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Drosophila melanogaster pod1 coronin (pod1), transcript variant E, mRNA

NCBI Reference Sequence: NM_167094.2

FASTA Graphics 

LOCUS       NM_167094               5806 bp    mRNA    linear   INV 26-DEC-2023
DEFINITION  Drosophila melanogaster pod1 coronin (pod1), transcript variant E,
            mRNA.
ACCESSION   NM_167094
VERSION     NM_167094.2
DBLINK      BioProject: PRJNA164
            BioSample: SAMN02803731
KEYWORDS    RefSeq.
SOURCE      Drosophila melanogaster (fruit fly)
  ORGANISM  Drosophila melanogaster
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
REFERENCE   1  (bases 1 to 5806)
  AUTHORS   Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St
            Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K.,
            Strelets,V., Russo,S.M. and Gelbart,W.M.
  CONSRTM   FlyBase Consortium
  TITLE     Gene Model Annotations for Drosophila melanogaster: Impact of
            High-Throughput Data
  JOURNAL   G3 (Bethesda) 5 (8), 1721-1736 (2015)
   PUBMED   26109357
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5806)
  AUTHORS   Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St
            Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B.,
            Russo,S.M. and Gelbart,W.M.
  CONSRTM   FlyBase Consortium
  TITLE     Gene Model Annotations for Drosophila melanogaster: The
            Rule-Benders
  JOURNAL   G3 (Bethesda) 5 (8), 1737-1749 (2015)
   PUBMED   26109356
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5806)
  AUTHORS   Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I.,
            Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R.,
            Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G.,
            Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N.,
            Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A.,
            Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E.
  TITLE     The Release 6 reference sequence of the Drosophila melanogaster
            genome
  JOURNAL   Genome Res 25 (3), 445-458 (2015)
   PUBMED   25589440
REFERENCE   4  (bases 1 to 5806)
  AUTHORS   Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M.,
            Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F.,
            Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E.
  TITLE     Sequence finishing and mapping of Drosophila melanogaster
            heterochromatin
  JOURNAL   Science 316 (5831), 1625-1628 (2007)
   PUBMED   17569867
REFERENCE   5  (bases 1 to 5806)
  AUTHORS   Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H.
  TITLE     The Release 5.1 annotation of Drosophila melanogaster
            heterochromatin
  JOURNAL   Science 316 (5831), 1586-1591 (2007)
   PUBMED   17569856
  REMARK    Erratum:[Science. 2007 Sep 7;317(5843):1325]
REFERENCE   6  (bases 1 to 5806)
  AUTHORS   Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D.,
            Ashburner,M. and Anxolabehere,D.
  TITLE     Combined evidence annotation of transposable elements in genome
            sequences
  JOURNAL   PLoS Comput Biol 1 (2), 166-175 (2005)
   PUBMED   16110336
REFERENCE   7  (bases 1 to 5806)
  AUTHORS   Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A.,
            Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A.,
            Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W.,
            Celniker,S.E., Rubin,G.M. and Karpen,G.H.
  TITLE     Heterochromatic sequences in a Drosophila whole-genome shotgun
            assembly
  JOURNAL   Genome Biol 3 (12), RESEARCH0085 (2002)
   PUBMED   12537574
REFERENCE   8  (bases 1 to 5806)
  AUTHORS   Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J.,
            Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E.,
            Rubin,G.M., Ashburner,M. and Celniker,S.E.
  TITLE     The transposable elements of the Drosophila melanogaster
            euchromatin: a genomics perspective
  JOURNAL   Genome Biol 3 (12), RESEARCH0084 (2002)
   PUBMED   12537573
REFERENCE   9  (bases 1 to 5806)
  AUTHORS   Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S.,
            Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E.,
            Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L.,
            Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D.,
            Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J.,
            Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M.,
            Rubin,G.M. and Lewis,S.E.
  TITLE     Annotation of the Drosophila melanogaster euchromatic genome: a
            systematic review
  JOURNAL   Genome Biol 3 (12), RESEARCH0083 (2002)
   PUBMED   12537572
REFERENCE   10 (bases 1 to 5806)
  AUTHORS   Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W.,
            Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E.,
            Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M.,
            Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S.,
            Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M.,
            Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W.,
            Gibbs,R.A. and Rubin,G.M.
