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PREDICTED: Homo sapiens synaptic Ras GTPase activating protein 1 (SYNGAP1), transcript variant X4, mRNA

NCBI Reference Sequence: XM_047419454.1

FASTA Graphics 

LOCUS       XM_047419454            5970 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens synaptic Ras GTPase activating protein 1
            (SYNGAP1), transcript variant X4, mRNA.
ACCESSION   XM_047419454
VERSION     XM_047419454.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000006.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5970
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
     gene            1..5970
                     /gene="SYNGAP1"
                     /gene_synonym="MRD5; RASA1; RASA5; SYNGAP"
                     /note="synaptic Ras GTPase activating protein 1; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 2 mRNAs, 30 ESTs, 91 long SRA reads, and 98% coverage
                     of the annotated genomic feature by RNAseq alignments,
                     including 51 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:8831"
                     /db_xref="HGNC:HGNC:11497"
                     /db_xref="MIM:603384"
     CDS             201..4187
                     /gene="SYNGAP1"
                     /gene_synonym="MRD5; RASA1; RASA5; SYNGAP"
                     /codon_start=1
                     /product="ras/Rap GTPase-activating protein SynGAP isoform
                     X4"
                     /protein_id="XP_047275410.1"
                     /db_xref="GeneID:8831"
                     /db_xref="HGNC:HGNC:11497"
                     /db_xref="MIM:603384"
                     /translation="MSRSRASIHRGSIPAMSYAPFRDVRGPSMHRTQYVHSPYDRPGW
                     NPRFCIISGNQLLMLDEDEIHPLLIRDRRSESSRNKLLRRTVSVPVEGRPHGEHEYHL
                     GRSRRKSVPGGKQYSMEGAPAAPFRPSQGFLSRRLKSSIKRTKSQPKLDRTSSFRQIL
                     PRFRSADHDRARLMQSFKESHSHESLLSPSSAAEALELNLDEDSIIKPVHSSILGQEF
                     CFEVTTSSGTKCFACRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARELPP
                     KKRYYCELCLDDMLYARTTSKPRSASGDTVFWGEHFEFNNLPAVRALRLHLYRDSDKK
                     RKKDKAGYVGLVTVPVATLAGRHFTEQWYPVTLPTGSGGSGGMGSGGGGGSGGGSGGK
                     GKGGCPAVRLKARYQTMSILPMELYKEFAEYVTNHYRMLCAVLEPALNVKGKEEVASA
                     LVHILQSTGKAKDFLSDMAMSEVDRFMEREHLIFRENTLATKAIEEYMRLIGQKYLKD
                     AIGEFIRALYESEENCEVDPIKCTASSLAEHQANLRMCCELALCKVVNSHCVFPRELK
                     EVFASWRLRCAERGREDIADRLISASLFLRFLCPAIMSPSLFGLMQEYPDEQTSRTLT
                     LIAKVIQNLANFSKFTSKEDFLGFMNEFLELEWGSMQQFLYEISNLDTLTNSSSFEGY
                     IDLGRELSTLHALLWEVLPQLSKEALLKLGPLPRLLNDISTALRNPNIQRQPSRQSER
                     PRPQPVVLRGPSAEMQGYMMRDLNSSMDMARLPSPTKEKPPPPPPGGGKDLFYVSRPP
