LOCUS NM_120360 1659 bp mRNA linear PLN 20-OCT-2022
DEFINITION Arabidopsis thaliana Spo11/DNA topoisomerase VI, subunit A protein
(RHL2), mRNA.
ACCESSION NM_120360
VERSION NM_120360.4
DBLINK BioProject: PRJNA116
BioSample: SAMN03081427
KEYWORDS RefSeq.
SOURCE Arabidopsis thaliana (thale cress)
ORGANISM Arabidopsis thaliana
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae;
Pentapetalae; rosids; malvids; Brassicales; Brassicaceae;
Camelineae; Arabidopsis.
REFERENCE 1 (bases 1 to 1659)
AUTHORS Tabata,S., Kaneko,T., Nakamura,Y., Kotani,H., Kato,T., Asamizu,E.,
Miyajima,N., Sasamoto,S., Kimura,T., Hosouchi,T., Kawashima,K.,
Kohara,M., Matsumoto,M., Matsuno,A., Muraki,A., Nakayama,S.,
Nakazaki,N., Naruo,K., Okumura,S., Shinpo,S., Takeuchi,C., Wada,T.,
Watanabe,A., Yamada,M., Yasuda,M., Sato,S., de la Bastide,M.,
Huang,E., Spiegel,L., Gnoj,L., O'Shaughnessy,A., Preston,R.,
Habermann,K., Murray,J., Johnson,D., Rohlfing,T., Nelson,J.,
Stoneking,T., Pepin,K., Spieth,J., Sekhon,M., Armstrong,J.,
Becker,M., Belter,E., Cordum,H., Cordes,M., Courtney,L.,
Courtney,W., Dante,M., Du,H., Edwards,J., Fryman,J., Haakensen,B.,
Lamar,E., Latreille,P., Leonard,S., Meyer,R., Mulvaney,E.,
Ozersky,P., Riley,A., Strowmatt,C., Wagner-McPherson,C., Wollam,A.,
Yoakum,M., Bell,M., Dedhia,N., Parnell,L., Shah,R., Rodriguez,M.,
See,L.H., Vil,D., Baker,J., Kirchoff,K., Toth,K., King,L.,
Bahret,A., Miller,B., Marra,M., Martienssen,R., McCombie,W.R.,
Wilson,R.K., Murphy,G., Bancroft,I., Volckaert,G., Wambutt,R.,
Dusterhoft,A., Stiekema,W., Pohl,T., Entian,K.D., Terryn,N.,
Hartley,N., Bent,E., Johnson,S., Langham,S.A., McCullagh,B.,
Robben,J., Grymonprez,B., Zimmermann,W., Ramsperger,U., Wedler,H.,
Balke,K., Wedler,E., Peters,S., van Staveren,M., Dirkse,W.,
Mooijman,P., Lankhorst,R.K., Weitzenegger,T., Bothe,G., Rose,M.,
Hauf,J., Berneiser,S., Hempel,S., Feldpausch,M., Lamberth,S.,
Villarroel,R., Gielen,J., Ardiles,W., Bents,O., Lemcke,K.,
Kolesov,G., Mayer,K., Rudd,S., Schoof,H., Schueller,C.,
Zaccaria,P., Mewes,H.W., Bevan,M. and Fransz,P.
CONSRTM Kazusa DNA Research Institute; Cold Spring Harbor and Washington
University in St Louis Sequencing Consortium; European Union
Arabidopsis Genome Sequencing Consortium
TITLE Sequence and analysis of chromosome 5 of the plant Arabidopsis
thaliana
JOURNAL Nature 408 (6814), 823-826 (2000)
PUBMED 11130714
REFERENCE 2 (bases 1 to 1659)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (19-OCT-2022) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 3 (bases 1 to 1659)
AUTHORS Krishnakumar,V., Cheng,C.-Y., Chan,A.P., Schobel,S., Kim,M.,
Ferlanti,E.S., Belyaeva,I., Rosen,B.D., Micklem,G., Miller,J.R.,
Vaughn,M. and Town,C.D.
