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Inhibitory activity of Monoamine oxidase at mouse forebrain homogenate by displacing [14C]5-HT
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
The ability (25 umol/kg/day) to inactivate monoamine oxidase A(MAO-A) was tested on brain mitochondrial membranes of mice, for 3 day
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
The ability of the compound(25 umol/kg/day) to inactivate monoamine oxidase A(MAO-A) was tested on brain mitochondrial membranes of mice, for 3 day.
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Tested for in vitro antagonistic activity against Monoamine oxidase
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibitory activity against Monoamine oxidase at the selectivity factor of 4000
Compound was tested for inhibition of Monoamine oxidase (MAO); Inactive
Assay data:3 Tested
Tested for pargyline-induced inhibition of MAO-catalyzed oxidation in rat brain mitochondria (Specific inhibitor = Pargyline hydrochloride at 2.5 uM) (Control = 16.68)
Percent inhibition of MAO-catalyzed oxidation in rat brain mitochondria induced by pargyline
Assay data:9 Tested
Compound was injected ip 1 hr prior to 90 mg/kg iv of 5-HT (serotonin) for evaluation of tremor in mcie
Compound was injected ip 1 hr prior to 90 mg/kg iv of 5-HT (serotonin) for evaluation of head twitches in mcie
Compound was injected ip 1 hr prior to 90 mg/kg iv of 5-HT (serotonin) for evaluation of abduction in mice
Ratio of IC50 against mouse brain MAO-A and MAO-B
Assay data:11 Tested
Displacement of [14C]5-HT from mouse forebrain homogenate Monoamine oxidase
Inhibition of Monoamine oxidase at mouse forebrain homogenate by displacing [14C]PEA (phenethylamine)
Inhibitory activity of Monoamine oxidase at mouse forebrain homogenate by displacing [14C]PEA (phenethylamine)
Inhibitory activity of Monoamine oxidase at mouse forebrain homogenate by displacing [14C]PEA
Assay data:16 Tested
Inhibitory activity of Monoamine oxidase at mouse forebrain homogenate by displacing [14C]5-HT (serotonin)
The ability of the compound(25 umol/kg/day) to inactivate monoamine oxidase (MAO) was tested on brain mitochondrial membranes of mice, for 3 days.
Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested
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