Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Download features.
Download gene features.
NCBI Reference Sequence: XM_047419454.1
FASTA Graphics
LOCUS XM_047419454 5970 bp mRNA linear PRI 25-AUG-2024 DEFINITION PREDICTED: Homo sapiens synaptic Ras GTPase activating protein 1 (SYNGAP1), transcript variant X4, mRNA. ACCESSION XM_047419454 VERSION XM_047419454.1 DBLINK BioProject: PRJNA168 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Updated annotation Annotation Name :: GCF_000001405.40-RS_2024_08 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; RefSeqFE; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 08/23/2024 ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..5970 /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /chromosome="6" gene 1..5970 /gene="SYNGAP1" /gene_synonym="MRD5; RASA1; RASA5; SYNGAP" /note="synaptic Ras GTPase activating protein 1; Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 2 mRNAs, 30 ESTs, 91 long SRA reads, and 98% coverage of the annotated genomic feature by RNAseq alignments, including 51 samples with support for all annotated introns" /db_xref="GeneID:8831" /db_xref="HGNC:HGNC:11497" /db_xref="MIM:603384" CDS 201..4187 /gene="SYNGAP1" /gene_synonym="MRD5; RASA1; RASA5; SYNGAP" /codon_start=1 /product="ras/Rap GTPase-activating protein SynGAP isoform X4" /protein_id="XP_047275410.1" /db_xref="GeneID:8831" /db_xref="HGNC:HGNC:11497" /db_xref="MIM:603384" /translation="MSRSRASIHRGSIPAMSYAPFRDVRGPSMHRTQYVHSPYDRPGW NPRFCIISGNQLLMLDEDEIHPLLIRDRRSESSRNKLLRRTVSVPVEGRPHGEHEYHL GRSRRKSVPGGKQYSMEGAPAAPFRPSQGFLSRRLKSSIKRTKSQPKLDRTSSFRQIL PRFRSADHDRARLMQSFKESHSHESLLSPSSAAEALELNLDEDSIIKPVHSSILGQEF CFEVTTSSGTKCFACRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARELPP KKRYYCELCLDDMLYARTTSKPRSASGDTVFWGEHFEFNNLPAVRALRLHLYRDSDKK RKKDKAGYVGLVTVPVATLAGRHFTEQWYPVTLPTGSGGSGGMGSGGGGGSGGGSGGK GKGGCPAVRLKARYQTMSILPMELYKEFAEYVTNHYRMLCAVLEPALNVKGKEEVASA LVHILQSTGKAKDFLSDMAMSEVDRFMEREHLIFRENTLATKAIEEYMRLIGQKYLKD AIGEFIRALYESEENCEVDPIKCTASSLAEHQANLRMCCELALCKVVNSHCVFPRELK EVFASWRLRCAERGREDIADRLISASLFLRFLCPAIMSPSLFGLMQEYPDEQTSRTLT LIAKVIQNLANFSKFTSKEDFLGFMNEFLELEWGSMQQFLYEISNLDTLTNSSSFEGY IDLGRELSTLHALLWEVLPQLSKEALLKLGPLPRLLNDISTALRNPNIQRQPSRQSER PRPQPVVLRGPSAEMQGYMMRDLNSSMDMARLPSPTKEKPPPPPPGGGKDLFYVSRPP LARSSPAYCTSSSDITEPEQKMLSVNKSVSMLDLQGDGPGGRLNSSSVSNLAAVGDLL HSSQASLTAALGLRPAPAGRLSQGSGSSITAAGMRLSQMGVTTDGVPAQQLRIPLSFQ NPLFHMAADGPGPPGGHGGGGGHGPPSSHHHHHHHHHHRGGEPPGDTFAPFHGYSKSE DLSSGVPKPPAASILHSHSYSDEFGPSGTDFTRRQLSLQDNLQHMLSPPQITIGPQRP