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PREDICTED: Homo sapiens methionyl-tRNA synthetase 1 (MARS1), transcript variant X2, mRNA

NCBI Reference Sequence: XM_047428852.1

FASTA Graphics 

LOCUS       XM_047428852            1728 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens methionyl-tRNA synthetase 1 (MARS1),
            transcript variant X2, mRNA.
ACCESSION   XM_047428852
VERSION     XM_047428852.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000012.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1728
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
     gene            1..1728
                     /gene="MARS1"
                     /gene_synonym="CMT2U; ILFS2; ILLD; MARS; METRS; MRS;
                     MTRNS; SPG70; TTD9"
                     /note="methionyl-tRNA synthetase 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 596
                     ESTs, 272 long SRA reads, 1 Protein, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 129 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:4141"
                     /db_xref="HGNC:HGNC:6898"
                     /db_xref="MIM:156560"
     misc_feature    1
                     /gene="MARS1"
                     /gene_synonym="CMT2U; ILFS2; ILLD; MARS; METRS; MRS;
                     MTRNS; SPG70; TTD9"
                     /experiment="COORDINATES: cap analysis [ECO:0007248]"
                     /note="transcription start site"
     CDS             24..1664
                     /gene="MARS1"
                     /gene_synonym="CMT2U; ILFS2; ILLD; MARS; METRS; MRS;
                     MTRNS; SPG70; TTD9"
                     /codon_start=1
                     /product="methionine--tRNA ligase, cytoplasmic isoform X2"
                     /protein_id="XP_047284808.1"
                     /db_xref="GeneID:4141"
                     /db_xref="HGNC:HGNC:6898"
                     /db_xref="MIM:156560"
                     /translation="MRLFVSDGVPGCLPVLAAAGRARGRAEVLISTVGPEDCVVPFLT
                     RPKVPVLQLDSGNYLFSTSAICRYFFLLSGWEQDDLTNQWLEWEATELQPALSAALYY
                     LVVQGKKGEDVLGSVRRALTHIDHSLSRQNCPFLAGETESLADIVLWGALYPLLQDPA
                     YLPEELSALHSWFQTLSTQEPCQRAAETVLKQQGVLALRPYLQKQPQPSPAEGRAVTN
                     EPEEEELATLSEEEIAMAVTAWEKGLESLPPLRPQQNPVLPVAGERNVLITSALPYVN
                     NVPHLGNIIGCVLSADVFARYSRLRQWNTLYLCGTDEYGTATETKALEEGLTPQEICD
                     KYHIIHADIYRWFNISFDIFGRTTTPQQTKITQDIFQQLLKRGFVLQDTVEQLRCEHC
                     ARFLADRFVEGVCPFCGYEEARGDQCDKCGKLINAVELKKPQCKVCRSCPVVQSSQHL
                     FLDLPKLEKRLEEWLGRTLPGSDWTPNAQFITRSWLRDGLKPRCITRDLKWGTPVPLE
                     GFEDKVFYVWFDATIGYLSITANYTDQWERWWKNPEQP"
ORIGIN      
        1 atcagcgagg gattcacggc gaaatgagac tgttcgtgag tgatggcgtc ccgggttgct
       61 tgccggtgct ggccgccgcc gggagagccc ggggcagagc agaggtgctc atcagcactg
      121 taggcccgga agattgtgtg gtcccgttcc tgacccggcc taaggtccct gtcttgcagc
      181 tggatagcgg caactacctc ttctccacta gtgcaatctg ccgatatttt tttttgttat
      241 ctggctggga gcaagatgac ctcactaacc agtggctgga atgggaagcg acagagctgc
      301 agccagcttt gtctgctgcc ctgtactatt tagtggtcca aggcaagaag ggggaagatg
      361 ttcttggttc agtgcggaga gccctgactc acattgacca cagcttgagt cgtcagaact
      421 gtcctttcct ggctggggag acagaatctc tagccgacat tgttttgtgg ggagccctat
      481 acccattact gcaagatccc gcctacctcc ctgaggagct gagtgccctg cacagctggt
      541 tccagacact gagtacccag gaaccatgtc agcgagctgc agagactgta ctgaaacagc
      601 aaggtgtcct ggctctccgg ccttacctcc aaaagcagcc ccagcccagc cccgctgagg
      661 gaagggctgt caccaatgag cctgaggagg aggagctggc taccctatct gaggaggaga
      721 ttgctatggc tgttactgct tgggagaagg gcctagaaag tttgcccccg ctgcggcccc
      781 agcagaatcc agtgttgcct gtggctggag aaaggaatgt gctcatcacc agtgccctcc
      841 cttacgtcaa caatgtcccc caccttggga acatcattgg ttgtgtgctc agtgccgatg
      901 tctttgccag gtactctcgc ctccgccagt ggaacaccct ctatctgtgt gggacagatg
      961 agtatggtac agcaacagag accaaggctc tggaggaggg actaaccccc caggagatct
     1021 gcgacaagta ccacatcatc catgctgaca tctaccgctg gtttaacatt tcgtttgata
     1081 tttttggtcg caccaccact ccacagcaga ccaaaatcac ccaggacatt ttccagcagt
     1141 tgctgaaacg aggttttgtg ctgcaagata ctgtggagca actgcgatgt gagcactgtg
     1201 ctcgcttcct ggctgaccgc ttcgtggagg gcgtgtgtcc cttctgtggc tatgaggagg
     1261 ctcggggtga ccagtgtgac aagtgtggca agctcatcaa tgctgtcgag cttaagaagc
     1321 ctcagtgtaa agtctgccga tcatgccctg tggtgcagtc gagccagcac ctgtttctgg
     1381 acctgcctaa gctggagaag cgactggagg agtggttggg gaggacattg cctggcagtg
     1441 actggacacc caatgcccag tttatcaccc gttcttggct tcgggatggc ctcaagccac
     1501 gctgcataac ccgagacctc aaatggggaa cccctgtacc cttagaaggt tttgaagaca
     1561 aggtattcta tgtctggttt gatgccacta ttggctatct gtccatcaca gccaactaca
     1621 cagaccagtg ggagagatgg tggaagaacc cagagcaacc ctaggagctg aggataacta
     1681 taccttggtc agccacctca ttgctacaga gtacctgaac tatgagga
//
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