Rattus norvegicus pyruvate dehydrogenase kinase 1 (Pdk1), mRNA

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Inhibition of the ubiquitin-proteasome system reduces the abundance of pyruvate dehydrogenase kinase 1 in cultured myotubes. [J Muscle Res Cell Motil. 2024]
Inhibition of the ubiquitin-proteasome system reduces the abundance of pyruvate dehydrogenase kinase 1 in cultured myotubes.
Kociper B, Škorja Milić N, Ogrizek I, Miš K, Pirkmajer S. J Muscle Res Cell Motil. 2024 Sep; 45(3):155-169. Epub 2024 Jul 31.
M(1) and M(2) mAChRs activate PDK1 and regulate PKC βI and ε and the exocytotic apparatus at the NMJ. [FASEB J. 2021]
M(1) and M(2) mAChRs activate PDK1 and regulate PKC βI and ε and the exocytotic apparatus at the NMJ.
Cilleros-Mañé V, Just-Borràs L, Polishchuk A, Durán M, Tomàs M, Garcia N, Tomàs JM, Lanuza MA. FASEB J. 2021 Jul; 35(7):e21724.
Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis. [Circ Res. 2020]
Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis.
Tian L, Wu D, Dasgupta A, Chen KH, Mewburn J, Potus F, Lima PDA, Hong Z, Zhao YY, Hindmarch CCT, et al. Circ Res. 2020 Jun 5; 126(12):1723-1745. Epub 2020 Mar 27.

RefSeq alternative splicing
See 3 reference mRNA sequence splice variants for the Pdk1 gene.
RefSeq protein product
See the reference protein sequence for pyruvate dehydrogenase kinase, isozyme 1 precursor (NP_446278.2).

Protein
Protein sequence from Nucleotide coding region
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Ensembl [Ensembl]
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pyruvate dehydrogenase kinase 1 [Guide to Pharmacology]
pyruvate dehydrogenase kinase 1
Guide to Pharmacology
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reagents
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reagent reviews [ExactAntigen/Labome]
reagent reviews
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Nucleotide