  TITLE     Finishing a whole-genome shotgun: release 3 of the Drosophila
            melanogaster euchromatic genome sequence
  JOURNAL   Genome Biol 3 (12), RESEARCH0079 (2002)
   PUBMED   12537568
REFERENCE   11 (bases 1 to 5806)
  AUTHORS   Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D.,
            Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F.,
            George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N.,
            Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X.,
            Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D.,
            Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L.,
            Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D.,
            Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M.,
            Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S.,
            Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P.,
            Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A.,
            Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B.,
            Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I.,
            Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S.,
            Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C.,
            Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S.,
            Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z.,
            Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J.,
            Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J.,
            Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z.,
            Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C.,
            Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A.,
            Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C.,
            McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C.,
            Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L.,
            Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K.,
            Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S.,
            Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K.,
            Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I.,
            Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C.,
            Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R.,
            Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A.,
            Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT,
            Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F.,
            Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H.,
            Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O.,
            Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C.
  TITLE     The genome sequence of Drosophila melanogaster
  JOURNAL   Science 287 (5461), 2185-2195 (2000)
   PUBMED   10731132
REFERENCE   12 (bases 1 to 5806)
  AUTHORS   Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R.,
            Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R.,
            Smith,E., Yu,C. and Rubin,G.
  CONSRTM   Berkeley Drosophila Genome Project
  TITLE     Drosophila melanogaster release 4 sequence
  JOURNAL   Unpublished
REFERENCE   13 (bases 1 to 5806)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-DEC-2023) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   14 (bases 1 to 5806)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (13-DEC-2023) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   15 (bases 1 to 5806)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2022) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   16 (bases 1 to 5806)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-2020) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   17 (bases 1 to 5806)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (22-APR-2019) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   18 (bases 1 to 5806)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (24-MAY-2018) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   19 (bases 1 to 5806)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (07-DEC-2016) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   20 (bases 1 to 5806)
