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Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Summary
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
Concentration required against dynamin-1 GTPase activity of sheep brain.
Assay data:14 Active, 35 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Concentration required against dynamin-1 GTPase activity of sheep brain; increased dynamin I GTPase activity at 30 uM.
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibitory activity against dynamin1 GTPase expressed in sheep brain
Assay data:14 Active, 133 Tested
Inhibition of dynamin 1-mediated endocytosis internalization of Tf-A594 in human U2OS cells pretreated for 30 mins
Assay data:1 Active, 5 Tested
Inhibition of GTPase activity of Dynamin 1
Assay data:2 Active, 17 Tested
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
SummaryPubMed Citation
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Inhibition of dynamin1-mediated endocytosis in human U2OS cells assessed as inhibition of Texas red-Tf uptake incubated for 30 mins prior to Texas red-Tf addition measured after 8 mins by receptor-mediated endocytosis assay
Assay data:2 Active, 4 Tested
Inhibition of dynamin1-mediated endocytosis in human U2OS cells assessed as inhibition of Texas red-Tf uptake incubated up to 300 uM for 30 mins prior to Texas red-Tf addition measured after 8 mins by receptor-mediated endocytosis assay
Assay data:8 Tested
Ring stabilizer activity at recombinant dynamin 1 dimeric GG2 form (unknown origin) assessed as stimulation of GTPase activity using 200 to 1000 nM full-length dynamin
Assay data:3 Tested
SummaryRelated BioAssays by Target
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
Inhibition of Dynamin 1 in serum-starved human U2OS cells assessed as inhibition of clathrin-mediated Alexa-495-cojugated transferrin uptake pretreated for 30 mins by high-content imaging method
Assay data:5 Tested
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