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Inhibition of IRAP in C57Bl/6 mouse CD11b-positive dendritic cells assessed as reduction of IRAP-dependent cross-presentation activity by measuring IL2 level in CD8+ T-cells isolated from lymph nodes of Rag-1-/- C57Bl/6 OT-I mouse at 3 to 3333 nM pre-incubated for 60 mins followed by addition of ovalbumin measured after 6 hrs by sandwich ELISA
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of IRAP in C57Bl/6 mouse CD8 alpha-positive cells assessed as reduction of IRAP-dependent cross-presentation activity by measuring IL2 level in CD8+ T-cells isolated from lymph nodes of Rag-1-/- C57Bl/6 OT-I mouse at 3 to 3333 nM pre-incubated for 60 mins followed by addition of ovalbumin measured after 6 hrs by sandwich ELISA
MLPCN IRAP Measured in Biochemical System Using Plate Reader - 7016-03_Inhibitor_Dose_DryPowder_Activity_Set3
Assay data:1 Active, 24 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
MLPCN IRAP Measured in Biochemical System Using Plate Reader - 7016-03_Inhibitor_Dose_DryPowder_Activity_Set2
Assay data:60 Tested
SummaryRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
MLPCN IRAP Measured in Biochemical System Using Plate Reader - 7016-03_Inhibitor_Dose_CherryPick_Activity_Set2
Assay data:9 Active, 1 Activity ≤ 1 µM, 151 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
MLPCN IRAP Measured in Biochemical System Using Plate Reader - 7016-03_Inhibitor_Dose_CherryPick_Activity
Assay data:61 Active, 40 Activity ≤ 1 µM, 151 Tested
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