Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Download features.
Download gene features.
NCBI Reference Sequence: XM_054342875.1
FASTA Graphics
LOCUS XM_054342875 3309 bp mRNA linear PRI 26-AUG-2024 DEFINITION PREDICTED: Homo sapiens sphingomyelin phosphodiesterase 4 (SMPD4), transcript variant X18, mRNA. ACCESSION XM_054342875 VERSION XM_054342875.1 DBLINK BioProject: PRJNA807723 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_060926) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Updated annotation Annotation Name :: GCF_009914755.1-RS_2024_08 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; RefSeqFE; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 08/23/2024 ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..3309 /organism="Homo sapiens" /mol_type="mRNA" /isolate="CHM13" /db_xref="taxon:9606" /chromosome="2" /sex="female" /cell_line="CHM13htert" /tissue_type="hydatidiform mole" /note="haploid cell line" gene 1..3309 /gene="SMPD4" /gene_synonym="NEDMABA; NEDMEBA; NET13; NSMASE-3; NSMASE3; SKNY" /note="sphingomyelin phosphodiesterase 4; Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 4 mRNAs, 22 ESTs, 1052 long SRA reads, 3 Proteins, and 96% coverage of the annotated genomic feature by RNAseq alignments, including 15 samples with support for all annotated introns" /db_xref="GeneID:55627" /db_xref="HGNC:HGNC:32949" /db_xref="MIM:610457" CDS 623..2146 /gene="SMPD4" /gene_synonym="NEDMABA; NEDMEBA; NET13; NSMASE-3; NSMASE3; SKNY" /codon_start=1 /product="sphingomyelin phosphodiesterase 4 isoform X18" /protein_id="XP_054198850.1" /db_xref="GeneID:55627" /db_xref="HGNC:HGNC:32949" /db_xref="MIM:610457" /translation="MGLNLPEVPSALPRRSQPSLMGALGSSVSRASLLGKQQVTLPIP CRAAVPRFVQQKLYLFLQHCFGHWPLDASFRAVLEMWLSYLQPWRYAPDKQAPGSDSQ PRCVSEKWAPFVQENLLMYTKLFVGFLNRALRTDLVSPKHALMVFRVAKVFAQPNLAE MIQKGEQLFLEPELVIPHRQHRLFTAPTFTGSFLSPWPPAVTDASFKVKSHVYSLEGQ DCKYTPMFGPEARTLVLRLAQLITQAKHTAKSISDQCAESPAGHSFLSWLGFSSMDTN GSYTANDLDEMGQDSVRKTDEYLEKALEYLRQIFRLSEAQLRQFTLALGTTQDENGKK QLPDCIVGEDGLILTPLGRYQIINGLRRFEIEYQGDPELQPIRSYEIASLVRTLFRLS SAINHRFAGQMAALCSRDDFLGSFCRYHLTEPGLASRHLLSPVGRRQVAGHTRGPRLS LRFLGSYRTLVSLLLAFFVASLFCVGPLPCTLLLTLGYVLYASAMTLLTERGKLHQP" ORIGIN 1 tgacctcaag tgatctgcct gccttggcct cccaaagtgt tgggattata ggcgtgagcc 61 accgcacctg gccctttctt ccaaaacaat gcaaattcat tgcccaaaga cttaacaata 121 cagatagaga aaaatagcca gccacgatgg ctcatgcttg taatcccagc actttgggag 181 gttgaggcag gcggattgcc tgagctcagg agtttgagac cagcctgggc aacatggcga 241 aacccctgtc tctacaaata caaaaattag cctggtgtgg tggtgtgtgc gcctgtgttc 301 ccagctaccc gggaggctga gatgggagga tcccttaagc cctggaggca gaggctgcag 361 tgagccgaga ccacgacact acagcgcggg tgacagagtg agaccctgtc tcaaaaaaaa 421 gaaaatgcct cccaccccat agctccatct tcagactcag ccacttatct ctggggagtc 481 gttcacgcct actgaggagc atgtgttggt ggtgcgcctg ctgctgaagc acctgcacgc 541 ctttgccaac agcctgaagc cagagcaggc ctcaccctcc gcccactccc acgccaccag 601 ccccctggag gagttcaaac gaatggggct gaacctcccg gaggtgccca gtgctctccc 661 ccggcggagc caaccctcac tgatgggagc cctggggtca tctgtgagca gggcctcctt 721 actgggcaag cagcaggtga ccctccccat cccctgcagg gctgctgtcc cgaggttcgt 781 ccagcagaaa ctctacctct tcttgcagca ttgctttggc