT
GYNQEGCACETTQYGCCPDKITAAKGPKHEGCPCETTQFGCCPDGLTFAKGPHHHGCH
CTQTEFKCCDDEKTPAKGPNGDGCTCVESKFGCCPDGVTKATDEKFGGCENVQEPPQK
ACGLPKETGTCNNYSVKYYFDTSYGGCARFWYGGCDGNDNRFESEAECKDTCQDYTGK
HVCLLPKSAGPCTGFTKKWYFDVDRNRCEEFQYGGCYGTNNRFDSLEQCQGTCAASEN
LPTCEQPVESGPCAGNFERWYYDNETDICRPFTYGGCKGNKNNYPTEHACNYNCRQPG
VLKAEPNKQDNEIGQNPCDTFDAECQELRCPYGVRRVAARSQPECTQCICENPCEGYS
CPEGQQCAIDVASSDDRQFAPVCRDIYKPGECPALSANASGCARECYTDADCRGDNKC
CSDGCGQLCVHPARPTQPPRTQAPVVSYPGDARAALEPKEAHELDVQTAIGGIAVLRC
FATGNPAPNITWSLKNLVINTNKGRYVLTANGDLTIVQVRQTDDGTYVCVASNGLGEP
VRREVALQVTVNVHAVLALEPKNSYTPGSTIVMSCSVQGYPEPNVTWIKDDVPLYNNE
RVQITYQPHRLVLSDVTSADSGKYTCRASNAYTYANGEANVSIQSVVPVSPECVDNPY
FANCKLIVKGRYCSNPYYTQFCCRSCTLAGQVASPPLHPNAV"
ORIGIN
1 atcagttgct ggcgtgccgt caaaccctgc ggatgtgtgc cgaatcgagg cggatacttc
61 gacttcgact tcgactccga ctttgactct taggatagtg cgcgatcgtt cgacctaata
121 tatcctgcgg caatgagcag gcgcaaagtg ccgagtggat tctgatttca agtgacaact
181 ctgtgccaga taattaaaac tcaagtggtg ctccactcaa gtgctagcca ctctgcgggg
241 acaaggaacg acacagaacg atacaaaata aatagatata tatatatata tatatatata
301 tatatatata tattcgagtg ggtgagaaac gcgaaaagtg aggcgacgct tattgtgctg
361 tcctgccagc aaggagccac aaaatggatt tatcgaggcg gttgtgctca actgccttgg
421 tagcattcat tgttctggcc agcattcatg attcccagag cagattccct ggactcagac
481 aaaaaagaca atatggggcg aacatgtact tgccggagag ctcggtgacg cccggcggcg
541 agggtaacga tcccgatgag tggacacctt ggagctcacc ctcggactgt tccaggacct
601 gcggcggtgg agtgtcctac cagactcggg agtgcctgcg aagagatgat cgtggcgagg
661 cagtctgcag tggaggcagt cgccgttact tctcctgcaa cacccaagac tgtccggagg
721 aagaatccga cttccgggcg cagcagtgct cccgcttcga caggcagcag tttgatggag
781 tcttctacga gtgggtgccg tacacgaatg cacccaatcc ctgcgagctg aactgtatgc
841 ccaagggcga gcggttctac taccgtcagc gggagaaggt ggtggacgga acccgctgca
901 acgacaagga cctcgacgtg tgcgtaaacg gggagtgcat gccggtgggc tgcgacatga
961 tgctgggtag cgatgccaag gaggacaagt gccgaaagtg tggtggtgat ggcagcacct
1021 gcaagaccat tcgcaacacc atcaccacga aggatctggc tcctggatac aatgacttgc
1081 tgctccttcc agagggagcc actaacattc gtatcgagga gactgtgccc tccagcaatt
1141 acctggcctg ccggaaccac agtggacact actacctgaa cggcgattgg cgcatcgact
1201 tcccacgccc catgttcttc gcgaactcgt ggtggaacta ccaacgaaag ccaatgggct
1261 tcgccgctcc cgaccaactg acctgcagcg gtcccatctc ggagagcctc ttcatagtta
1321 tgttggtgca ggagaagaac atcagcctcg actacgagta cagcattccg gagagcctta
1381 gtcactcgca gcaggatacg cacacatgga cgcatcacca gttcaatgcc tgcagtgctt