  AUTHORS   Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R.,
            Park,S., Svirskas,R. and Karpen,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2006) Berkeley Drosophila Genome Project,
            Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne
            Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA
  REMARK    Direct Submission
REFERENCE   21 (bases 1 to 5806)
  AUTHORS   Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S.,
            Svirskas,R. and Rubin,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2006) Berkeley Drosophila Genome Project,
            Lawrence Berkeley National Laboratory, One Cyclotron Road, MS
            64-121, Berkeley, CA 94720, USA
  REMARK    Direct Submission
REFERENCE   22 (bases 1 to 5806)
  AUTHORS   Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H.
  CONSRTM   Drosophila Heterochromatin Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project,
            Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron
            Road, Mailstop 64-121, Berkeley, CA 94720, USA
REFERENCE   23 (bases 1 to 5806)
  AUTHORS   Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive,
            Rockville, MD 20850, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by FlyBase. This
            record is derived from an annotated genomic sequence (NC_004354).
            
            On May 8, 2012 this sequence version replaced NM_167094.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: FlyBase
            Annotation Status   :: Full annotation
            Annotation Version  :: Release 6.54
            URL                 :: http://flybase.org
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5806
                     /organism="Drosophila melanogaster"
                     /mol_type="mRNA"
                     /db_xref="taxon:7227"
                     /chromosome="X"
                     /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2]
                     bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]"
     gene            1..5806
                     /gene="pod1"
                     /locus_tag="Dmel_CG4532"
                     /gene_synonym="BcDNA:LD08951; BEST:LD37601; CG4532;
                     Dmel\CG4532; dmPod; dpod1; Dpod1; DPod1; pod-1; Pod-1;
                     POD-1; Pod1"
                     /note="pod1 coronin"
                     /map="6D2-6D3"
                     /db_xref="FLYBASE:FBgn0029903"
                     /db_xref="GeneID:31620"
     CDS             324..3548
                     /gene="pod1"
                     /locus_tag="Dmel_CG4532"
                     /gene_synonym="BcDNA:LD08951; BEST:LD37601; CG4532;
                     Dmel\CG4532; dmPod; dpod1; Dpod1; DPod1; pod-1; Pod-1;
                     POD-1; Pod1"
                     /note="CG4532 gene product from transcript CG4532-RE;
                     CG4532-PE; pod1-PE; POD-1/coronin"
                     /codon_start=1
                     /product="pod1 coronin, isoform E"
                     /protein_id="NP_727128.1"
                     /db_xref="FLYBASE:FBpp0070929"
                     /db_xref="GeneID:31620"
                     /db_xref="FLYBASE:FBgn0029903"
                     /translation="MAWRFKASKYKNAAPIVPKAEACVREICVGSYQTYGNNIAASGA
                     FMAFNWEHTGSSVAVLPLDDCGRKSKTMPLLHGHTDTVTDLKFSPFHDGLLATASQDC
                     LVKIWHIPEKGLEQSLSDPEAIFSHKQRRVETVGFHPTADGLMYSTAAGCVALFDLST
                     QKEIFSNNEHPEVIQSASWREDGSVLATSCKDKNVRIFDPRAAGSPIQLTAESHQSIK
                     DSRVVWLGNQHRILTTGFDAARLRQVIIRDVRNFNTPEKTLELDCSTGILMPLFDPDT
                     NMLFLAGKGDTTINYLEITDKDPYLIEGLRHTGEQTKGACLVPKRALKVMEAEVNRVL
                     QLTSNMVIPIMYQVPRKTYRDFHADLYPETTGYKTELVAGEWLNGSNQAVPKMSLDPA
                     KREHGDEPIIPRLGPKPFSSTTGDVSFDKVFAVPLAPGSHENISNVGQDSGVEMTPAQ
                     GAKPDLIVEIEIKKKHEREPAVSGNGVQKSLTTSERRKIFEQNSESSENSTEGEDRTD