cactggcccc tggacgcatc 841 gttcagagct gtcctggaga tgtggctgag ctacctgcag ccgtggcggt acgcgcctga 901 caagcaggct ccgggcagcg actcccagcc ccggtgtgtg tcggagaaat gggcaccctt 961 tgtccaggag aacctgctga tgtacaccaa gttgtttgtg ggctttctga accgcgcgct 1021 ccgcacagac ctggtcagcc ccaagcacgc gctcatggtg ttccgagtgg ccaaagtctt 1081 tgcccagccc aacctggctg agatgattca gaaaggtgag cagctattcc tggagccaga 1141 gctggtcatc ccccaccgcc agcaccgact cttcacggcc cccacattca ctgggagctt 1201 cctgtcaccc tggccaccag cggtcactga tgcctccttc aaggtgaaga gccacgtcta 1261 cagcctggag ggccaggact gcaagtacac cccgatgttt gggcccgagg cccgcaccct 1321 ggtcctgcgc ctcgctcagc tcatcacaca ggccaaacac acagccaagt ccatctccga 1381 ccagtgtgcg gagagcccgg ctggccactc cttcctctca tggctgggct ttagctccat 1441 ggacaccaat ggctcctaca cagccaacga cctggacgag atggggcaag acagtgtccg 1501 gaagacagat gaatacctgg agaaggccct ggagtacctg cgccagatat tccggctcag 1561 cgaagcgcag ctcaggcagt tcacactcgc cttgggcacc acccaggatg agaatggaaa 1621 aaagcaactc cccgactgca tcgtgggtga ggacggactc atccttacgc ccctggggcg 1681 gtaccagatc atcaatgggc tgcgaaggtt tgaaattgag taccaggggg acccggagct 1741 gcagcccatc cggagctatg agatcgccag cttggtccgc acactcttta ggctgtcgtc 1801 tgccatcaac cacagatttg caggacagat ggcggctctg tgttcccggg atgacttcct 1861 cggcagcttc tgtcgctacc acctcacaga acctgggctg gccagcaggc acctgctgag 1921 ccctgtgggg cggaggcagg tggccggcca cacccgcggc cccaggctca gcctgcgctt 1981 cctgggcagt taccggacgc tggtctcgct gctgctggcc ttcttcgtgg cctctctgtt 2041 ctgcgtcggg cccctcccat gcacgctgct gctcaccctg ggctatgtcc tctacgcctc 2101 tgccatgaca ctgctgaccg agcgggggaa gctgcaccag ccctgaaggt gtcagctgcc 2161 ttcagagcag gctggaggga tttgccacac agccccaccc ttgggctgag aggacctggg 2221 aagcccctcc aggagggaac acggtcatcc tcgggcttct ggagcggggt tcctgcagcc 2281 gcagaggcat ctggaggaaa cgcaaccaag aaaggaaggc aggtgggccc cagcaaagga 2341 gtagctgcca gggctcaaca gctacgctct gtgacagcgc agagctcagc ggcggccttt 2401 ccctccctcc gccaaggact cacggccaag ccagctctcg gggccttttt tccactgccc 2461 atttggctac tctgctgcac caagcttggg agccagcctg ccaacagcca cctgggcctg 2521 gcctccccac tggctggcct tgaggttggc agagtgggtt gtggcgcttc ctctctctgt 2581 gtgggaccag gacagtggct taagtctcca ctccaggaaa gaatcaaagt ttctagagtt 2641 gtgagaaaac cagagagtgg ctgtcctgat tcttcactgt gaggggcgtt cttcatgttc 2701 tcccagctgt tccaagactg ggccgtagaa ttccatgttt caggagccta agaccctccc 2761 agagcccagg ggcttcaccg cagaccccaa gccattgagc acatcaccca aagcagtggc 2821 caacatcgcg gacccctgtg ccttgtcaca gatgggtgct ggtcctcagg cgttggggac 2881 actgctgggt cgatggggtc ggattctgcc agtttctgct ctgcagccaa agatggtcag 2941 aagcattgtc acttcagtaa catcaagtgc tcaaagacat ggcaaccgtt cagtggtact 3001 taagtattca aaatatacaa ctacagattc tctgacagaa accagcacgg ggtcttcacc 3061 ttcattcacc ccacaggcga catgcgaggg agaacagcat ctcagtggtg atttccaaac 3121 caagcctttg ttttcggtgt ggggttttgg gggtttgctt taatgttttt gaaattgtaa 3181 atgttgggct ttgtattttg atgtaaactg agcataatgg cattttaggg cctgtgacca 3241 aaaatgaagc ttgtaacgac catggatctg aataaacatg tccttgcttc tgagtcttct 3301 ggcacctgg //
Whole sequence Selected region from: to:
All features Gene, RNA, and CDS features only
SNP
Show sequence Show reverse complement Show gap features
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on