                     LARSSPAYCTSSSDITEPEQKMLSVNKSVSMLDLQGDGPGGRLNSSSVSNLAAVGDLL
                     HSSQASLTAALGLRPAPAGRLSQGSGSSITAAGMRLSQMGVTTDGVPAQQLRIPLSFQ
                     NPLFHMAADGPGPPGGHGGGGGHGPPSSHHHHHHHHHHRGGEPPGDTFAPFHGYSKSE
                     DLSSGVPKPPAASILHSHSYSDEFGPSGTDFTRRQLSLQDNLQHMLSPPQITIGPQRP
                     APSGPGGGSGGGSGGGGGGQPPPLQRGKSQQLTVSAAQKPRPSSGNLLQSPEPSYGPA
                     RPRQQSLSKEGSIGGSGGSGGGGGGGLKPSITKQHSQTPSTLNPTMPASERTVAWVSN
                     MPHLSADIESAHIEREEYKLKEYSKSMDESRLDREYEEEIHSLKERLHMSNRKLEEYE
                     RRLLSQEEQTSKILMQYQARLEQSEKRLRQQQAEKDSQIKSIIGRLMLVEEELRRDHP
                     AMAEPLPEPKKRLLDAQVERQLPPLGPTNPRVTLAPPWNGLAPPAPPPPPRLQITENG
                     EFRNTADH"
ORIGIN      
        1 ctctctctcg gctgccgctg ctgccgttgg ctcttattct cctcctcctc ctcctctctc
       61 ctcctctctg cttctctctg ctcctctctc ctcctctctc ctcctcctcc tcctccacct
      121 cctcctcctt ctccccctct ttctccccct ctttctctct tctttctccc ccgtcccccc
      181 gccccctccc cccaggcctg atgagcaggt ctcgagcctc catccatcgg gggagcatcc
      241 ccgcgatgtc ctatgccccc ttcagagatg tacggggacc ctctatgcac cgaacccaat
      301 acgttcattc cccgtatgat cgtcctggtt ggaaccctcg gttctgcatc atctcgggga
      361 accagctgct catgctggat gaggatgaga tacaccccct actgatccgg gaccggagga
      421 gcgagtccag tcgcaacaaa ctgctgagac gcacagtctc cgtgccggtg gaggggcggc
      481 cccacggcga gcatgaatac cacttgggtc gctcgaggag gaagagtgtc ccagggggga
      541 agcagtacag catggagggt gcccctgctg cgcccttccg gccctcgcaa ggcttcctga
      601 gccgacggct aaaaagctcc atcaaacgaa cgaagtcaca acccaaactt gaccggacca
      661 gcagctttcg ccagatcctg cctcgcttcc gaagtgctga ccatgaccgg gcccggctga
      721 tgcaaagctt taaggagtca cactctcatg agtccttgct gagtcctagc agtgcagctg
      781 aggcattgga gctcaacttg gatgaagatt ccattatcaa gccagtgcac agctccatcc
      841 tgggccagga gttctgtttt gaggtaacaa cttcatcagg aacaaaatgc tttgcctgtc
      901 ggtctgcggc cgaaagagac aaatggattg agaatctgca gcgggcagta aagcccaaca
      961 aggacaacag ccgccgggta gacaatgtgc taaagctgtg gatcatagag gcccgggagc
     1021 tgccccccaa gaagcggtac tactgtgagc tctgcctgga tgacatgctg tatgcacgca
     1081 ccacctccaa gccccgctct gcctctgggg acaccgtctt ctggggcgag cacttcgagt
     1141 ttaacaacct gccggctgtc cgtgccctgc ggctgcatct gtaccgtgac tcagacaaaa
     1201 agcgcaagaa ggacaaggca ggctatgtcg gcctggtgac tgtgccagtg gccaccctgg
     1261 ctgggcgcca cttcacagag cagtggtacc ctgtaaccct gccaacaggc agtgggggat
     1321 ctgggggcat gggttcggga gggggagggg gctcgggggg tggctcaggg ggcaagggca
     1381 aaggaggttg cccggctgtg cggctgaaag cacgttacca gacaatgagc atcttgccca
     1441 tggagctata taaagagttt gcagagtatg tcaccaacca ttatcggatg ctgtgtgcag
     1501 tcttggagcc cgccctgaat gtcaaaggca aggaggaggt tgccagtgca ctagttcaca
     1561 tcctgcagag tacaggcaag gccaaggact tcctttcaga catggccatg tctgaggtag
