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Homo sapiens KCNQ1 downstream neighbor (KCNQ1DN), long non-coding RNA

NCBI Reference Sequence: NR_024627.1

FASTA Graphics 

LOCUS       NR_024627               1109 bp    RNA     linear   PRI 02-SEP-2020
DEFINITION  Homo sapiens KCNQ1 downstream neighbor (KCNQ1DN), long non-coding
            RNA.
ACCESSION   NR_024627 XR_039804 XR_039805 XR_039806
VERSION     NR_024627.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1109)
  AUTHORS   Koch CM and Wagner W.
  TITLE     Epigenetic-aging-signature to determine age in different tissues
  JOURNAL   Aging (Albany NY) 3 (10), 1018-1027 (2011)
   PUBMED   22067257
REFERENCE   2  (bases 1 to 1109)
  AUTHORS   Engemann S, Strodicke M, Paulsen M, Franck O, Reinhardt R, Lane N,
            Reik W and Walter J.
  TITLE     Sequence and functional comparison in the Beckwith-Wiedemann
            region: implications for a novel imprinting centre and extended
            imprinting
  JOURNAL   Hum. Mol. Genet. 9 (18), 2691-2706 (2000)
   PUBMED   11063728
REFERENCE   3  (bases 1 to 1109)
  AUTHORS   Xin Z, Soejima H, Higashimoto K, Yatsuki H, Zhu X, Satoh Y, Masaki
            Z, Kaneko Y, Jinno Y, Fukuzawa R, Hata Ji and Mukai T.
  TITLE     A novel imprinted gene, KCNQ1DN, within the WT2 critical region of
            human chromosome 11p15.5 and its reduced expression in Wilms'
            tumors
  JOURNAL   J. Biochem. 128 (5), 847-853 (2000)
   PUBMED   11056398
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AB039920.1.
            
            On or before Jan 2, 2009 this sequence version replaced
            XR_039804.1, XR_039806.1, XR_039805.1.
            
            Summary: Imprinting is a phenomenon in which epigenetic
            modifications lead to expression or suppression of alleles of some
            genes based on their parental origin. Wilms tumor-2 (WT2; MIM
            194071) is defined by maternal-specific loss of heterozygosity of a
            critical region on chromosome 11p15.5 that includes several
            imprinted genes. KCNQ1DN is an imprinted gene located within the
            WT2 critical region that is expressed from the maternal allele (Xin
            et al., 2000 [PubMed 11056398]).[supplied by OMIM, Mar 2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB039920.1, BC098159.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2145743
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1109              AB039920.1         1-1109
FEATURES             Location/Qualifiers
     source          1..1109
                     /organism="Homo sapiens"
                     /mol_type="transcribed RNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.4"
     gene            1..1109
                     /gene="KCNQ1DN"
                     /gene_synonym="BWRT; HSA404617"
                     /note="KCNQ1 downstream neighbor"
                     /db_xref="GeneID:55539"
                     /db_xref="HGNC:HGNC:13335"
                     /db_xref="MIM:610980"
     ncRNA           1..1109
                     /ncRNA_class="lncRNA"
                     /gene="KCNQ1DN"
                     /gene_synonym="BWRT; HSA404617"
                     /product="KCNQ1 downstream neighbor"
                     /db_xref="GeneID:55539"
                     /db_xref="HGNC:HGNC:13335"
                     /db_xref="MIM:610980"
     misc_feature    1..1109
                     /gene="KCNQ1DN"
                     /gene_synonym="BWRT; HSA404617"
                     /note="KCNQ1 downstream neighbor;
                     imprinted gene"
     exon            1..832
                     /gene="KCNQ1DN"
                     /gene_synonym="BWRT; HSA404617"
                     /inference="alignment:Splign:2.1.0"
     exon            833..1093
                     /gene="KCNQ1DN"
                     /gene_synonym="BWRT; HSA404617"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctgcccgca cgccccgacg ggagctgcgc ccagcctccc ctctggagtc ggcgctccag
       61 gctgctgccc ggccggtggc caaggcccca gcaccaccgt ccctcctgca gggcatccag
      121 cacctaccct tccactgggc ggctcctggt tctggtcccg gctggctcac tcaggctgcc
      181 tttggaccag attcttgaac ttttccacca aggatgttgc tgctgtttgt agcgtcggat
      241 cctggaaaat cgctgtgttg gggagcagca ggctctccct tgctccccca gggcctggga
      301 aaatcaaccc acctctgccc cccgacccca gggctgtaac ctggtgtctg gtagccccac
      361 tgtgataaac cgaagcccag cacagtttgg gactcgcccc gagttgactt atgcagcccc
      421 cagaacagag gctgaaaccc ggcgcatcct ggtgaagcca cacccagccg gcctggtccc
      481 aggccccggg cacggggtcc cctccactcc catctgcttc cctttcagag ccggggctga
      541 gtcggcaggg acgcaggctc agggccctgg attcccgctt tctggacact tgcgtgcatg
      601 cccagcacca gctcgccctt ctgagaaagc aatccctcct cagaggggag aagccgtggc
      661 tgtgatgggc aggaagtggt caggacccac tgccgagcac caactcccca tgccaccacc
      721 aggggtgcgc ctggactcct ggaaaggggt cgcgtcaggg tgcagcccat caaaggcttc
      781 ccaagaggca agaggcaagg agaagtgtcc tactttaaac ggccagcctc agtggtcggc
      841 cctgttcact ctgccacctc agagagagtg aacccagcag aggtgtgacg ggaggctggg
      901 gagagacccc agcaccttga gcacacagga gccaggagga gcccaacaga gcagcagggg
      961 ctggggtctt ctcctgaagc ctgactccat gggaccccaa agaagcagat ggaaaactga
     1021 aaaagaaaac ccctcaagtg agccactgga aagaaagcaa aacaagagaa aataaatgag
     1081 ttgtttgaca taaaaaaaaa aaaaaaaaa
//
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