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PREDICTED: Homo sapiens pleckstrin homology, MyTH4 and FERM domain containing H3 (PLEKHH3), transcript variant X2, mRNA

NCBI Reference Sequence: XM_017025114.2

FASTA Graphics 

LOCUS       XM_017025114            3018 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens pleckstrin homology, MyTH4 and FERM domain
            containing H3 (PLEKHH3), transcript variant X2, mRNA.
ACCESSION   XM_017025114
VERSION     XM_017025114.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017025114.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3018
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..3018
                     /gene="PLEKHH3"
                     /note="pleckstrin homology, MyTH4 and FERM domain
                     containing H3; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 15 ESTs, 53 long SRA
                     reads, and 100% coverage of the annotated genomic feature
                     by RNAseq alignments, including 4 samples with support for
                     all annotated introns"
                     /db_xref="GeneID:79990"
                     /db_xref="HGNC:HGNC:26105"
     CDS             166..2805
                     /gene="PLEKHH3"
                     /codon_start=1
                     /product="pleckstrin homology domain-containing family H
                     member 3 isoform X2"
                     /protein_id="XP_016880603.1"
                     /db_xref="GeneID:79990"
                     /db_xref="HGNC:HGNC:26105"
                     /translation="MCLWASRCRLGAIHLLGALRQGRRHAWPDLALPLPSPLGPRPIP
                     SPSASASAEECGEAGWAARTPGSPSAPSSQVRRPDARAPAAETWTRGRSHPRIGGGSV
                     EEGKMRRRGCLGAWQNELTSPVSKMGKLRPGDGKRLAQGSTGPLEVTLTQPVRSGPVS
                     NRLQSWEETWSLIPEKGLPEDDPDIVVKGWLYREPRGGGARPWLPPRRAWFVLTRDSL
                     DQFSSSGKGARRLGSLVLTSLCSVTGPERRRKETGLWSVTVSGRKHSVRLCSPRQAEA
                     ERWGVALREVIASKAPLETPTQLLLRDIQESCGDPEAVALIYLRNPILRHTSGALYAP
                     LLPLPYGVSAPGPGYAPLREEAVRLFLALQALEGARRPGPLMQGVLQTCRDLPALRDE
                     LFLQLAKQTSGPAGPPGLPATQDPAALRYWQLLTCMSCTFRPGGAVRGHLLGHLERTE
                     QALPDSELAEYARFIRKALGRTRGRELVPSLAEISALSQRQELLCTVHCPGAGACAVA
                     IDSHTTAGEVARELVGRLGLARSRNAFALYEQRGAQERALAGGTLVADVLTSLAAEEA
                     GLEDSPDSGWRLCLRLHGPLHPEGLSPDGHELPFLFEQAHALLLRGRPPPPDDTLRAL
                     AALRLQSLQRDFSPRVPLPRLDRLLPPPAPPREDPPRPTPRPPPSAALLAGALWSPGL
                     AKRRAERARRGGAGRTAGSIAREGGGGAGTAAAVLGGWKRLRGMGRAEAMAAYLALAA
                     QCPGFGAARYDVLELSTEPGRGAPQKLCLGLGAKAMSLSRPGETEPIHSVSYGHVAAC
                     QLMGPHTLALRVGESQLLLQSPQVEEIMQLVNAYLANPSPERPCSSSSPPCQDLPDTS
                     PPSQRPGLDEPQGQSGCLGQLQD"
ORIGIN      
        1 ggttcggagc ctcgtctcaa tcactctcgc tgtaaccggc cgtcacgctg atccgctcca
       61 gcctccagcc acacgctgcg cgcttggcga actagggatg agggagagtt ttttgcctgg
      121 gggccaaagc ccccgggagc tctcggagca gcagccctac tcgggatgtg cctgtgggcc
      181 tcccgctgca ggctgggcgc tatccacctg ctgggggccc tgaggcaggg gaggcgtcac
      241 gcgtggcccg acctggccct gcctctccct tccccgctgg gcccgcgtcc catcccgtct
      301 ccttccgcct ccgccagcgc cgaggaatgt ggcgaggccg gctgggcggc tcgaacgcct
      361 gggtccccct ccgctcccag ttcgcaagtg cggaggccag atgcgagagc tcccgctgcg
      421 gagacctgga cgagggggag aagtcatccc aggattgggg gaggcagtgt ggaagaaggg
      481 aaaatgagga ggagagggtg ccttggagcc tggcagaacg agctcacctc tcctgtttca