1441 cctgcggcgg tggctctcag agtcgaaagg tcacatgcaa caatcgcatc accttggcgg
1501 aagtcaatcc atcgctgtgc gaccaaaagt ccaagccagt ggaggaacag gcttgcggca
1561 cggaaccgtg tgcaccacac tgggttgagg gagagtggtc caagtgctct aagggctgcg
1621 ggtccgatgg cttccaaaac aggagcatca cctgcgagcg aatctcctct tcgggcgagc
1681 atacagttga agaagatgcc gtttgcctaa aggaggtggg caacaagccg gccaccaaac
1741 aggagtgcaa ccgcgatgta aagaactgcc ccaagtatca tttaggacct tggacgccgt
1801 gtgataagct ttgcggcgac ggaaagcaga cacgaaaggt gacctgcttc atcgaggaga
1861 acggacacaa acgagtcctg cccgaagaag attgcgtgga ggagaagcca gagacggaga
1921 agtcctgcct cttaacgcct tgtgagggcg ttgactggat aatctcccaa tggagcggct
1981 gcaatgcgtg tggtcagaat accgaaacac gtaccgccat ctgtggcaac aaggaaggta
2041 aggtgtatcc ggaggaattc tgtgaaccag aggtacccac tctatcccgg ccgtgcaaat
2101 cccccaagtg cgaggcgcaa tggttctcct cggagtggag caagtgctct gctccttgcg
2161 gaaaaggtgt caaatctcgc attgtcattt gcggggagtt cgatggcaag acggtaactc
2221 cagcagatga tgactctaag tgcaacaaag aaacgaaacc ggaatcagaa caggattgtg
2281 agggcgagga gaaggtttgc cccggcgaat ggttcactgg accttggggc aagtgcagca
2341 agccttgtgg tgggggtgag cgagtccgtg aggtcctgtg tctttccaat ggaaccaagt
2401 cagtcaactg cgatgaagaa aaggtcgaac ctctatctga aaagtgtaac tctgaagcct
2461 gcactgagga tgagatttta cctttgacca gtactgataa gcccatcgag gatgacgagg
2521 aggattgcga tgaagatggt attgagttga tcagcgatgg gttgtcagac gatgaaaaga
2581 gcgaagatgt gatcgacttg gagggaactg caaagacgga aactacgccc gaggccgaag
2641 atcttatgca aagtgacagc ccgacaccct atgatgagtt tgaatcgact ggtaccacat
2701 ttgagggatc gggatatgat tcagaatcaa ccaccgacag cggcatttcc acagaaggaa
2761 gcggtgatga cgaagaaacg tctgaggctt ccactgattt gtctagctcc acggattccg
2821 gttccacctc cagtgactct acttccagcg actcaagctc cagtatttcc agcgatgcaa
2881 cttctgaagc accggcatcc tcagtttctg attcaagcga ttccacagat gcatccacag
2941 aaaccacagg agtttctgat gactccactg atgtctcgag ctcaacagaa gcctccgcct
3001 cggagtcgac cgatgtctca ggcgcatcag attccacggg ctccaccaat gcttccgact
3061 caactcctga aagctccacg gaagcctcaa gttccacaga tgactccacg gactcttcgg
3121 acaattcttc gaacgttagt gagtcatcaa cagaggcttc ttcctcatcc gtatctgatt
3181 ctaatgacag ttctgatgga tccaccgatg gcgtatccag cacaactgag aattcatcag
3241 acagtacttc tgatgccact tccgactcaa cagcatcttc agattctacg gactctactt
3301 ccgatcagac aactgaaact acccctgaat catcgactga ttcaacagaa tcgtctaccc
3361 tggacgcatc ctcaacaaca gatgcctcat cgactagcga gtcttcatcg gaaagctcaa