TITLE Direct Submission
JOURNAL Submitted (17-MAY-2016) Plant Genomics, J. Craig Venter Institute,
9704 Medical Center Dr, Rockville, MD 20850, USA
REMARK Protein update by submitter
REFERENCE 4 (bases 1 to 1659)
AUTHORS Swarbreck,D., Lamesch,P., Wilks,C. and Huala,E.
CONSRTM TAIR
TITLE Direct Submission
JOURNAL Submitted (18-FEB-2011) Department of Plant Biology, Carnegie
Institution, 260 Panama Street, Stanford, CA, USA
COMMENT REVIEWED REFSEQ: This record has been curated by TAIR and Araport.
This record is derived from an annotated genomic sequence
(NC_003076).
On Sep 12, 2016 this sequence version replaced NM_120360.3.
FEATURES Location/Qualifiers
source 1..1659
/organism="Arabidopsis thaliana"
/mol_type="mRNA"
/db_xref="taxon:3702"
/chromosome="5"
/ecotype="Columbia"
gene 1..1659
/gene="RHL2"
/locus_tag="AT5G02820"
/gene_synonym="BIN5; BRASSINOSTEROID INSENSITIVE 5;
F9G14.130; F9G14_130; ROOT HAIRLESS 2; SPO11-3"
/note="Involved in the patterning and shape of leaf
trichomes. Encodes the DNA topoisomerase VI SPO11-3,
involved in endoreduplication"
/db_xref="Araport:AT5G02820"
/db_xref="GeneID:831314"
/db_xref="TAIR:AT5G02820"
CDS 105..1388
/gene="RHL2"
/locus_tag="AT5G02820"
/gene_synonym="BIN5; BRASSINOSTEROID INSENSITIVE 5;
F9G14.130; F9G14_130; ROOT HAIRLESS 2; SPO11-3"
/inference="Similar to RNA sequence,
EST:INSD:DR350099.1,INSD:AV522732.1,INSD:AU228636.1,
INSD:BP779675.1,INSD:EL234507.1,INSD:AU229543.1,
INSD:BP794826.1,INSD:BP601235.1,INSD:BP783143.1,
INSD:BP792524.1,INSD:EG486686.1,INSD:ES182059.1,
INSD:EL996477.1,INSD:DR350098.1,INSD:BG459183.1,
INSD:AV542155.1,INSD:AI995290.1,INSD:BP613574.1,
INSD:AV523333.1,INSD:BP778108.1,INSD:AV542101.1"
/inference="similar to RNA sequence,
mRNA:INSD:AJ297842.1,INSD:BX832591.1,INSD:AF323679.1,
INSD:BX831096.1,INSD:BX830004.1,INSD:BT028966.1,
INSD:BX830246.1"
/note="ROOT HAIRLESS 2 (RHL2); CONTAINS InterPro DOMAIN/s:
Spo11/DNA topoisomerase VI, subunit A, N-terminal
(InterPro:IPR013049), DNA topoisomerase VI, subunit A
(InterPro:IPR004085), Spo11/DNA topoisomerase VI, subunit
A (InterPro:IPR002815); BEST Arabidopsis thaliana protein
match is: Spo11/DNA topoisomerase VI, subunit A protein
(TAIR:AT3G13170.1); Has 936 Blast hits to 932 proteins in
314 species: Archae - 223; Bacteria - 16; Metazoa - 170;
Fungi - 119; Plants - 152; Viruses - 0; Other Eukaryotes -
256 (source: NCBI BLink)."