     1621 accggttcat ggaacgggag cacctcatat tccgcgagaa cacgcttgcc actaaagcca
     1681 tagaagagta tatgagactg attggtcaga aatacctcaa ggatgccatt ggagaattca
     1741 tccgtgctct gtatgaatct gaggaaaact gcgaggtaga ccctatcaag tgcacagcat
     1801 ccagtttggc agagcaccag gccaacctgc gaatgtgctg tgagttggcc ctgtgcaagg
     1861 tggtcaactc ccactgcgtg ttcccgaggg agctgaagga ggtgtttgct tcgtggcggc
     1921 tgcgctgcgc agagcgaggc cgggaggaca tcgcagacag gcttatcagc gcctcactct
     1981 tcctgcgctt cctctgccca gcgattatgt cgcccagtct ctttgggctt atgcaggagt
     2041 acccagatga gcagacctca cgaaccctca ccctcattgc caaggtcatc cagaacctgg
     2101 ccaacttttc caagtttacc tcaaaggagg actttctggg cttcatgaat gagtttctgg
     2161 agctggaatg gggttccatg cagcagtttt tgtatgagat ctccaatctg gacacgctaa
     2221 ccaacagcag tagctttgag ggttacatcg acttgggccg agagctctcc acactgcatg
     2281 ccctactctg ggaggtgctg ccccagctca gcaaggaagc cctcctgaag ctgggtccac
     2341 tgccccggct cctcaacgac atcagcacag ctctgaggaa ccccaacatc caaaggcagc
     2401 caagccgcca gagtgagcgg ccccggcctc agcctgtggt actgcggggg ccatcggctg
     2461 agatgcaggg ctacatgatg cgggacctca acagctctat ggacatggct cgcctcccct
     2521 ccccaaccaa ggaaaagcca cccccaccac cgcctggtgg tggtaaagac ctgttctatg
     2581 taagccgtcc acccctggcc cgttcctcac cagcatactg cacgagcagc tcggacatca
     2641 cagagccaga gcagaagatg ctgagtgtca acaagagtgt gtccatgctg gacttacagg
     2701 gtgatgggcc tggtggccgc ctcaacagca gcagtgtttc gaacctggcg gccgtagggg
     2761 acctgctgca ctcaagccag gcctcgctga cagcagcctt ggggctacgg cctgcgcctg
     2821 ccggacgcct ctcccagggg agtggctcat ccatcacggc ggctggcatg cgcctcagcc
     2881 agatgggtgt caccacagac ggtgtccctg cccagcaact gcgaatcccc ctctccttcc
     2941 agaaccctct cttccacatg gctgctgatg ggccaggtcc cccaggcggc catggagggg
     3001 gcggtggcca tggcccacct tcctcccatc accaccacca ccaccatcac caccaccgag
     3061 gtggagagcc ccctggggac acctttgccc cattccatgg ctatagcaag agtgaggacc
     3121 tctcttccgg ggtccccaag ccccctgctg cctccatcct tcatagccac agctacagtg
     3181 atgagtttgg accctctggc actgacttca cccgtcggca gctttcactc caggacaacc
     3241 tgcagcacat gctgtcccct ccccagatca ccattggtcc ccagaggcca gccccctcag
     3301 ggcctggagg tgggagcggt gggggcagcg gtgggggtgg cgggggccag ccgcctccat
     3361 tgcagagggg caagtctcag cagttgacag tcagcgcagc ccagaaaccc cggccatcca
     3421 gcgggaatct attgcagtcc ccagagccaa gttatggccc cgcccgtcca cggcaacaga
     3481 gcctcagcaa ggagggcagc attgggggca gcgggggcag cggtggcgga gggggtgggg
     3541 ggctgaagcc ctccatcacc aagcagcatt ctcagacacc atccacattg aaccccacaa
     3601 tgccagcctc tgagcggaca gtggcctggg tctccaacat gcctcacctg tcggctgaca
     3661 tcgagagtgc ccacatcgag cgggaagagt acaagctcaa ggagtactca aaatcgatgg
     3721 atgagagccg gctggatagg gagtacgagg aggagattca ctcactgaaa gagcggctgc
     3781 acatgtccaa ccggaagctg gaagagtatg agcggaggct gctgtcccag gaagaacaaa
