Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Inhibition of TLR4-mediated NF-kappaB signaling pathway in BALB/c mouse RAW264.7 cells assessed as suppression of LPS-stimulated TNF-alpha production at 2.5 to 10 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of TLR4 in BALB/c mouse RAW264.7 cells assessed as suppression of LPS-induced IkappaB-alpha phosphorylation at 10 to 50 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis
Inhibition of TLR4 in LPS-stimulated BALB/c mouse RAW264.7 cells at 10 to 50 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis
Inhibition of TLR4-mediated NF-kappaB signaling pathway in BALB/c mouse RAW264.7 cells assessed as suppression of LPS-stimulated PGE2 production at 0.5 to 5 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis in presence of HEA
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of TLR4-mediated NF-kappaB signaling pathway in BALB/c mouse RAW264.7 cells assessed as suppression of LPS-stimulated PGE2 production at 0.5 to 5 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis in presence of adenosine
Inhibition of TLR4-mediated NF-kappaB signaling pathway in BALB/c mouse RAW264.7 cells assessed as suppression of LPS-stimulated PGE2 production at 0.5 to 5 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis in presence of cordycepin
Inhibition of TLR4-mediated NF-kappaB signaling pathway in BALB/c mouse RAW264.7 cells assessed as suppression of LPS-stimulated PGE2 production at 2.5 to 10 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis
Assay data:2 Active, 2 Tested
Inhibition of TLR4-mediated NF-kappaB signaling pathway in BALB/c mouse RAW264.7 cells assessed as suppression of LPS-stimulated PGE2 production at 1 to 10 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis
Inhibition of TLR4-mediated NF-kappaB signaling pathway in BALB/c mouse RAW264.7 cells assessed as suppression of LPS-stimulated TNF-alpha production at 0.5 to 5 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis in presence of HEA
Inhibition of TLR4-mediated NF-kappaB signaling pathway in BALB/c mouse RAW264.7 cells assessed as suppression of LPS-stimulated TNF-alpha production at 0.5 to 5 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis in presence of adenosine
Inhibition of TLR4-mediated NF-kappaB signaling pathway in BALB/c mouse RAW264.7 cells assessed as suppression of LPS-stimulated TNF-alpha production at 0.5 to 5 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis in presence of cordycepin
Inhibition of TLR4-mediated NF-kappaB signaling pathway in BALB/c mouse RAW264.7 cells assessed as suppression of LPS-stimulated TNF-alpha production at 5 to 10 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis
Inhibition of TLR4 in BALB/c mouse RAW264.7 cells assessed as suppression of LPS-induced COX2 expression at 10 to 50 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis
Inhibition of TLR4-mediated NF-kappaB signaling pathway in BALB/c mouse RAW264.7 cells assessed as suppression of LPS-stimulated TNF-alpha production at 1 to 10 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis
Potency index, ratio of IC50 for (+)-naltrexone to IC50 for test compound against TLR4 in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by 2,3-diaminonaphthalene dye based assay
Assay data:10 Tested
Antagonist activity against TLR4 in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production at >100 uM incubated for 24 hrs by 2,3-diaminonaphthalene dye based assay
Antagonist activity against TLR4 in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by 2,3-diaminonaphthalene dye based assay
Assay data:11 Active, 19 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Secondary screen NFkB readout
Assay data:1483 Active, 3847 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Secondary screen TNF readout
Assay data:2176 Active, 3847 Tested
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on