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Adenylate cyclase activity of the compound, expressed as effective concentration
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of dopamine sensitive adenylate cyclase at 10 uM
Assay data:3 Tested
Inhibition of dopamine sensitive adenylate cyclase at 1 uM; No inhibition
Assay data:4 Tested
Inhibition of dopamine sensitive adenylate cyclase at 1 uM
Assay data:1 Tested
Inhibition of dopamine sensitive adenylate cyclase at 0.1 uM
Inhibition of dopamine sensitive adenylate cyclase at 0.01 uM
The compound was tested for adenylate cyclase activity in rat corpus striatum
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibitory concentration against Dopamine sensitive adenylate cyclase in rats
Assay data:4 Active, 2 Activity ≤ 1 µM, 4 Tested
Adenylate cyclase stimulation; Inactive up to 100 uM.
Assay data:21 Tested
Tested for ability to stimulate dopamine sensitive adenylate cyclase in rat caudate homogenate
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
Effective concentration required for 50% conversion of [alpha-32P]ATP to cyclic 3',5'-AMP.
Inhibition of dopamine sensitive adenylate cyclase at 10 uM; No inhibition
Adenylate cyclase activity measured as 50% inhibitory concentration; i.a means inactive up to 10 uM
Adenylate cyclase activity measured as 50% inhibitory concentration
Assay data:14 Active, 1 Activity ≤ 1 nM, 11 Activity ≤ 1 µM, 14 Tested
Ability (50 uM) to stimulate dopamine sensitive adenylate cyclase from rat corpus striatum in the presence of excess ATP
Assay data:2 Tested
Ability (250 uM) to stimulate dopamine sensitive adenylate cyclase from rat corpus striatum in the presence of excess ATP
Adenylate cyclase activity measured as percentage stimulation at (20uM)
Adenylate cyclase activity measured as percentage stimulation at 20 uM
Adenylate cyclase activity measured as percentage stimulation at (1 uM)
Adenylate cyclase activity measured as percentage stimulation
Assay data:10 Tested
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