Homo sapiens pellino E3 ubiquitin protein ligase family member 2 (PELI - Nucleotide

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PELI2 is a negative regulator of STING signaling that is dynamically repressed during viral infection. [Mol Cell. 2024]
PELI2 is a negative regulator of STING signaling that is dynamically repressed during viral infection.
Ritchie C, Li L. Mol Cell. 2024 Jul 11; 84(13):2423-2435.e5. Epub 2024 Jun 24.
PELI2 regulates early B-cell progenitor differentiation and related leukemia via the IL-7R expression. [Haematologica. 2024]
PELI2 regulates early B-cell progenitor differentiation and related leukemia via the IL-7R expression.
Xu Y, Zhou Q, Wang X, Zhang A, Qi W, Li Y, Zheng C, Guan J, Sun T, Li J, et al. Haematologica. 2024 Jun 1; 109(6):1800-1814. Epub 2024 Jun 1.
A Pellino-2 variant is associated with constitutive NLRP3 inflammasome activation in a family with ocular pterygium-digital keloid dysplasia. [FEBS Lett. 2023]
A Pellino-2 variant is associated with constitutive NLRP3 inflammasome activation in a family with ocular pterygium-digital keloid dysplasia.
Cristea I, Abarca H, Christensen Mellgren AE, Trubnykova M, Mehrasa R, Peters DJM, Houge G, Hennekam RCM, Rødahl E, Bruland O, et al. FEBS Lett. 2023 May; 597(9):1290-1299. Epub 2023 Feb 24.

RefSeq alternative splicing
See 13 reference mRNA sequence splice variants for the PELI2 gene.
RefSeq protein product
See the reference protein sequence for E3 ubiquitin-protein ligase pellino homolog 2 (NP_067078.1).

Protein
Protein sequence from Nucleotide coding region
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Nucleotide