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Saccharomyces cerevisiae S288C histone H1 (HHO1), partial mRNA

NCBI Reference Sequence: NM_001183941.1

FASTA Graphics 

LOCUS       NM_001183941             777 bp    mRNA    linear   PLN 17-DEC-2024
DEFINITION  Saccharomyces cerevisiae S288C histone H1 (HHO1), partial mRNA.
ACCESSION   NM_001183941
VERSION     NM_001183941.1
DBLINK      BioProject: PRJNA128
KEYWORDS    RefSeq.
SOURCE      Saccharomyces cerevisiae S288C
  ORGANISM  Saccharomyces cerevisiae S288C
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (bases 1 to 777)
  AUTHORS   Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
            Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
            Weng,S. and Cherry,J.M.
  TITLE     New data and collaborations at the Saccharomyces Genome Database:
            updated reference genome, alleles, and the Alliance of Genome
            Resources
  JOURNAL   Genetics 220 (4) (2022)
   PUBMED   34897464
REFERENCE   2  (bases 1 to 777)
  AUTHORS   Bussey,H., Storms,R.K., Ahmed,A., Albermann,K., Allen,E.,
            Ansorge,W., Araujo,R., Aparicio,A., Barrell,B., Badcock,K.,
            Benes,V., Botstein,D., Bowman,S., Bruckner,M., Carpenter,J.,
            Cherry,J.M., Chung,E., Churcher,C., Coster,F., Davis,K.,
            Davis,R.W., Dietrich,F.S., Delius,H., DiPaolo,T., Hani,J. et al.
  TITLE     The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI
  JOURNAL   Nature 387 (6632 SUPPL), 103-105 (1997)
   PUBMED   9169875
REFERENCE   3  (bases 1 to 777)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   4  (bases 1 to 777)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2024) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (bases 1 to 777)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2015) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   6  (bases 1 to 777)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2011) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   7  (bases 1 to 777)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by SGD. This record
            is derived from an annotated genomic sequence (NC_001148).
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: SGD
            Annotation Status   :: Full Annotation
            Annotation Version  :: R64-4-1
            URL                 :: http://www.yeastgenome.org/
            ##Genome-Annotation-Data-END##
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..777
                     /organism="Saccharomyces cerevisiae S288C"
                     /mol_type="mRNA"
                     /strain="S288C"
                     /db_xref="taxon:559292"
                     /chromosome="XVI"
     gene            <1..>777
                     /gene="HHO1"
                     /locus_tag="YPL127C"
                     /db_xref="GeneID:855976"
     CDS             1..777
                     /gene="HHO1"
                     /locus_tag="YPL127C"
                     /experiment="EXISTENCE:direct assay:GO:0000785 chromatin
                     [PMID:22586276]"
                     /experiment="EXISTENCE:direct assay:GO:0003677 DNA binding
                     [PMID:11574687]"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:11914276|PMID:9046096]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006355
                     regulation of DNA-templated transcription [PMID:11574687]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0030261
                     chromosome condensation [PMID:22586276]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0043934
                     sporulation [PMID:22586276]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0045910
                     negative regulation of DNA recombination [PMID:12820979]"
                     /experiment="EXISTENCE:mutant phenotype:GO:2000779
                     regulation of double-strand break repair [PMID:31821952]"
                     /note="Histone H1, linker histone with roles in meiosis
                     and sporulation; decreasing levels early in sporulation
                     may promote meiosis, and increasing levels during
                     sporulation facilitate compaction of spore chromatin;
                     binds to promoters and within genes in mature spores; may
                     be recruited by Ume6p to promoter regions, contributing to
                     transcriptional repression outside of meiosis; suppresses
                     DNA repair involving homologous recombination"
                     /codon_start=1
                     /product="histone H1"
                     /protein_id="NP_015198.1"
                     /db_xref="GeneID:855976"
                     /db_xref="SGD:S000006048"
                     /translation="MAPKKSTTKTTSKGKKPATSKGKEKSTSKAAIKKTTAKKEEASS
                     KSYRELIIEGLTALKERKGSSRPALKKFIKENYPIVGSASNFDLYFNNAIKKGVEAGD
                     FEQPKGPAGAVKLAKKKSPEVKKEKEVSPKPKQAATSVSATASKAKAASTKLAPKKVV
                     KKKSPTVTAKKASSPSSLTYKEMILKSMPQLNDGKGSSRIVLKKYVKDTFSSKLKTSS
                     NFDYLFNSAIKKCVENGELVQPKGPSGIIKLNKKKVKLST"
ORIGIN      
        1 atggcaccca agaaatccac taccaagacc acaagtaagg gcaagaagcc tgcaaccagc
       61 aaaggcaagg agaaatcaac ttccaaggcc gctatcaaga aaaccacggc aaaaaaggag
      121 gaagcttcct ccaagagtta cagggagttg atcattgaag ggctcacggc tttgaaggaa
      181 cgtaagggat ccagtcgtcc ggcactcaag aagtttatca aggaaaacta cccgatcgtc
      241 ggatccgcaa gcaactttga tttgtacttc aacaatgcca taaagaaggg tgtggaggcc
      301 ggcgattttg aacagccaaa gggacccgct ggtgctgtga aactggccaa gaagaaatct
      361 ccagaagtaa agaaagaaaa agaggtcagt ccaaaaccca agcaagccgc cacttctgtg
      421 agtgcaaccg catcaaaagc gaaagccgca tccacgaagc tagcgccaaa gaaagtagtg
      481 aaaaaaaaat cgcctactgt taccgccaag aaggcctctt cgccttcttc attgacctac
      541 aaggaaatga tccttaaaag catgcctcaa cttaatgacg gtaagggctc cagccgtatc
      601 gttttaaaga agtatgtcaa ggacactttc tcctccaagt tgaaaacaag ctcaaatttt
      661 gactatctgt tcaatagcgc tatcaagaaa tgtgttgaaa acggcgagtt agtgcaacca
      721 aagggcccct ccggcattat taaactaaac aagaagaagg tcaaactctc cacgtaa
//
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