                     ADLRRNCTSRSSFAERRRIYENRSKSQVDEKPQSPVPLRREHSKVEPLKPNQQQQQQG
                     NVIDTKRISVPEGKLMEEHRRGNGAGLKKSATEAAFSAASTKRTSTVFGKVSKFRHLK
                     GTPGHKSTHIENLRNLSRQIPGECNGFHANQERVAVPLSGPGGKIAIFELSRPGRLPD
                     GVIPSLVNGSNIMDFQWDPFDAQRLAVACDDGIVKIWHIEAGGLSEPTNTPAGELTAH
                     LDKIYFIRFHPLAADVLLTASYDMTIKLWDLRTMTEKCSLSGHTDQIFDFAWSPCGRL
                     GATVCKDGKIRVYNPRKSETPIREGNGPVGTRGARITWALEGHYIVCTGFDKVSERQI
                     SVYNAQKLSAPLNTASLDVSPSILIPFYDEDSSTLFVTGKGDSTIYCYEITDEEPYIC
                     PLSHHRCTSLHQGLSFLTKNHCDVASVEFSKAYRLTNTTIEPLSFTVPRIKSELFQDD
                     LFPPTRITWSATLSSEDWFASNDKAAPKVSLKPEGMETLSSIQQVPAQPVKKPDHPQF
                     GGQKSEYEINKQQEIQKSVSARMEFTTKLEQDDMEGVDENEWQE"
ORIGIN      
        1 ggtcgggttg gctggctggc tcatccggct ttggtggaca ccattcttgt ccagctttct
       61 cttttcaata gacgtatcgc cgcaatagca aaaacgaaac tctgaaacgg agcagcggag
      121 cggagagcga agcgcaagag agcgactgag agggagccac cggactagtg acactcgacc
      181 atcaggcatc aagcatcggg catatacaat ccacaatcga ctctctacac tcgagcagag
      241 aacgtccata tccatatcca catccgcatc ggatcgccat cacatcggat cgaagccctc
      301 ccagctcaac caagtagcca accatggcct ggcgattcaa ggcttccaag tacaaaaatg
      361 ccgcacccat tgtgcccaag gcggaggcat gcgtccgcga gatctgcgtg ggcagctacc
      421 agacgtacgg taacaacatc gccgcctccg gcgccttcat ggccttcaac tgggagcaca
      481 ccgggtccag cgtcgctgtc ctcccgctgg acgactgcgg ccggaagagc aagaccatgc
      541 cgctgctcca tggacacacg gacacagtga cggaccttaa gttctccccg ttccacgacg
      601 ggctgctggc caccgcctcg caggattgcc tggtcaagat ctggcacata ccggaaaaag
      661 gtctggagca gtcgctttcc gatccggagg caatcttctc acacaagcag agacgcgtag
      721 agacagtggg cttccatcca acagcagatg gtttgatgta ctccacagcc gccggctgcg
      781 tggctctctt cgatctcagc actcaaaagg agatattctc gaacaatgag caccccgagg
      841 tgatacagtc ggccagttgg cgcgaggacg gttctgtttt ggccaccagt tgcaaggata
      901 agaatgtgcg aatcttcgat ccccgtgccg ctggttcacc catccagctg actgctgaat
      961 cgcatcagag catcaaggat tcgcgggtgg tgtggttagg caatcagcat cgcatcctga
     1021 ccactggctt cgatgcggcc cgcctgcgac aggtgatcat ccgtgatgtg cgcaacttca
     1081 acactccaga gaaaactctc gaactggact gctcgacggg catattgatg cccctcttcg
     1141 atcccgacac caatatgctt ttcctagccg gaaagggtga cacaaccatt aactatttgg
     1201 agattacgga caaggatccg tatttgattg agggcttgcg tcatactggc gagcagacga
     1261 agggagcttg tctcgtgccc aagcgggcac ttaaagtcat ggaagcagag gttaaccggg
     1321 tgttgcaatt gacctccaac atggtcatac ccatcatgta ccaggtgccc agaaagacat
     1381 accgtgattt ccacgccgat ctatatccgg agaccactgg ctacaagaca gaactggtgg
     1441 ccggcgagtg gctaaatggc agcaaccagg cggtgcccaa gatgagcctt gatcccgcca
     1501 agcgtgagca tggcgatgag ccaattattc cacgtttggg tcccaagccc ttctccagca
     1561 ccacaggtga cgtttcgttt gacaaggtgt tcgccgttcc cttggcaccg ggatcccacg
     1621 agaatatctc gaacgtgggt caggacagcg gagtggagat gacaccagct cagggagcca
     1681 aaccggatct cattgtggaa atcgaaatta aaaagaaaca cgaaagggaa cctgctgtgt
     1741 ccggaaatgg agtccagaag tcactgacca cttcggagcg ccgtaagata ttcgagcaga
     1801 actctgagtc atcggagaac tcgacggagg gggaagatcg cacggatgcg gatctgcgaa
     1861 gaaactgcac ctccaggagc agctttgccg agcgacggcg catatacgag aatcgttcca
     1921 agagtcaggt ggacgagaag cctcagtcgc cagtgccatt acgtcgcgag cactccaaag
     1981 tggagccgct gaagcccaac caacagcagc agcagcaggg caatgtgatc gacaccaagc
     2041 gcatctctgt tccagagggc aaattaatgg aggagcatcg ccgcggaaat ggcgctggac
     2101 tcaagaagtc cgccactgag gcggctttta gcgctgccag caccaagcgc acttccaccg
     2161 tcttcggcaa ggtgtccaag ttcaggcact tgaagggcac acccggtcac aagtccacgc
     2221 acatcgagaa cttgcgcaat ctaagtcgcc agattccggg cgaatgcaat ggcttccacg
     2281 ctaaccagga gcgagttgcc gtgccacttt cggggcccgg cggcaagata gccatctttg
     2341 agttgagccg ccctggacgg ttgcccgatg gtgtgattcc gtcacttgtg aacggcagca
     2401 acatcatgga cttccagtgg gatccgttcg atgcccagcg attggctgtg gcatgcgacg
     2461 atggcattgt aaagatctgg catattgaag ccggtggatt gagtgagccg acaaacacac
     2521 ctgccggcga gctaaccgct catctggaca agatttactt catacgcttc cacccgctgg
