Human mRNA fragment for p56(LSTRA) protein-tyrosine kinase

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ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion. [Cell. 2024]
ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion.
Deng S, Zhang Y, Wang H, Liang W, Xie L, Li N, Fang Y, Wang Y, Liu J, Chi H, et al. Cell. 2024 Apr 25; 187(9):2305-2323.e33. Epub 2024 Apr 12.
Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks. [Immunity. 2024]
Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks.
Jaeger-Ruckstuhl CA, Lo Y, Fulton E, Waltner OG, Shabaneh TB, Simon S, Muthuraman PV, Correnti CE, Newsom OJ, Engstrom IA, et al. Immunity. 2024 Feb 13; 57(2):287-302.e12.
Correction to: A Novel Biallelic LCK Variant Resulting in Profound T-Cell Immune Deficiency and Review of the Literature. [J Clin Immunol. 2024]
Correction to: A Novel Biallelic LCK Variant Resulting in Profound T-Cell Immune Deficiency and Review of the Literature.
Lanz AL, Erdem S, Ozcan A, Ceylaner G, Cansever M, Ceylaner S, Conca R, Magg T, Acuto O, Latour S, et al. J Clin Immunol. 2024 Jan 16; 44(1):41. Epub 2024 Jan 16.

RefSeq alternative splicing
See 13 reference mRNA sequence splice variants for the LCK gene.

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Nucleotide