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Agonist activity at mouse FFA1 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at GPR40 in mouse MIN6 cells assessed as increase in glucose-stimulated insulin secretion at 10 uM measured after 2 hrs by ELISA relative to control
Assay data:4 Tested
Agonist activity at mouse GPR40
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at GPR40 in mouse MIN6 cells assessed as increase in 17 mM glucose-stimulated insulin secretion at 1 and 10 uM after 2 hrs by ELISA relative to glucose
Assay data:5 Tested
Agonist activity at mouse GPR40 assessed as increase in IP1 accumulation after 60 mins by HTRF assay
Assay data:2 Tested
Partial agonist activity at mouse free fatty acid receptor 1 expressed in HEK293 cells assessed as inositol phosphate 1 accumulation incubated for 30 mins
Agonist activity at mouse GPR40 in presence of 0.01% human serum albumin
Antagonist activity against mouse GPR40
SummaryCompounds, ActiveRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
Agonist activity against mouse GPR40 expressed in U2OS cells by FLIPR/summary (Abse5) assay
Agonist activity at GPR40 in mouse MIN6 cells assessed as increase in glucose-stimulated insulin secretion measured after 2 hrs by ELISA
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Agonist activity at mouse FFA1 receptor transfected in human T-REX-293 cells measured for 74 secs by calcium mobilization assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Agonist activity at mouse FFA1
Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assay
Assay data:19 Active, 15 Activity ≤ 1 µM, 20 Tested
Activation of FFA1 in mouse islets assessed as glucose-dependent insulin secretion
Agonist activity at mouse GPR40 expressed in HEK293 cells
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