     2581 ctgctgatgt tctgttaacc gccagctacg atatgaccat caagctgtgg gatttgcgca
     2641 ccatgaccga gaaatgctcg ctttcggggc atacagatca aatctttgac ttcgcctgga
     2701 gtccctgcgg ccgattgggc gccaccgtgt gcaaggatgg caagattagg gtgtacaacc
     2761 caaggaaatc ggagacaccc atacgggagg gcaatggacc ggtcggtact cgtggagctc
     2821 ggatcacctg ggcgttggag ggacattaca tcgtctgcac tggttttgac aaggtttcgg
     2881 agcgacagat cagcgtgtac aatgcacaaa agttgtccgc cccattgaac actgccagtt
     2941 tggatgtctc accctccata ctgattccat tctatgacga agatagctcc acactgtttg
     3001 ttacgggcaa gggtgactcc acaatctact gttacgaaat caccgacgag gagccgtaca
     3061 tctgcccact gtcgcaccat cgttgcacct cgctgcacca gggcctcagt ttcctcacca
     3121 agaaccactg cgacgtggcc agcgtggagt tctcaaaggc ctatcggcta accaatacca
     3181 caattgaacc cctgagtttc acagtgcccc gcatcaagag cgagctgttc caagacgatc
     3241 tgttcccacc cacacgcatc acctggagcg ccacactgag ctccgaggat tggttcgcta
     3301 gcaatgataa ggcggcaccc aaagtcagcc tcaagcccga gggcatggaa actttatctt
     3361 ccatacagca agtgccagcg cagcccgtca agaagccaga tcatccccag ttcggtggcc
     3421 agaagtccga gtacgagatc aacaaacagc aggagatcca gaaatcggtt agcgcgcgca
     3481 tggaattcac caccaagctg gagcaggacg acatggaggg tgtggatgag aacgagtggc
     3541 aggagtagca gtatagccaa cgtctgcggc ggacatgaac catggaaatc agttcacaat
     3601 ttagcgttta acaaccaatg ggcgtaactt tttttttaac aatctaaaca tgacacgaca
     3661 tcatgacgac aacagcaagg tgctcgatat ctacaatcta cttgggagcg agcgtatata
     3721 gagaactcgt agctaagccg aaagttaaac taacacactc ccgtacacac accctcatcc
     3781 cttgtccctc gtcaacccag gattcagttc ctcctcagct ccttcgccaa taactgcagt
     3841 tgctcaataa ttgccaaatt aatcttcgta agccagtttt gttcgttttg ttaaacgttt
     3901 ttatatttgt gtatgtcctt ttttttattt tgtttaattg tgtgtgtttt aacttttgat
     3961 ttacccatac atatatgttc gtgttttttg tgtgctattt aagtagttag tccaaaatta
     4021 gtttagccta tttaggtgtt tacacttacg aataatttca ccggttctcc tatgtccttc
     4081 agtttatgtg gccatatagg aaaagtgagg agaaggactt agatgatact gcttttacat
     4141 atacgcaaaa tgtatttccc tctctgtttg tttcacgttt gcatgcgagt gagtgagaga
     4201 gatagagtgt gtgtgtgtgc ttgactatca cctttttttt cgcaatattt caccctcttt
     4261 ctacctatac catcatccat ccatctatcc gaaatgaaaa acccacccaa atcgaaccga
     4321 tgatgccgcc ccaaccccca ccattgtttc tagtctttcg catcgttcga tcccccaaat
     4381 gaagaccccc tccccttatc cttatgaccc aaccaacaac tagacaggaa acaaaaacat
     4441 atagactgta gccaaacgaa aaatttaata tattgctgag aactacaatc aagcgagaca
     4501 atttttatac tgaaaaatgc gtaaatcaaa caaactgcaa cagccgaatc aaaccgcaaa
     4561 gacatgcaaa caacacaatt ccaaaatgta taacgaaaag acttgatcag cggatgggtc
     4621 agttgcccag ctgccgccca tctccatcct tagaatccct cttccccaaa atgcccccta
     4681 ctaacgcaaa agaaaaggta cgagatgcca atgagaacgg atagggggaa agtaatgaaa
     4741 gttgccattg aaacgcgagc gagggaaggc aatagatcgt atctcgagta gcataaccca
     4801 taggcaataa cgttttgtac ttgcaataga atatacattt acacatatac atgatatatt
     4861 gatatatgat atattttgta taccaagcgt ataactataa atgctggcca agaacaagaa
     4921 ctcgaacttt tggctcgaac gactgaacca tagcgcgtgg caaatcgaaa ttcaaaaact
     4981 caaactcaaa tatttcaaaa cagaccaaca aaccaacaaa attctcgggt accgggcaat
     5041 attgtgctag acaaggttct attatacaga ttatatatac acataccata cgcatagtta
     5101 tataggcaaa ctgaagcaat tccagcaatt ccaaaatcaa agtccaaact gcatttaatt
     5161 aatacaaacg ccatggaacg actgacagac aagtattcgc taaacattct gatccaaatc
     5221 tgcccggccc gtcaaaaagt gttccacagc acgagtagaa ttgatctggg atcgattggg
     5281 atctcgggat cggggtagcg ggaacacagt tctataagca tataatccta cggcccagta
     5341 aacccaatcc aaattcaata ctaagcccgc agatattatg tcattctgta tttattagcc
     5401 atattcgatt acgattttcg aacgtctctt atttatattt atatatatct ataacaatac
     5461 caatatacga aaatacaact tcaagcgata tataatacga tgataagcga atgaaggatt
     5521 gattgattga ttgatgatga tgatgatgat atggtgatga ttcacagcgg aagtgcaagc
     5581 agaaagtagt gaggatggtt tatgaaagca aataagctga atcggaatca gaatctgatc
     5641 tgaatcagaa gcatacacat tatttataca atttatttta cagtacgagt atatccgata
     5701 atccccatcc gatactctag cactaagtta taattacaat aataataatg aaggcaaaaa
     5761 tatatttata tacataattc aataaaaaaa aacaaaaaga aattat
//
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