LOCUS NM_057373 3086 bp mRNA linear INV 26-DEC-2023
DEFINITION Drosophila melanogaster shaker cognate w, transcript variant A
(Shaw), mRNA.
ACCESSION NM_057373
VERSION NM_057373.3
DBLINK BioProject: PRJNA164
BioSample: SAMN02803731
KEYWORDS RefSeq.
SOURCE Drosophila melanogaster (fruit fly)
ORGANISM Drosophila melanogaster
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
REFERENCE 1 (bases 1 to 3086)
AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St
Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K.,
Strelets,V., Russo,S.M. and Gelbart,W.M.
CONSRTM FlyBase Consortium
TITLE Gene Model Annotations for Drosophila melanogaster: Impact of
High-Throughput Data
JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015)
PUBMED 26109357
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 3086)
AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St
Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B.,
Russo,S.M. and Gelbart,W.M.
CONSRTM FlyBase Consortium
TITLE Gene Model Annotations for Drosophila melanogaster: The
Rule-Benders
JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015)
PUBMED 26109356
REMARK Publication Status: Online-Only
REFERENCE 3 (bases 1 to 3086)
AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I.,
Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R.,
Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G.,
Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N.,
Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A.,
Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E.
TITLE The Release 6 reference sequence of the Drosophila melanogaster
genome
JOURNAL Genome Res 25 (3), 445-458 (2015)
PUBMED 25589440
REFERENCE 4 (bases 1 to 3086)
AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M.,
Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F.,
Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E.
TITLE Sequence finishing and mapping of Drosophila melanogaster
heterochromatin
JOURNAL Science 316 (5831), 1625-1628 (2007)
PUBMED 17569867
REFERENCE 5 (bases 1 to 3086)
AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H.
TITLE The Release 5.1 annotation of Drosophila melanogaster
heterochromatin
JOURNAL Science 316 (5831), 1586-1591 (2007)
PUBMED 17569856
REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325]
REFERENCE 6 (bases 1 to 3086)
AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D.,
Ashburner,M. and Anxolabehere,D.
TITLE Combined evidence annotation of transposable elements in genome
sequences
JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005)
PUBMED 16110336
REFERENCE 7 (bases 1 to 3086)
AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A.,
Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A.,
Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W.,
Celniker,S.E., Rubin,G.M. and Karpen,G.H.
TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun
assembly
JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002)
PUBMED 12537574
REFERENCE 8 (bases 1 to 3086)
AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J.,
Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E.,
Rubin,G.M., Ashburner,M. and Celniker,S.E.
TITLE The transposable elements of the Drosophila melanogaster
euchromatin: a genomics perspective
JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002)
PUBMED 12537573
REFERENCE 9 (bases 1 to 3086)
AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S.,
Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E.,
Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L.,
Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D.,
Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J.,
Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M.,
Rubin,G.M. and Lewis,S.E.
TITLE Annotation of the Drosophila melanogaster euchromatic genome: a
systematic review
JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002)
PUBMED 12537572
REFERENCE 10 (bases 1 to 3086)
AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W.,
Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E.,
Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M.,
Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S.,
Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M.,
Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W.,
Gibbs,R.A. and Rubin,G.M.
TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila
melanogaster euchromatic genome sequence
JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002)
PUBMED 12537568
REFERENCE 11 (bases 1 to 3086)
AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D.,
Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F.,
George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N.,
Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X.,
Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D.,
Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L.,
Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D.,
Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M.,
Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S.,
Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P.,
Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A.,
Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B.,
Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I.,
Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S.,
Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C.,
Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S.,
Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z.,
Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J.,
Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J.,
Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z.,
Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C.,
Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A.,
Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C.,
McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C.,
Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L.,
Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K.,
Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S.,
Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K.,
Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I.,
Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C.,
Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R.,
Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A.,
Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT,
Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F.,
Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H.,
Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O.,
Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C.
TITLE The genome sequence of Drosophila melanogaster
JOURNAL Science 287 (5461), 2185-2195 (2000)
PUBMED 10731132
REFERENCE 12 (bases 1 to 3086)
AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R.,
Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R.,
Smith,E., Yu,C. and Rubin,G.
CONSRTM Berkeley Drosophila Genome Project
TITLE Drosophila melanogaster release 4 sequence
JOURNAL Unpublished
REFERENCE 13 (bases 1 to 3086)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 14 (bases 1 to 3086)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 15 (bases 1 to 3086)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (10-NOV-2022) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 16 (bases 1 to 3086)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 17 (bases 1 to 3086)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 18 (bases 1 to 3086)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 19 (bases 1 to 3086)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 20 (bases 1 to 3086)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 21 (bases 1 to 3086)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (07-OCT-2015) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 22 (bases 1 to 3086)
AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R.,
Park,S., Svirskas,R. and Karpen,G.