APSGPGGGSGGGSGGGGGGQPPPLQRGKSQQLTVSAAQKPRPSSGNLLQSPEPSYGPA RPRQQSLSKEGSIGGSGGSGGGGGGGLKPSITKQHSQTPSTLNPTMPASERTVAWVSN MPHLSADIESAHIEREEYKLKEYSKSMDESRLDREYEEEIHSLKERLHMSNRKLEEYE RRLLSQEEQTSKILMQYQARLEQSEKRLRQQQAEKDSQIKSIIGRLMLVEEELRRDHP AMAEPLPEPKKRLLDAQVERQLPPLGPTNPRVTLAPPWNGLAPPAPPPPPRLQITENG EFRNTADH" ORIGIN 1 ctctctctcg gctgccgctg ctgccgttgg ctcttattct cctcctcctc ctcctctctc 61 ctcctctctg cttctctctg ctcctctctc ctcctctctc ctcctcctcc tcctccacct 121 cctcctcctt ctccccctct ttctccccct ctttctctct tctttctccc ccgtcccccc 181 gccccctccc cccaggcctg atgagcaggt ctcgagcctc catccatcgg gggagcatcc 241 ccgcgatgtc ctatgccccc ttcagagatg tacggggacc ctctatgcac cgaacccaat 301 acgttcattc cccgtatgat cgtcctggtt ggaaccctcg gttctgcatc atctcgggga 361 accagctgct catgctggat gaggatgaga tacaccccct actgatccgg gaccggagga 421 gcgagtccag tcgcaacaaa ctgctgagac gcacagtctc cgtgccggtg gaggggcggc 481 cccacggcga gcatgaatac cacttgggtc gctcgaggag gaagagtgtc ccagggggga 541 agcagtacag catggagggt gcccctgctg cgcccttccg gccctcgcaa ggcttcctga 601 gccgacggct aaaaagctcc atcaaacgaa cgaagtcaca acccaaactt gaccggacca 661 gcagctttcg ccagatcctg cctcgcttcc gaagtgctga ccatgaccgg gcccggctga 721 tgcaaagctt taaggagtca cactctcatg agtccttgct gagtcctagc agtgcagctg 781 aggcattgga gctcaacttg gatgaagatt ccattatcaa gccagtgcac agctccatcc 841 tgggccagga gttctgtttt gaggtaacaa cttcatcagg aacaaaatgc tttgcctgtc 901 ggtctgcggc cgaaagagac aaatggattg agaatctgca gcgggcagta aagcccaaca 961 aggacaacag ccgccgggta gacaatgtgc taaagctgtg gatcatagag gcccgggagc 1021 tgccccccaa gaagcggtac tactgtgagc tctgcctgga tgacatgctg tatgcacgca 1081 ccacctccaa gccccgctct gcctctgggg acaccgtctt ctggggcgag cacttcgagt 1141 ttaacaacct gccggctgtc cgtgccctgc ggctgcatct gtaccgtgac tcagacaaaa 1201 agcgcaagaa ggacaaggca ggctatgtcg gcctggtgac tgtgccagtg gccaccctgg 1261 ctgggcgcca cttcacagag cagtggtacc ctgtaaccct gccaacaggc agtgggggat 1321 ctgggggcat gggttcggga gggggagggg gctcgggggg tggctcaggg ggcaagggca 1381 aaggaggttg cccggctgtg cggctgaaag cacgttacca gacaatgagc atcttgccca 1441 tggagctata taaagagttt gcagagtatg tcaccaacca ttatcggatg ctgtgtgcag 1501 tcttggagcc cgccctgaat gtcaaaggca aggaggaggt tgccagtgca ctagttcaca 1561 tcctgcagag tacaggcaag gccaaggact tcctttcaga catggccatg tctgaggtag 1621 accggttcat ggaacgggag cacctcatat tccgcgagaa cacgcttgcc actaaagcca 1681 tagaagagta tatgagactg attggtcaga aatacctcaa ggatgccatt ggagaattca 1741 tccgtgctct gtatgaatct gaggaaaact gcgaggtaga ccctatcaag tgcacagcat 1801 ccagtttggc agagcaccag gccaacctgc gaatgtgctg tgagttggcc ctgtgcaagg 1861 tggtcaactc ccactgcgtg