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Agonist activity at P2X3R in mouse TG sensory neurons assessed as induction of channel current at 10 uM at -65 mV holding potential by whole cell voltage clamp method relative to alpha,beta-meATP
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at P2X3R in mouse TG sensory neurons assessed as induction of channel current at 1 uM at -65 mV holding potential by whole cell voltage clamp method relative to alpha,beta-meATP
Assay data:1 Tested
Antagonist activity at P2X3R in mouse TG sensory neurons assessed as inhibition of P2X3R agonist alpha,beta-meATP-induced current at 1 uM at -65 mV holding potential by whole cell voltage clamp method relative to control
Antagonist activity at P2X3R in mouse TG sensory neurons assessed as inhibition of P2X3R agonist alpha,beta-meATP-induced current at -65 mV holding potential by whole cell voltage clamp method
Assay data:5 Active, 6 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Antagonist activity at P2X3 receptor in C57Bl/6 wild type mouse trigeminal ganglion sensory neurons assessed as desensitization of alpha,beta-methyleneATP-induced current at 100 uM after 20 secs by patch clamp technique
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Antagonist activity at P2X3 receptor in C57Bl/6 wild type mouse trigeminal ganglion sensory neurons assessed as desensitization of alpha,beta-methyleneATP-induced current at 1 uM after 20 secs by patch clamp technique
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