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Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
qHTS of IL-2 Activators
Assay data:238 Active, 364943 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same Project
qHTS of IL-2 Activators: Summary
SummaryRelated BioAssays by DepositorRelated BioAssays by Same Project
The compound was evaluated in vitro for the immunosuppressive activity in interleukin-2 by interleukin-2 reporter gene assay (IL2-RGA)
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Tested in vitro for inhibition of Interleukin-2 (IL-2) release; Active
Assay data:1 Active, 1 Tested
SummaryCompounds, Active
Tested in vitro for inhibition of Interleukin-2 (IL-2) release; 2-3 times less active than compound 1
Assay data:2 Tested
Summary
Tested in vitro for inhibition of Interleukin-2 (IL-2) release; 100 times less active than cyclosporin A
Assay data:3 Tested
Percent inhibition of interleukin-2 production by compound was measured after 8 hours of oral administration in mice
Assay data:4 Tested
Percent inhibition of interleukin-2 production by compound was measured after 18 hours of oral administration in mice
Effective concentration to suppress interleukin-2 production was measured after 2.5 hours of oral administration in mice
Ability to suppress interleukin-2 production was determined after 2.5 hours of oral administration in mice
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