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Mus musculus exocyst complex component 3-like (Exoc3l), transcript variant 3, mRNA

NCBI Reference Sequence: NM_001428421.1

FASTA Graphics 

LOCUS       NM_001428421            2538 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus exocyst complex component 3-like (Exoc3l), transcript
            variant 3, mRNA.
ACCESSION   NM_001428421 XM_006531070
VERSION     NM_001428421.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2538)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2538)
  AUTHORS   Takashima,S., Okamura,E., Ichiyama,Y., Nishi,K., Shimizu,A.,
            Watanabe,C., Muto,M., Matsumoto,S., Tsukiyama-Fujii,S.,
            Tsukiyama,T., Ogita,H., Nishi,E., Ohji,M., Sugiyama,F.,
            Takahashi,S., Mizuno,S., Mizutani,K.I. and Ema,M.
  TITLE     Null mutation of exocyst complex component 3-like does not affect
            vascular development in mice
  JOURNAL   Exp Anim 73 (1), 93-100 (2024)
   PUBMED   37661429
  REMARK    GeneRIF: Null mutation of exocyst complex component 3-like does not
            affect vascular development in mice.
REFERENCE   3  (bases 1 to 2538)
  AUTHORS   Saito,T., Shibasaki,T. and Seino,S.
  TITLE     Involvement of Exoc3l, a protein structurally related to the
            exocyst subunit Sec6, in insulin secretion
  JOURNAL   Biomed Res 29 (2), 85-91 (2008)
   PUBMED   18480549
REFERENCE   4  (bases 1 to 2538)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124584.5.
            
            On Mar 12, 2024 this sequence version replaced XM_006531070.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13422589.508635.1,
                                           SRR13422600.866833.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-193               AC124584.5         97381-97573
            194-314             AC124584.5         97733-97853
            315-490             AC124584.5         98044-98219
            491-710             AC124584.5         98295-98514
            711-1320            AC124584.5         99618-100227
            1321-1438           AC124584.5         100300-100417
            1439-1564           AC124584.5         100502-100627
            1565-1665           AC124584.5         100730-100830
            1666-1776           AC124584.5         101034-101144
            1777-1906           AC124584.5         102427-102556
            1907-2029           AC124584.5         102675-102797
            2030-2185           AC124584.5         102875-103030
            2186-2310           AC124584.5         103123-103247
            2311-2538           AC124584.5         103329-103556
FEATURES             Location/Qualifiers
     source          1..2538
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 53.04 cM"
     gene            1..2538
                     /gene="Exoc3l"
                     /gene_synonym="C730015A04Rik; Exoc3l1"
                     /note="exocyst complex component 3-like"
                     /db_xref="GeneID:277978"
                     /db_xref="MGI:MGI:3041195"
     exon            1..193
                     /gene="Exoc3l"
                     /gene_synonym="C730015A04Rik; Exoc3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            194..314
                     /gene="Exoc3l"
                     /gene_synonym="C730015A04Rik; Exoc3l1"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    221..223
                     /gene="Exoc3l"
                     /gene_synonym="C730015A04Rik; Exoc3l1"
                     /note="upstream in-frame stop codon"
     CDS             281..2500
                     /gene="Exoc3l"
                     /gene_synonym="C730015A04Rik; Exoc3l1"
                     /note="isoform 1 is encoded by transcript variant 3;
                     exocyst complex component 3-like protein"