     3841 ccagcaaaat cctgatgcag tatcaggccc gactggagca gagtgagaag aggctaaggc
     3901 agcagcaggc agagaaggat tcccagatca agagcatcat tggcaggctg atgctggtgg
     3961 aggaggagct gcgccgggac caccccgcca tggctgagcc gctgccagaa cccaagaaga
     4021 ggctgctcga cgctcaggtg gagaggcagc ttcccccctt gggtccaaca aacccgcgtg
     4081 tgacgctggc cccaccgtgg aatggcctgg cccccccagc cccaccaccc ccaccccggc
     4141 tgcagattac ggagaacggc gagttccgaa acaccgcaga ccactagccc acccagcatc
     4201 agagaccttc tcttcctttc ctgtgcaccc caccctgtaa cagcaccaac caccaggatt
     4261 ggacatcacc gaggaacagc gggattgcct ccccgaatgc ctccctggga ggcacactga
     4321 ttgcccaccc ccaccactgc accatttcca ggagggagag tggggaccct cagccgcccc
     4381 cttttccttc ccattggggt gctgccctct ctttgacccc cagggaccct tgccccagga
     4441 caccgcctac cccgtacaga ccccttcact ccggggtgct atccccatcc tctgcctcat
     4501 cgttcccctg agcactgggg gacagaccct cacccccacc ctgggggtgt ggcacctcca
     4561 aactttcaac ttcagggtga tttttttagc agtaaccaga gctgacaatc taactcccct
     4621 ccaccgcccc attttggcct cccctgcccc ccttgttatg gggaggggac cccgggtgag
     4681 ggggccctat taccccttga tttctcagga gcgtctgggg gggctcagca cgcacaaact
     4741 ccttctcctt ctaccactct taaatttact ccctccccac ccagaaccca gatggggtgg
     4801 agggggccac cggggcaggg agggggcggc aaggggggaa tgggagttgt ctccccttct
     4861 ccccacacct gatctgctct cggctggtcc cagagcgggg tgagggggct tatgcccccc
     4921 cctcccccag tgtgttgggt ggggtggaat tgaggttagg gtgaggggtc agggtttagg
     4981 agggtgtgta tgttgggagg acaggctagt tgatctgtcc tactctgaca cacagtcccc
     5041 tctgcccctt ccttctctct tcttggtctc tactcccagg gggagggggg aacttactct
     5101 aggaaaagcc atgtctctct cccccagggt ggggggacct gtgttggagg aggggtgttg
     5161 gggggccccc ttccatgact ctgtcccctg ggggaggtag gacagggctg ggcttccctc
     5221 tcatcctccc cctcccaatc tccttccacc tccctccctc ccgccagctc cacgattttt
     5281 cggtgtttct ctgtacatag ttttctggcg ggatagggga ggtaggatgg atggggtttg
     5341 gggtgggtag gccatgggag gggagaagcc cctccttggc accccctctt ccctgactgc
     5401 tgtcccctac ccagccttgc ccccttcatc cttttgcgtt tggtattgag actctcctag
     5461 actctactcc tctttctttt gtatggacag ttccccttca gtcccatccc cctacacata
     5521 cacccagccg gggccaaatt tatacttata taaaagttgt aaatatgtga aattttatcc
     5581 ctgtgccctt tccccacctc aggccctacc cctggaccct ccccaacctt ccttctctct
     5641 tctttggctg ttgtaattat ctggggtttg tactgtacat atccggggtg tgtgtgtgtg
     5701 ggctgggggc aacccttctg tacagagctt cctggccccc tccccccccg cccctctgct
     5761 tccctcccca cccaccacct caagggtagg gagttgctct tcctacctgt tttattttgt
     5821 tttctcgttc tccctcccca ccccactccc agccttatct atcccccctc actgtcccct
     5881 tttctccact cccagcccca tttccttttt ttctggagtg tgtggtgaaa cagaaaaaaa
     5941 catgtttaat aaacggagat tgttctttta
//
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