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Saccharomyces cerevisiae S288C porin POR1 (POR1), partial mRNA

NCBI Reference Sequence: NM_001182894.1

FASTA Graphics 

LOCUS       NM_001182894             852 bp    mRNA    linear   PLN 17-DEC-2024
DEFINITION  Saccharomyces cerevisiae S288C porin POR1 (POR1), partial mRNA.
ACCESSION   NM_001182894
VERSION     NM_001182894.1
DBLINK      BioProject: PRJNA128
KEYWORDS    RefSeq.
SOURCE      Saccharomyces cerevisiae S288C
  ORGANISM  Saccharomyces cerevisiae S288C
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (bases 1 to 852)
  AUTHORS   Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
            Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
            Weng,S. and Cherry,J.M.
  TITLE     New data and collaborations at the Saccharomyces Genome Database:
            updated reference genome, alleles, and the Alliance of Genome
            Resources
  JOURNAL   Genetics 220 (4) (2022)
   PUBMED   34897464
REFERENCE   2  (bases 1 to 852)
  AUTHORS   Philippsen,P., Kleine,K., Pohlmann,R., Dusterhoft,A., Hamberg,K.,
            Hegemann,J.H., Obermaier,B., Urrestarazu,L.A., Aert,R.,
            Albermann,K., Altmann,R., Andre,B., Baladron,V., Ballesta,J.P.,
            Becam,A.M., Beinhauer,J., Boskovic,J., Buitrago,M.J., Bussereau,F.,
            Coster,F., Crouzet,M., D'Angelo,M., Dal Pero,F., De Antoni,A.,
            Hani,J. et al.
  TITLE     The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV
            and its evolutionary implications
  JOURNAL   Nature 387 (6632 SUPPL), 93-98 (1997)
   PUBMED   9169873
REFERENCE   3  (bases 1 to 852)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   4  (bases 1 to 852)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2024) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (bases 1 to 852)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2012) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   6  (bases 1 to 852)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2011) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   7  (bases 1 to 852)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (26-MAY-2010) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   8  (bases 1 to 852)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by SGD. This record
            is derived from an annotated genomic sequence (NC_001146).
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: SGD
            Annotation Status   :: Full Annotation
            Annotation Version  :: R64-4-1
            URL                 :: http://www.yeastgenome.org/
            ##Genome-Annotation-Data-END##
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..852
                     /organism="Saccharomyces cerevisiae S288C"
                     /mol_type="mRNA"
                     /strain="S288C"
                     /db_xref="taxon:559292"
                     /chromosome="XIV"
     gene            <1..>852
                     /gene="POR1"
                     /locus_tag="YNL055C"
                     /gene_synonym="OMP2"
                     /db_xref="GeneID:855669"
     CDS             1..852
                     /gene="POR1"
                     /locus_tag="YNL055C"
                     /gene_synonym="OMP2"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:22842922]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:16823961|PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0005741
                     mitochondrial outer membrane
                     [PMID:7499333|PMID:16689936|PMID:16407407]"
                     /experiment="EXISTENCE:direct assay:GO:0006811 monoatomic
                     ion transport [PMID:9593723]"
                     /experiment="EXISTENCE:direct assay:GO:0008308
                     voltage-gated monoatomic anion channel activity
                     [PMID:9593723]"
                     /experiment="EXISTENCE:direct assay:GO:0017128
                     phospholipid scramblase activity [PMID:38065946]"
                     /experiment="EXISTENCE:direct assay:GO:0048039 ubiquinone
                     binding [PMID:38906315|PMID:28051849]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0005741
                     mitochondrial outer membrane [PMID:38065946]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006915
                     apoptotic process [PMID:17822411]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0007005
                     mitochondrion organization [PMID:11488609]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0042307
                     positive regulation of protein import into nucleus
                     [PMID:29359182]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0045332
                     phospholipid translocation [PMID:38065946]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0045454 cell
                     redox homeostasis [PMID:18768136]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0051027 DNA
                     transport [PMID:19056337]"
                     /experiment="EXISTENCE:physical interaction:GO:0005739
                     mitochondrion [PMID:16962558]"
                     /experiment="EXISTENCE:physical interaction:GO:0044289
                     mitochondrial inner-outer membrane contact site
                     [PMID:37073556]"
                     /note="Mitochondrial porin and phospholipid scramblase;
                     voltage-dependent anion channel in the outer mitochondrial
                     membrane required for maintenance of mitochondrial osmotic
                     stability and membrane permeability; scramblase involved
                     in mitochondrial transbilayer translocation of
                     phospholipids; ubiquinone binding protein; couples
                     glutathione pools of the intermembrane space and the
                     cytosol; phosphorylated; protein abundance increases in
                     response to DNA replication stress; orthologous to human
                     VDAC1 and 2"
                     /codon_start=1
                     /product="porin POR1"
                     /protein_id="NP_014343.1"
                     /db_xref="GeneID:855669"
                     /db_xref="SGD:S000005000"
                     /translation="MSPPVYSDISRNINDLLNKDFYHATPAAFDVQTTTANGIKFSLK
                     AKQPVKDGPLSTNVEAKLNDKQTGLGLTQGWSNTNNLQTKLEFANLTPGLKNELITSL
                     TPGVAKSAVLNTTFTQPFFTARGAFDLCLKSPTFVGDLTMAHEGIVGGAEFGYDISAG
                     SISRYAMALSYFAKDYSLGATLNNEQITTVDFFQNVNAFLQVGAKATMNCKLPNSNVN
                     IEFATRYLPDASSQVKAKVSDSGIVTLAYKQLLRPGVTLGVGSSFDALKLSEPVHKLG
                     WSLSFDA"
ORIGIN      
        1 atgtctcctc cagtttacag cgatatctcc agaaatatca atgacctatt gaacaaggat
       61 ttctatcatg ctaccccagc tgcctttgat gtgcaaacaa caaccgccaa tggcattaag
      121 ttctcattga aggctaaaca gcctgtcaaa gacggtccac tgtctactaa cgtggaagca
      181 aagttgaatg acaagcaaac cggcttgggt ctaactcaag gctggtctaa cacaaacaac
      241 ttgcaaacca aattagagtt tgccaacttg acccctggtc taaagaacga attgatcact
      301 tctttgactc caggcgtcgc caagtccgcc gtcttaaaca ctacgttcac acaacctttc
      361 ttcaccgcaa gaggtgcctt tgacttgtgt ttgaagtcac caacatttgt tggtgactta
      421 actatggccc acgaaggtat tgttggtggc gcagagtttg gttacgatat cagcgccggt
      481 tccatttctc gttatgccat ggctttaagt tatttcgcca aagactactc cttgggcgct
      541 acattgaaca acgagcaaat aactaccgtt gacttcttcc aaaacgtcaa cgccttttta
      601 caggtcggtg ctaaggctac aatgaactgc aaactaccta actccaatgt caacatcgaa
      661 ttcgccacta gatatttgcc tgatgcatct tcccaagtta aggctaaggt gtccgattcc
      721 ggtattgtca ctttggctta caagcaattg ttaagacctg gcgtcactct gggtgtcggt
      781 tcctctttcg atgctttgaa gttgtctgaa cctgttcaca agctaggttg gtctttgtcc
      841 ttcgacgctt ga
//
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