                     /codon_start=1
                     /product="exocyst complex component 3-like protein isoform
                     1"
                     /protein_id="NP_001415350.1"
                     /db_xref="GeneID:277978"
                     /db_xref="MGI:MGI:3041195"
                     /translation="MDSKIQPTLRPGSSCPRPEWPEQERAEQLARGAALKWASGIFYR
                     PEQLTRLGQYRSREIQRNYSLEARIKSVVQSYLEGVQTGVWQLTRALEAVQGTREALS
                     QAHHLLKGLSRTSQTLEPLRECVVQHKQLQILTRLLPRLQAVPATVAHTQTLIDSERL
                     LEAYVSLRELEQLKEETLAPLGGLELPIFQGLGLLAEALGQAVEAAAGAAGRLAREDP
                     ALLVAAIRVAEVETERTILGQAPRDWRQRCLRALQEGLERVHFASPVLPEPGALAGWL
                     EALQVALPAELATAEALVAPCCPPSYRVVELWAHTLHSGLRRSVQQLLAGPELGAADT
                     FALLHWALHVYTGKEMMGNLELGPEADVSQLEPLLTSENIEQLEAAFVAQVQVSVAQW
                     LKKALDGEVAEWSGEQEPPTDPSGFYHSPMPAIVLQILAENIQVTNLISDSLHRRAHN
                     MAVSELGAFLRSFSDALIRFSRDHLRGDAVAPHYVPYLLSAFNHQSALRSSVSVLLPD
                     GEASGVLAPVEAALDDVQRRICRLVLEVLQVELQPLFSALPSRRWLLSSELLDGVCEQ
                     TSHFCQDFWRVRKPGVQLLLAEAERTVVLQYLRALMQGRLVCRGTDERSQAAERLRQD
                     AAQLKELFLGLGLEESAHCAPVLLALRELLNLHDPTLLGLEVAGLRQQFPDVSEDHVS
                     ALLDLRGDVSREHRQAALSSLQAGPPPSPSTGRRALFSLVPTPTPSLSSCLPSGPCS"
     misc_feature    281..1390
                     /gene="Exoc3l"
                     /gene_synonym="C730015A04Rik; Exoc3l1"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BI71.1);
                     Region: Mediates interaction with EXOC2, EXOC4 and EXOC5.
                     /evidence=ECO:0000269|PubMed:18480549"
     misc_feature    281..343
                     /gene="Exoc3l"
                     /gene_synonym="C730015A04Rik; Exoc3l1"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BI71.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    2372..2434
                     /gene="Exoc3l"
                     /gene_synonym="C730015A04Rik; Exoc3l1"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BI71.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     exon            315..490
                     /gene="Exoc3l"
                     /gene_synonym="C730015A04Rik; Exoc3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            491..710
                     /gene="Exoc3l"
                     /gene_synonym="C730015A04Rik; Exoc3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            711..1320
                     /gene="Exoc3l"
                     /gene_synonym="C730015A04Rik; Exoc3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1321..1438
                     /gene="Exoc3l"
                     /gene_synonym="C730015A04Rik; Exoc3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1439..1564
                     /gene="Exoc3l"
                     /gene_synonym="C730015A04Rik; Exoc3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1565..1665
                     /gene="Exoc3l"
                     /gene_synonym="C730015A04Rik; Exoc3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1666..1776
                     /gene="Exoc3l"
                     /gene_synonym="C730015A04Rik; Exoc3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1777..1906
                     /gene="Exoc3l"
                     /gene_synonym="C730015A04Rik; Exoc3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1907..2029
                     /gene="Exoc3l"
                     /gene_synonym="C730015A04Rik; Exoc3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            2030..2185
                     /gene="Exoc3l"
                     /gene_synonym="C730015A04Rik; Exoc3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            2186..2310
                     /gene="Exoc3l"