TITLE Direct Submission
JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project,
Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne
Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA
REMARK Direct Submission
REFERENCE 23 (bases 1 to 3086)
AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S.,
Svirskas,R. and Rubin,G.
TITLE Direct Submission
JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project,
Lawrence Berkeley National Laboratory, One Cyclotron Road, MS
64-121, Berkeley, CA 94720, USA
REMARK Direct Submission
REFERENCE 24 (bases 1 to 3086)
AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H.
CONSRTM Drosophila Heterochromatin Genome Project
TITLE Direct Submission
JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project,
Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron
Road, Mailstop 64-121, Berkeley, CA 94720, USA
REFERENCE 25 (bases 1 to 3086)
AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J.
TITLE Direct Submission
JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive,
Rockville, MD 20850, USA
COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This
record is derived from an annotated genomic sequence (NT_033779).
On Jan 16, 2013 this sequence version replaced NM_057373.2.
##Genome-Annotation-Data-START##
Annotation Provider :: FlyBase
Annotation Status :: Full annotation
Annotation Version :: Release 6.54
URL :: http://flybase.org
##Genome-Annotation-Data-END##
FEATURES Location/Qualifiers
source 1..3086
/organism="Drosophila melanogaster"
/mol_type="mRNA"
/db_xref="taxon:7227"
/chromosome="2L"
/genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2]
bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]"
gene 1..3086
/gene="Shaw"
/locus_tag="Dmel_CG2822"
/gene_synonym="CG15419; CG2822; Dmel\CG2822; dShaw;
dShaw2; Kv3; Kv3.1; K[[v]]3; shaw; Shaw2"
/note="Shaker cognate w"
/map="24C1-24C2"
/db_xref="FLYBASE:FBgn0003386"
/db_xref="GeneID:33599"
CDS 458..1954
/gene="Shaw"
/locus_tag="Dmel_CG2822"
/gene_synonym="CG15419; CG2822; Dmel\CG2822; dShaw;
dShaw2; Kv3; Kv3.1; K[[v]]3; shaw; Shaw2"
/note="CG2822 gene product from transcript CG2822-RA;
CG2822-PA; Shaw-PA"
/codon_start=1
/product="shaker cognate w, isoform A"
/protein_id="NP_476721.1"
/db_xref="FLYBASE:FBpp0088331"
/db_xref="GeneID:33599"
/db_xref="FLYBASE:FBgn0003386"
/translation="MNLINMDSENRVVLNVGGIRHETYKATLKKIPATRLSRLTEALA
NYDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPC
CWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRI
WSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSNGW
FLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFY
IDLVLQRFASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVF
FLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMF
VGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPRQPRLPGA
PGGVSGCGTPGSGPHSGPMGSGGTGPRRMNNKTKDLVSPKSDMAFSFD"
ORIGIN
1 tcagtttgtt aaatcgcctc gaacggttcg gaacgcgcgc gctcgaagag atcggacggc
61 caactccccg gaaagaaaga aaaatagtgg aaggaggcgc ccccacaagg cgaacgagtg
121 tagtgtagta gtgaaatagt cctcgattta gtttacccct tttccgcaat tttcaccaag
181 cccgaaacat tggatttcct gtgattttcc gacttttcct gcgaccagac tccccaaaat
241 ccccagtatc ggaactatgt ttatgggcag agcgcaacga ggccgcagga tgagagaata
301 gcggcatgtt gtccaactca gccccaacgt atggtggtac taggtcctga ggcctgatcc
