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Agonist activity at EphA4 in B6-Cg-Tg(Hlxb9-GFP)1Tmj/J (Hb9-GFP) mouse spinal cord motor neurons assessed as induction of growth cone collapse at 1 to 10 uM in presence of ephrin A1-Fc by rhodamine-coupled phalloidin dye based inverted fluorescent microscopic method
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Agonist activity at EphA4 in B6-Cg-Tg(Hlxb9-GFP)1Tmj/J (Hb9-GFP) mouse spinal cord motor neurons assessed as induction of growth cone collapse at 1 to 10 uM by rhodamine-coupled phalloidin dye based inverted fluorescent microscopic method
Agonist activity at EphA4 in B6-Cg-Tg(Hlxb9-GFP)1Tmj/J (Hb9-GFP) mouse primary spinal cord motor neuron cells assessed as protein phosphorylation at Y20 residues at 1 to 10 uM incubated for 30 mins by Western blotting analysis
Displacement of biotinylated ephrin-A1-Fc from mouse EphA4 Fc preincubated for 1 hr followed by ephrin-A1-FC addition and measured after 4 hrs by ELISA
Antagonist activity against mouse EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by ELISA
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Mouse EPH receptor A4 (Type XIII RTKs: Ephrin receptor family)
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Counter Screen for Placental Alkaline Phosphatase-based Assays Positives
Assay data:134 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Colorimetric assay for HTS discovery of chemical inhibitors of EphA4 receptor antagonists
Assay data:80 Active, 3 Activity ≤ 1 µM, 61808 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
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