/codon_start=1
/product="Spo11/DNA topoisomerase VI, subunit A protein"
/protein_id="NP_195902.1"
/db_xref="GeneID:831314"
/db_xref="TAIR:AT5G02820"
/db_xref="Araport:AT5G02820"
/translation="MADKKKRKRSKDDEAEELPFKSILESDDVITELLKSYISSSIKA
AAGAGGASSSSSKPLTLADLSLSSSCREVADLSLSSVQTEIETVIVQIARSILAGDGF
SFSVPSRAASNQLYVPELDRIVLKDKSTLRPFASVSSVRKTTITTRILALIHQLCLRN
IHVTKRDLFYTDVKLFQDQTQSDAVLDDVSCMLGCTRSSLNVIAAEKGVVVGRLIFSD
NGDMIDCTKMGMGGKAIPPNIDRVGDMQSDAMFILLVEKDAAYMRLAEDRFYNRFPCI
IVTAKGQPDVATRLFLRKMKMELKLPVLALVDSDPYGLKILSVYGCGSKNMSYDSANL
TTPDIKWLGIRPSDLDKYKIPEQCRLPMTEQDIKTGKDMLEEDFVKKNPGWVEELNLM
VKTKQKAEIQALSSFGFQYLSEVYLPLKLQQQDWL"
ORIGIN
1 ataacattca cgagatacgt tgacctaaag ggtaaatttt cccgccattg ttagtaccag
61 aactctctgg gccgccgcgt ctccgtcgtc gtggctatct acagatggcg gataagaaga
121 agcgaaagcg atcaaaagat gacgaggcgg aggaacttcc tttcaaaagc attctggaat
181 cagacgacgt tatcacggag cttctcaaat cgtatatttc ctcttctatc aaagccgccg
241 ccggagccgg cggtgcctcc tcctcttcat cgaaacctct aaccctagct gacctctctc
301 tatcatcttc ctgtcgtgaa gtcgcagatc tctcactctc ctccgtgcag acagagatag
361 agacagtcat cgtccagatc gcccgttcta ttctcgccgg tgatggcttc tccttcagtg
421 ttccttcacg cgccgcctcg aatcagctgt atgttcctga gctcgaccgt atagtgctaa
481 aagacaaatc taccctccgt ccatttgcct ccgtttcttc tgtcaggaaa accaccatca
541 ccactcgtat cctcgccctt atccaccaac tctgcctcag gaacattcac gttactaagc
601 gtgatctctt ctacaccgac gttaagcttt tccaggacca gacacagagt gatgctgtgt
661 tggatgatgt ctcatgtatg ctcggttgca caaggtcaag tctcaatgtc attgcagcag
721 agaaaggtgt ggtggtggga aggcttatat tcagtgacaa tggagacatg atagattgca
781 caaagatggg aatgggtggg aaagccattc caccaaacat tgaccgggtt ggagatatgc
841 agagtgatgc tatgttcata ctcttagttg aaaaagatgc agcttatatg aggttagctg
901 aagacagatt ctataaccgg ttcccttgta tcatcgtgac tgcaaaaggc cagcctgatg
961 tagctacaag gctcttcttg aggaaaatga aaatggagct taagcttccg gtacttgcct
1021 tggtggatag tgatccttac ggattgaaga tcttgtcggt gtatggatgt gggtcgaaga
1081 acatgtcata tgatagtgca aacttgacta cgcctgatat taagtggctt ggaattaggc
1141 cgagtgattt ggacaagtat aagatacctg aacagtgtag gttgccgatg actgagcagg
1201 atattaagac cgggaaggat atgctagagg aggatttcgt gaagaaaaat cccgggtggg
1261 tcgaggaact taacctgatg gtgaaaacga agcaaaaggc tgagattcag gcgttgagct
1321 cttttggttt ccagtattta tcggaagttt acttgcccct gaaactgcag cagcaggatt
1381 ggctctgata atcaggtttc ttcctgatca attagataga ccaacaagtg tactctacaa
1441 atttcgaatt tttgataatg caattgcctg tttcttagca tgtgaattat tattgcaaag
1501 atcgaaattt ggttttaaat ttatggttga atctacacag aactggaaag atagctgtca
1561 gatgattatt tagaagacaa ctcttttgtt tatttagaag attgtataca atatgatggg
1621 cattgagatg atatgcaatc tttccccatt cttttctgc
//