ttcccgaggg agctgaagga ggtgtttgct tcgtggcggc 1921 tgcgctgcgc agagcgaggc cgggaggaca tcgcagacag gcttatcagc gcctcactct 1981 tcctgcgctt cctctgccca gcgattatgt cgcccagtct ctttgggctt atgcaggagt 2041 acccagatga gcagacctca cgaaccctca ccctcattgc caaggtcatc cagaacctgg 2101 ccaacttttc caagtttacc tcaaaggagg actttctggg cttcatgaat gagtttctgg 2161 agctggaatg gggttccatg cagcagtttt tgtatgagat ctccaatctg gacacgctaa 2221 ccaacagcag tagctttgag ggttacatcg acttgggccg agagctctcc acactgcatg 2281 ccctactctg ggaggtgctg ccccagctca gcaaggaagc cctcctgaag ctgggtccac 2341 tgccccggct cctcaacgac atcagcacag ctctgaggaa ccccaacatc caaaggcagc 2401 caagccgcca gagtgagcgg ccccggcctc agcctgtggt actgcggggg ccatcggctg 2461 agatgcaggg ctacatgatg cgggacctca acagctctat ggacatggct cgcctcccct 2521 ccccaaccaa ggaaaagcca cccccaccac cgcctggtgg tggtaaagac ctgttctatg 2581 taagccgtcc acccctggcc cgttcctcac cagcatactg cacgagcagc tcggacatca 2641 cagagccaga gcagaagatg ctgagtgtca acaagagtgt gtccatgctg gacttacagg 2701 gtgatgggcc tggtggccgc ctcaacagca gcagtgtttc gaacctggcg gccgtagggg 2761 acctgctgca ctcaagccag gcctcgctga cagcagcctt ggggctacgg cctgcgcctg 2821 ccggacgcct ctcccagggg agtggctcat ccatcacggc ggctggcatg cgcctcagcc 2881 agatgggtgt caccacagac ggtgtccctg cccagcaact gcgaatcccc ctctccttcc 2941 agaaccctct cttccacatg gctgctgatg ggccaggtcc cccaggcggc catggagggg 3001 gcggtggcca tggcccacct tcctcccatc accaccacca ccaccatcac caccaccgag 3061 gtggagagcc ccctggggac acctttgccc cattccatgg ctatagcaag agtgaggacc 3121 tctcttccgg ggtccccaag ccccctgctg cctccatcct tcatagccac agctacagtg 3181 atgagtttgg accctctggc actgacttca cccgtcggca gctttcactc caggacaacc 3241 tgcagcacat gctgtcccct ccccagatca ccattggtcc ccagaggcca gccccctcag 3301 ggcctggagg tgggagcggt gggggcagcg gtgggggtgg cgggggccag ccgcctccat 3361 tgcagagggg caagtctcag cagttgacag tcagcgcagc ccagaaaccc cggccatcca 3421 gcgggaatct attgcagtcc ccagagccaa gttatggccc cgcccgtcca cggcaacaga 3481 gcctcagcaa ggagggcagc attgggggca gcgggggcag cggtggcgga gggggtgggg 3541 ggctgaagcc ctccatcacc aagcagcatt ctcagacacc atccacattg aaccccacaa 3601 tgccagcctc tgagcggaca gtggcctggg tctccaacat gcctcacctg tcggctgaca 3661 tcgagagtgc ccacatcgag cgggaagagt acaagctcaa ggagtactca aaatcgatgg 3721 atgagagccg gctggatagg gagtacgagg aggagattca ctcactgaaa gagcggctgc 3781 acatgtccaa ccggaagctg gaagagtatg agcggaggct gctgtcccag gaagaacaaa 3841 ccagcaaaat cctgatgcag tatcaggccc gactggagca gagtgagaag aggctaaggc 3901 agcagcaggc agagaaggat tcccagatca agagcatcat tggcaggctg atgctggtgg 3961 aggaggagct gcgccgggac caccccgcca tggctgagcc gctgccagaa