      541 aagatgggga aactaaggcc cggagacggg aagagacttg cccaaggttc cacaggtccc
      601 ctggaagtga cgctgactca gccagtgagg agcgggcctg tctccaacag gctgcagagc
      661 tgggaggaga cttggagcct catcccggag aaagggctgc cggaggacga cccggacatc
      721 gttgtgaaag gttggctgta ccgggagccc cgcggaggag gggcgcggcc ctggctgccc
      781 ccgcgccgag cctggtttgt gctcacgcgg gactccctgg atcagttcag cagcagcggg
      841 aaaggggcgc ggcgtctcgg gagcctcgtg ctcaccagcc tgtgctcggt gaccggccca
      901 gagcgcaggc gtaaggagac aggtctgtgg tcagtgactg tgtctggtcg gaaacacagt
      961 gtccgcctct gctccccacg ccaggcagag gctgagcgct ggggggtggc attgcgggaa
     1021 gtgatcgcct ccaaggcacc cctggagacc cccacccagc tactgctcag ggacatacag
     1081 gaaagttgcg gggacccaga ggccgttgcc ctcatttacc tgaggaaccc gattctgaga
     1141 cacactagtg gagccttgta tgccccactc ctgcccctgc cctatggagt cagcgcccca
     1201 ggtccgggct atgcacccct gcgcgaggag gcggtgcggc tgttcttggc gctgcaggcg
     1261 ctggaggggg cgcggcgccc cgggcccttg atgcagggtg tgctccaaac ctgccgggac
     1321 ttgcccgcgc tccgggatga actcttcctg cagctggcta agcagacctc gggccctgca
     1381 ggtccccccg ggctcccggc tacccaagac cctgcggccc tgcggtactg gcaactcctc
     1441 acctgcatga gctgcacctt ccgacctggg ggagctgtgc gggggcacct cctggggcac
     1501 ttggagagga ccgagcaggc actcccggac tcggaactgg cggaatatgc gcgcttcatc
     1561 cggaaagcgc tgggccggac gcgcggcaga gagctggtgc cctcgctggc ggagatttcc
     1621 gcgttgagcc aacggcagga gctgctgtgt accgtgcact gtccgggggc tggtgcctgt
     1681 gctgtggcca tcgactccca caccacggcg ggggaggtgg ctcgagagct ggtggggcgg
     1741 ctgggcttgg cccggagccg caacgcattc gcgctgtacg agcagcgagg ggcccaggag
     1801 cgagccctgg ctggggggac cctcgtggcc gacgtgctca ccagcttggc cgcggaggaa
     1861 gctgggttgg aggactcgcc cgactccggg tggagactat gtctgcgtct tcacggacct
     1921 ctgcaccctg aggggctgtc cccagacggt cacgaactgc ctttcctctt tgagcaggct
     1981 cacgctctgc tgctgcgggg ccggccgccc ccacccgacg acacgctgcg cgccctggcg
     2041 gcgctgcgcc tgcagagcct gcagcgggac ttctctccgc gggtgcccct gccccgcctg
     2101 gaccgcctgc tcccgccccc ggccccgccg cgcgaagacc cgccccgccc gacccccagg
     2161 ccgccccctt ccgctgccct gctggccggg gcgctctgga gcccgggcct ggccaagagg
     2221 cgggcggagc gggcccggcg cggcggggcc ggccgcactg cgggaagcat tgcccgcgag
     2281 ggaggaggcg gcgccggcac ggcagctgcc gtgctgggcg gctggaagcg gctacggggc
     2341 atgggccgag ctgaggccat ggccgcctac ctggccctgg cggcgcagtg tccggggttc
     2401 ggcgctgctc ggtatgacgt tctggagctg agcacggagc ctggtcgggg tgctccacag
     2461 aagctgtgcc tgggcttggg agccaaggcc atgtccctct cccggccagg ggagacggag
     2521 cccatccaca gtgtcagcta tggccatgtg gccgcctgcc agctaatggg cccccacacc
     2581 ctggccttga gggtgggaga gagccagctc ctcctgcaga gcccccaggt ggaagagatc
     2641 atgcagctgg tgaatgccta cttggccaac ccctcccccg agaggccctg cagcagctct
     2701 tctcctccat gccaagacct gccagacacc tcccctccca gccagcgccc gggcctggac
     2761 gagccccagg gacagtctgg ctgcttgggg cagctgcagg actgagcctg ccaagaggtc
     2821 acgacttccc tcctgcctgc agcctgggcc aggactgctc tgagatttga gggaaacatg
     2881 gacccttttg gccctgcagg gacagggcac atcccacacc caagggctac aatgggtgtg
     2941 ggtaattttc tagtttgttt cttaatttat ttgtagaaga gaagcaaaaa aaaaaaaaaa
     3001 gtttcttatt tacacaaa
//
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Reference sequence information

  • RefSeq alternative splicing
    See 18 reference mRNA sequence splice variants for the PLEKHH3 gene.
  • RefSeq protein product
    See the reference protein sequence for pleckstrin homology domain-containing family H member 3 isoform X2 (XP_016880603.1).

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