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Inhibition of NPC1L1-mediated cholesterol-methyl-beta-cyclodextrin accumulation in mouse RAW264.7 cells assessed as decrease in foam cell formation by measuring decrease in MDA level
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of NPC1L1-mediated cholesterol-methyl-beta-cyclodextrin accumulation in mouse RAW264.7 cells assessed as decrease in foam cell formation by measuring decrease in LDH level
Inhibition of NPC1L1-mediated cholesterol-methyl-beta-cyclodextrin accumulation in mouse RAW264.7 cells assessed as decrease in foam cell formation by measuring decrease in MDA level at 30 uM relative to control
Assay data:2 Tested
Inhibition of NPC1L1-mediated cholesterol-methyl-beta-cyclodextrin accumulation in mouse RAW264.7 cells assessed as decrease in foam cell formation by measuring decrease in LDH level at 30 uM relative to control
Inhibition of NPC1L1-mediated cholesterol-methyl-beta-cyclodextrin accumulation in mouse RAW264.7 cells incubated for 72 hrs by Oil Red O/hematoxyline staining based microscopic analysis
Inhibition of NPC1L1 in mouse RAW264.7 cells assessed as decrease in choleserol-D7 absorption at 30 uM after 72 hrs by LC-MS/MS analysis relative to control
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoazetidin-2-yl)phenoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid from mouse NCP1L1 expressed in mouse brush border membrane
Assay data:4 Tested
Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoazetidin-2-yl)phenoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid from recombinant mouse NPC1L1 expressed in HEK cells by single tube filtration assay
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
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