cccaagaaga 4021 ggctgctcga cgctcaggtg gagaggcagc ttcccccctt gggtccaaca aacccgcgtg 4081 tgacgctggc cccaccgtgg aatggcctgg cccccccagc cccaccaccc ccaccccggc 4141 tgcagattac ggagaacggc gagttccgaa acaccgcaga ccactagccc acccagcatc 4201 agagaccttc tcttcctttc ctgtgcaccc caccctgtaa cagcaccaac caccaggatt 4261 ggacatcacc gaggaacagc gggattgcct ccccgaatgc ctccctggga ggcacactga 4321 ttgcccaccc ccaccactgc accatttcca ggagggagag tggggaccct cagccgcccc 4381 cttttccttc ccattggggt gctgccctct ctttgacccc cagggaccct tgccccagga 4441 caccgcctac cccgtacaga ccccttcact ccggggtgct atccccatcc tctgcctcat 4501 cgttcccctg agcactgggg gacagaccct cacccccacc ctgggggtgt ggcacctcca 4561 aactttcaac ttcagggtga tttttttagc agtaaccaga gctgacaatc taactcccct 4621 ccaccgcccc attttggcct cccctgcccc ccttgttatg gggaggggac cccgggtgag 4681 ggggccctat taccccttga tttctcagga gcgtctgggg gggctcagca cgcacaaact 4741 ccttctcctt ctaccactct taaatttact ccctccccac ccagaaccca gatggggtgg 4801 agggggccac cggggcaggg agggggcggc aaggggggaa tgggagttgt ctccccttct 4861 ccccacacct gatctgctct cggctggtcc cagagcgggg tgagggggct tatgcccccc 4921 cctcccccag tgtgttgggt ggggtggaat tgaggttagg gtgaggggtc agggtttagg 4981 agggtgtgta tgttgggagg acaggctagt tgatctgtcc tactctgaca cacagtcccc 5041 tctgcccctt ccttctctct tcttggtctc tactcccagg gggagggggg aacttactct 5101 aggaaaagcc atgtctctct cccccagggt ggggggacct gtgttggagg aggggtgttg 5161 gggggccccc ttccatgact ctgtcccctg ggggaggtag gacagggctg ggcttccctc 5221 tcatcctccc cctcccaatc tccttccacc tccctccctc ccgccagctc cacgattttt 5281 cggtgtttct ctgtacatag ttttctggcg ggatagggga ggtaggatgg atggggtttg 5341 gggtgggtag gccatgggag gggagaagcc cctccttggc accccctctt ccctgactgc 5401 tgtcccctac ccagccttgc ccccttcatc cttttgcgtt tggtattgag actctcctag 5461 actctactcc tctttctttt gtatggacag ttccccttca gtcccatccc cctacacata 5521 cacccagccg gggccaaatt tatacttata taaaagttgt aaatatgtga aattttatcc 5581 ctgtgccctt tccccacctc aggccctacc cctggaccct ccccaacctt ccttctctct 5641 tctttggctg ttgtaattat ctggggtttg tactgtacat atccggggtg tgtgtgtgtg 5701 ggctgggggc aacccttctg tacagagctt cctggccccc tccccccccg cccctctgct 5761 tccctcccca cccaccacct caagggtagg gagttgctct tcctacctgt tttattttgt 5821 tttctcgttc tccctcccca ccccactccc agccttatct atcccccctc actgtcccct 5881 tttctccact cccagcccca tttccttttt ttctggagtg tgtggtgaaa cagaaaaaaa 5941 catgtttaat aaacggagat tgttctttta //
Whole sequence Selected region from: to:
All features Gene, RNA, and CDS features only
SNP
Show sequence Show reverse complement Show gap features
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on