3421 cagatggatc ttcaactaca tccaactcgg catcaagcga aaccaccggg ctgtccagtg
3481 atggatcaac cacagatgca actacagctg cttctgacaa cactgacatc accactgatg
3541 gctcaactga tgaatccact gatggttcct ctaatgcctc tactgagggc tctactgaag
3601 gcgcaagcga ggacaccaca atctccacgg agtcctccgg atcaaccgaa agcaccgacg
3661 ccatcgccag tgatggttcg accaccgagg gaagtaccgt cgaggacctg tccagttcca
3721 caagctctga tgttacatct gattctacca tcaccgactc ctcaccttcc actgaagtat
3781 ctggttccac agactcatcc tcttccacag atggttcctc aacagatgct tcctccactg
3841 aggcttcctc taccgatgtc actgaatcta cagatagtac tgttagtgga ggtaccagcg
3901 acactacgga aagcggtcca acggaggaaa gtactaccga aggctccact gaaagcacaa
3961 ccgaaggatc cacagacagc acccaatcca ccgatctgga cagcaccacc agtgatatct
4021 ggagcaccag tgataaggat gacgaatcgg agagcagtac tccttactcc tttgattctg
4081 aagttaccaa gagcaagccc cgtaaatgta agcctaagaa gagtacctgc gccaaatccg
4141 agtacggttg ctgtccggat ggtaagtcca ctccgaaggg accgtttgac gagggctgtc
4201 ccattgcaaa gacctgtgcg gatacaaagt acggttgttg cttggacgga gtgtctccgg
4261 ctaagggcaa gaataacaag ggttgtccca agtcccagtg cgctgagact ctctttggct
4321 gctgtcccga taaattcacc gccgccgatg gtgagaatga tgagggatgt ccagagacca
4381 ctactgtacc acctacgact accacagagg agacacagcc agagactact actgagatcg
4441 aaggatcagg tcaagactcg acgacttctg agccagacac caagaagtcc tgctccttct
4501 ccgaatttgg ttgctgtccc gatgcggaaa catccgccaa gggccctgac ttcgagggat
4561 gtggtcttgc gtcaccggtt gccaagggct gcgcagagtc tgagaacggt tgctgtccgg
4621 atggacaaac acctgcaagc ggtccgaatg gcgaaggttg ctctggatgc acacgtgagc
4681 gctttggatg ttgtccggac tcccaaaccc cggcccatgg tcccaacaag gagggctgct
4741 gcttggacac tcagtttggc tgctgccccg acaacatctt ggccgcgcgt ggacccaaca
4801 acgagggctg cgaatgccac tacactccgt atggctgctg cccggacaat aagtcggccg
4861 caactggcta caaccaggag ggatgcgcct gcgagacgac ccagtatggc tgctgtcccg
4921 acaagatcac tgccgccaag ggacccaagc acgagggctg cccttgcgag accacccagt
4981 tcggatgctg tccagatggg ctcaccttcg ccaagggacc gcaccaccac ggatgccact
5041 gcactcagac ggagttcaag tgctgcgacg acgagaagac cccggccaag ggccccaacg
5101 gcgatggctg cacgtgtgtg gagagcaagt tcggttgctg tcccgatgga gtcaccaagg
5161 cgacggacga gaagttcggt ggatgcgaga atgtccagga gccaccgcaa aaggcctgcg
5221 gcctgcccaa ggagacgggc acctgcaata actacagcgt caagtactac ttcgacacct
5281 cctacggagg atgcgctcgc ttttggtacg gtggctgcga tggcaacgac aaccgctttg
5341 agagcgaggc cgagtgcaag gacacctgcc aggattacac cggcaagcac gtatgcctgc