                     /gene_synonym="C730015A04Rik; Exoc3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            2311..2538
                     /gene="Exoc3l"
                     /gene_synonym="C730015A04Rik; Exoc3l1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2518..2523
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Exoc3l"
                     /gene_synonym="C730015A04Rik; Exoc3l1"
                     /note="hexamer: AATAAA"
     polyA_site      2538
                     /gene="Exoc3l"
                     /gene_synonym="C730015A04Rik; Exoc3l1"
                     /note="major polyA site"
ORIGIN      
        1 aggggtttct gggccgtgaa gtgggagaga ggcttccttg gggagaggaa tttggctgct
       61 ggtgccaaag gagctggagt ccctccggtc ccgtgagcag tgagggtgtg cccagctctg
      121 caggagcgag aaggctactc tcaaggccaa ggccacttgc agaggaggga gaactggaca
      181 ccggtcagat ctgcggagcc caaggaacat ccgctctgcc tgatctcctc caggcactcg
      241 ctcccactcc taccacatcg gcagcagctc taggcaaact atggacagca agatacagcc
      301 cacacttcgt cctggatctt cctgcccaag gcctgagtgg ccagagcagg agagggccga
      361 acagctggct cggggtgcag cactcaagtg ggcttcaggc atcttctacc ggccagagca
      421 gctgaccagg ctgggccagt accgaagccg tgaaatacag cgtaactatt ccctggaagc
      481 aagaattaag tcagtggtgc agtcctacct ggaaggtgtg cagactggtg tgtggcagct
      541 gacccgagcc ctcgaggctg tgcagggaac tcgtgaagct ttgagccagg cccatcactt
      601 actaaagggt ttgtctcgga cctcacaaac cctggaaccc ctgagggaat gtgttgtcca
      661 gcacaaacaa cttcagatcc tgactcggtt gttgccaagg ctacaagcag tgccggctac
      721 agtggcccac acgcagaccc tgatagactc tgagcgactc ttggaggcat atgtgagcct
      781 gcgggaacta gagcagctga aagaggagac actggcaccc ctaggaggtc tggagttgcc
      841 aatcttccag gggctaggcc ttctggctga ggccctaggc caagctgtgg aggcggctgc
      901 aggagctgcg gggcggctgg cacgagagga cccagccctg ctggtagctg ctattcgtgt
      961 ggcagaggtg gagactgagc gcacaatcct ggggcaggca ccccgagact ggcggcagcg
     1021 atgtcttcgg gcgctacagg agggcctgga gcgggtccac tttgcatcgc ctgtgcttcc
     1081 ggagccaggg gctctggcgg ggtggcttga ggctctgcag gtagccttgc ccgccgagtt
     1141 ggcaacagcg gaggcattgg tggcaccctg ctgcccacca agctaccgtg tggttgagct
     1201 atgggcccac accctgcaca gtggcctgcg ccgtagcgtg cagcaactcc tcgcggggcc
     1261 cgagctagga gctgctgaca cgtttgcctt gctgcactgg gcactgcatg tgtacacggg
     1321 gaaggaaatg atggggaact tggaactggg gcctgaggct gatgtgtccc agctagagcc
     1381 cctcttgacc tcagagaaca ttgagcagct ggaggcagcc tttgtggctc aggttcaggt
     1441 aagtgtggct cagtggctga agaaggcact ggatggagag gtagcagagt ggagcgggga
     1501 acaggagccc cccacagatc catccggttt ctaccactcc ccaatgccag ccattgtcct
     1561 gcagatcctg gctgaaaaca ttcaagtgac caacctgatt agtgactcat tgcatcggcg
     1621 ggcgcataac atggcagtgt cagagctggg cgcattcttg agaagcttca gcgacgctct
     1681 gatccgattc tctcgagacc atctcagggg agacgccgtg gcccctcact atgtgcccta
     1741 cctactgtct gccttcaacc accaatcagc actgagatct tcggtctcgg tcctgctgcc
     1801 ggacggggaa gcttccgggg tcttagctcc agtggaagct gcgctggacg acgtacaaag
     1861 gaggatctgc cgcctggttt tggaagtact gcaggttgag ctccagcccc tgttctccgc
     1921 tctgccctcg cgccggtggc tattgagttc tgagttgcta gatggtgtgt gtgagcagac
     1981 gtcgcacttc tgccaggact tctggcgcgt acggaagcct ggtgttcagc tgctgctggc
     2041 agaggcggaa cgaaccgtgg tgttacaata cctaagggct ctgatgcagg gccgcctagt
     2101 gtgccgcggt acggacgagc ggagccaggc ggctgagcga cttcggcagg atgctgccca
     2161 gctcaaagag cttttccttg gtttgggcct ggaagagagc gctcactgcg cgcccgtcct
     2221 gctcgcgctg agggaactgc tcaacctcca cgaccccaca ctgcttggcc tcgaggtggc
     2281 aggcttgagg cagcaatttc ccgacgtgag cgaggatcac gtctctgccc tcttggacct
     2341 gcgcggagac gtgtcccgag agcatcgtca ggcagcactc agttcgctgc aggcgggtcc
     2401 accgccctca ccgtccactg gccgccgggc gctcttcagc ctggtaccga cgcctacgcc
     2461 ctccctgtcc tcctgcctcc cttcaggtcc ctgctcctga cacccatctg tttgcgtaat
     2521 aaagccacgt ctacgaca
//
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