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Compound was tested for the binding affinity towards muscarinic acetylcholine receptor in mouse brain membrane
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Analgesic activity as percentage analgesic efficacy on male albino swiss-webster mice with the hotplate test
Assay data:25 Tested
Analgesic activity after subcutaneous administration in male albino Swiss-Webster mice with the hotplate test
Ability to inhibit binding of [3H]QNB to Muscarinic acetylcholine receptor in cultured N4TG1 neuroblastoma cells at 1e-8 to 1e-3 M
Assay data:4 Tested
Ability (10 ug/kg) to inhibit binding of [125I]iododexetimide to muscarinic receptor in mice
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of the specific binding of [3H]QNB to Muscarinic acetylcholine receptor
Assay data:8 Tested
Hill coefficient for binding of [3H]QNB to Muscarinic acetylcholine receptor
Assay data:2 Tested
Compound was tested for the binding affinity towards muscarinic receptor in mouse brain membrane
Dissociation constant towards Muscarinic acetylcholine receptor was determined by using [3H]4NMPB as radioligand
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Antagonist activity at muscarinic receptor in BALB/c mouse MSC assessed as inhibition of carbachol-induced increase in cell viability at 10'-10M incubated for 24 hrs by Cell-titer 96 aqueous one solution reagent based assay
Percent inhibition of radioligand [3H]QNB binding to muscarinic receptor at 10 uM concentration
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
Activity at muscarinic receptor in BALB/c mouse MSC assessed as reduction in cell viability at 10'-4M incubated for 24 hrs by Cell-titer 96 aqueous one solution reagent based assay
Assay data:2 Active, 2 Tested
Activity at muscarinic receptor in BALB/c mouse MSC assessed as increase in cell viability at 10'-10M incubated for 24 hrs by Cell-titer 96 aqueous one solution reagent based assay
Antagonist activity at muscarinic receptor in BALB/c mouse MSC assessed as inhibition of carbachol-induced increase in cell viability at 10'-4 to 10'-10M incubated for 24 hrs by Cell-titer 96 aqueous one solution reagent based assay
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