5401 tgcccaagag cgcaggtccc tgcactggct tcaccaagaa atggtacttc gatgtcgacc
5461 gcaaccggtg cgaggagttc cagtacggcg gatgctacgg taccaataat cgcttcgata
5521 gcttggaaca gtgccagggc acttgtgctg ccagtgaaaa tctgcctacc tgtgaacaac
5581 ctgtggagag cggaccatgt gccggaaact tcgagcgttg gtactacgac aacgagacgg
5641 acatctgccg acccttcacc tatggtggat gcaagggcaa caagaacaac tatcccacgg
5701 aacatgcctg caactacaac tgccgccagc ccggcgtgct taaagcggaa cccaacaagc
5761 aggacaacga aattggacaa aatccgtgcg ataccttcga tgcggagtgc caggagctcc
5821 gctgtccata cggcgttcgc cgtgtggccg ccaggtccca gccagagtgc acgcagtgca
5881 tctgcgagaa tccgtgcgag ggctacagtt gcccggaggg ccaacagtgc gccatcgatg
5941 tggccagttc cgacgatcgc cagtttgctc cagtgtgtcg cgatatttat aagccaggag
6001 agtgcccggc tctttcagcg aatgccagtg gatgtgcccg ggaatgctac accgatgccg
6061 actgtcgtgg agacaacaag tgctgcagcg acggctgcgg acagctgtgt gtgcatcctg
6121 ctcgtccaac tcagccgccc aggactcagg ctccagtggt ctcctatccg ggcgatgcca
6181 gagccgctct ggaacccaag gaggcgcatg agcttgatgt ccagacagcc atcggcggca
6241 tagccgtgct gcgctgcttc gccaccggca atccagcccc gaatatcacc tggtcgctca
6301 agaacttggt gatcaacacg aacaagggac gatatgtgct gaccgccaac ggtgatctga
6361 ccattgtcca ggtgcgccaa acagacgatg gcacctacgt ctgcgtggcc agcaatggtc
6421 tgggagaacc cgtgcgtcgt gaggtcgccc tccaggttac agttaatgtt catgccgtgt
6481 tggctctgga gccgaagaac agctacaccc caggctccac cattgtcatg agctgctccg
6541 tgcagggcta tccagaaccg aatgtcacat ggatcaagga cgacgtgcct ctgtacaaca
6601 acgagcgtgt tcaaattaca taccaaccac atcgcctggt gctgagtgat gtcacatccg
6661 cggattccgg aaagtacact tgccgggcca gcaatgcgta cacctacgcc aatggagagg
6721 ccaatgtgtc cattcaatct gttgtaccag tgtcgcccga gtgcgttgac aatccgtact
6781 tcgctaactg caagcttatc gtcaagggca gatactgttc caatccgtac tacacccagt
6841 tctgctgccg atcctgcacg ttggcgggcc aggtggcctc gcctcctctg catcccaatg
6901 cggtgtaatt ccacggagcg agatagagca gagtaatttt gtttagtttt cggattgaat
6961 tgagtttaaa cgcaccacac aagaataatt ggatcgacat tcgcggacat cccatcatcc
7021 aaaagcagag agaccaaaaa gccaatcgtt gcttagccat agccaccata tatataccta
7081 catatatata gcctaccgat caagaacgaa cgaacttcta ttgtagtatt ttactctctt
7141 ccaggacaaa agcaaatagt attagtgatt ttatgtttgt gttcctattt attcttgata
7201 acgagtaacc ttaaattcaa tcgaggaaag aaaagcggct aaaacgaatt tgccttctac
7261 tttttagttt ctacgacatt tctgtgcaac gagtaaagca tttaagccta aaaaccaata
7321 attgtaaata aattaaaact acataataaa gagtgcatat gtataaaaga tt
//