361 ccattgggtg ccgaagagtg gatcgaagtg gtgccttgac ggagtggtag gcataactgc
421 ataaatcgtg ggcaaggaca acgaaaagca ttcagccatg aatctgatca acatggactc
481 ggaaaacagg gtggtgctca atgtgggtgg cattaggcac gaaacctaca aggccacgct
541 gaagaagatt ccggctacgc gattatcgcg attaacagag gcgctggcca actatgatcc
601 gatactgaat gagtacttct ttgatcggca tccgggcgtc ttcgcacaag tgctcaacta
661 ttacagaact ggaaagctgc attatcccac ggatgtgtgc ggtccgctgt ttgaggagga
721 attggagttc tggggcctag actcgaacca agtggagccc tgctgttgga tgacctacac
781 acagcatcgc gacacccagg aaaccctagc cgtactcgat cgtctcgatc tggatacgga
841 aaaaccgtcc gaagaggaat tggcacgcaa attcggcttc gaggaggact actacaaagg
901 cacaatatcc tggtggcagg aaatgaagcc gcgcatttgg tccttgttcg atgagcccta
961 cagttccaat gcagccaaga ctattggcgt ggtttcggtg ttcttcatct gcatttcgat
1021 cctgtcgttc tgcctgaaga cccatcccga tatgcgggta cccatcgtcc ggaacattac
1081 agtgaaaact gcgaatggaa gtaatggctg gtttttggac aaaacgcaga ccaatgcgca
1141 catagccttc ttctatatcg aatgcgtgtg caatgcctgg tttacctttg aaatattggt
1201 gcgctttatc tcatcgccga acaagtggga gttcatcaag tcatctgtta acatcataga
1261 ctacatagcg acgcttagtt tttatatcga tctagtgctt cagcggttcg catcgcacct
1321 ggagaacgct gacatcctcg agttcttctc gatcatccgc atcatgcgtc tgttcaagct
1381 gacgcgccac tcgtccggac tgaagatcct gatccagacg ttccgggcct cggccaagga
1441 gctgaccctg ctggtgttct tcctcgtcct gggcatcgtg atcttcgcca gccttgtcta
1501 ctacgcggag cgcatccagc ccaatccgca caacgacttc aacagcatac cgctgggcct
1561 gtggtgggcc ctggtcacaa tgaccaccgt cggctacggc gacatggccc ccaaaaccta
1621 catcggcatg ttcgtgggcg ccctctgcgc cctggccggc gtactaacca tcgcactgcc
1681 agtgcccgtc atcgtcagca acttcgccat gtactactcg cacacgcagg ccagggccaa
1741 actgccaaag aagcggagac gagtgcttcc cgtcgagcag ccgcgccagc ccagactgcc
1801 aggtgcccct ggtggtgtca gtggttgcgg taccccgggc tcgggtcccc actccggtcc
1861 catgggatcc ggcggtactg gaccacgtcg catgaacaat aaaacaaagg acctggtcag
1921 ccccaagtca gatatggcct tcagtttcga ctaaaacaga aaacagaaca gaaccagaaa
1981 gatattttgt aatttgataa gccagctcaa aacacagtat aaaaaaaaaa aacaagaaaa
2041 actcggcaac aaaatcgaaa aaaaaaatcg aaaccaaatc aaaacgaaac ctcagttata
2101 tacgaaataa gaaatccccg gttcgttcat ctatcatcta actatcagct aaccaaaact
2161 cggactctgc tgggcggttg ctcaactttt cgcaggtccg ctgggcgcaa gcattgtggc
2221 catgagtccc cggacaatgc tggatctcaa tcctgccctg gcgatgggca agcctacgtt
2281 tcagccccgt atacccaccc ccctggcagc cacgccccct ccccccgtga gttccgctgg
2341 ggggatgaca gcgtctggaa ttggaactac ttcagccact ggagccacta gtgcaccaca
2401 accagcaaca ccactaccca gcattgcggt gtccaccaca gcgagtgtgg gcaaggattt
2461 gggcatctcg accaccacca ccacggccca ggagaccagc aagaaggcct tcctctaaag
2521 gagcagccca gccaaggatt cagccacctg ctatttatat ttatccacga tccccatatc
2581 ctccaataag caatatctat tcgatgtcat acagagcctt cgcatacgta ttcactaaga
2641 acaaagatgg tgtgtttcaa agttagcaaa aggatcctaa cctactcgta tcacttgaga
2701 tcgtctttgt tttcctcata tcatcacaca ctgtgtttcg caaagcctca tatcgaaaaa
2761 tatcgaaatg aatatcatat attcacgaac gagtctacaa tggatcagaa ttagctggag
2821 atcaatctta aatcaaatat cgattgtgat gctatattat gaaaagtatt ctttgatttc
2881 agaaggggtt taggatatta ctctatataa gccatttgac tgttattata tattagttgc
2941 ttacttttat atatcgaatc ctatgtaata tctcacactg aaatgaaaag gccaatatta
3001 aagcaatact ttggttcaag accaattata cacctagcta aaaattacca ttctgtttaa
3061 tccagcaata aaatatgttt ttaacc
//