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The compound was tested for inhibitory activity against 5-lipoxygenase in mouse macrophages
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
In vivo inhibition of 5-lipoxygenase (LTC4) in the mouse zymosan peritonitis assay at an oral dose of 30 mg/Kg
Assay data:6 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibitory concentration against 5-lipoxygenase from mouse macrophage
Assay data:11 Tested
Inhibition of 5-lipoxygenase in mouse macrophages.
Assay data:8 Active, 8 Activity ≤ 1 µM, 9 Tested
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Inhibitory activity against lipoxygenase-2 in mice
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibitory activity against murine lipoxygenase-2.
Assay data:10 Active, 2 Activity ≤ 1 µM, 17 Tested
Inhibition of 5-lipoxygenase from mouse macrophage
Assay data:11 Active, 1 Activity ≤ 1 nM, 11 Activity ≤ 1 µM, 11 Tested
Inhibition of 5-LO in mouse BMM cells assessed as formation of LTC4 after 30 mins by enzyme immunoassay
Assay data:4 Active, 1 Activity ≤ 1 µM, 4 Tested
Inhibition of leukotriene formation in A-23187-stimulated mouse whole blood using LTB4 specific RIA ex vivo, activity expressed as percent of control.
Assay data:21 Tested
Inhibition of 5-lipoxygenase-mediated platelet activating factor induced thrombosis in male mice
Assay data:9 Tested
Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassay
Assay data:13 Active, 2 Activity ≤ 1 µM, 14 Tested
Inhibition of 5-LOX in calcium ionophore A23187-stimulated NMRI mouse macrophage assessed as inhibition of LTC4 production preincubated for 60 mins before stimulation measured after 2 hrs by ELISA
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
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