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Inhibition of mouse thymus 6His-sumo-tagged G9a (969 to 1263 residues) expressed in Escherichia coli BL21 (DE3) using histone H3 as substrate incubated for 30 mins by MALDI-TOF-MS analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of His-sumo-tagged BALB/c mouse thymus histone methyltransferase G9a (969 to 1263 residues) catalytic domain expressed in Escherichia coli BL21 (DE3) using histone H3 (1 to 24 residues) as substrate assessed as reduction in H3K9me2 levels at 10 uM after 1 hr in presence of SAM by MALDI-TOF-mass spectroscopic analysis
Inhibition of His-sumo-tagged BALB/c mouse thymus histone methyltransferase G9a (969 to 1263 residues) catalytic domain expressed in Escherichia coli BL21 (DE3) by SPR assay
Assay data:1 Active, 2 Tested
Inhibition of His-sumo-tagged BALB/c mouse thymus histone methyltransferase G9a (969 to 1263 residues) using biotin labeled peptide substrate after 30 mins in presence of [methyl-3H]-SAM by microbeta scintillation counting
Inhibition of His-sumo-tagged BALB/c mouse thymus histone methyltransferase G9a (969 to 1263 residues) using biotin labeled peptide substrate at 10 uM after 30 mins in presence of [methyl-3H]-SAM by microbeta scintillation counting relative to control
Assay data:6 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of His-sumo-tagged BALB/c mouse thymus histone methyltransferase G9a (969 to 1263 residues) catalytic domain expressed in Escherichia coli BL21 (DE3) assessed as response unit at 10 to 100 uM by SPR assay
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
Inhibition of mouse Histone-lysine N-methyltransferase G9a
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Inhibition of mouse G9a
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