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Inhibition of p53-dependent transcription of puma in gamma-stimulated mouse thymocyte
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of p53-mediated increase in p21/WAF1 level at 300 nM
Assay data:2 Active, 3 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of p53-mediated increase in p21/WAF1 level at 30 nM
Assay data:1 Active, 2 Tested
Induction of p53-dependent transcriptional activity in mouse JB6 Cl41 cells at 12.5 uM after 6 hrs
Inhibition of p53-mediated transcriptional activity in mouse JB6 Cl41 cells at 125 to 500 nM by luciferase reporter gene assay
Inhibition of p53-mediated transcriptional activity in mouse JB6 Cl41 cells after 24 hrs by luciferase reporter gene assay
Inhibition of p53-mediated transcriptional activity in mouse JB6 Cl41 cells at 375 to 500 nM after 6 hrs by luciferase reporter gene assay relative to control
Inhibition of p53-mediated transcriptional activity in mouse JB6 Cl41 cells at 125 to 250 nM after 24 hrs by luciferase reporter gene assay relative to control
Inhibition of p53-induced apoptosis in gamma irradiated mouse thymocytes at 10 uM after 24 hrs by trypan blue assay
Inhibition of p53-mediated apoptosis in mouse fibroblast assessed as cell survival at 10 uM after 24 hrs by methylene blue assay
Assay data:1 Active, 1 Tested
Inhibition of p53-dependent transcription of puma in mouse thymocyte
Effect on p53 phosphorylation in mouse primary mesangial cells up to 2.2 uM by Western blot method
Binding affinity to p53 in gamma irradiated mouse thymocyte assessed as cytosolic p53 concentration at 10 uM after 2 hrs
Binding affinity to p53 in gamma irradiated mouse thymocyte assessed as mitochondrial p53 concentration at 10 uM after 2 hrs
Binding affinity to p53 in gamma irradiated mouse thymocyte assessed as cytosolic Bcl-2 concentration at 10 uM after 2 hrs
Binding affinity to p53 in gamma irradiated mouse thymocyte assessed as cytosolic p21 concentration at 10 uM after 2 hrs
Binding affinity to p53 in gamma irradiated mouse thymocyte assessed as cytosolic caspase 8 concentration at 10 uM after 2 hrs
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Inhibition of p53-dependent transcriptional activity in tumor promotion-sensitive mouse JB6 Cl41 cells after 12 hrs by luciferase-based method
Assay data:10 Active, 11 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
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