BioAssay by Target (List) for Gene (Select 25432) - PubChem BioAssay - NCBI

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Select item 628561.

Compound was tested in vitro for its ability to displace [3H]spiroperidol from labeled dopamine receptors of corpus striatum

Source:: ChEMBL

Protein Targets:: D; ...
Total:: 5

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 62856

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 628702.

Inhibitory activity against [3H]NPA binding (0.45) to dopamine receptors in striata of female wistar rats

Source:: ChEMBL

Protein Targets:: D; ...
Total:: 5

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 62870

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 628693.

Inhibitory activity against [3H]NPA binding (0.45) to dopamine receptor in striata of female wistar rats

Source:: ChEMBL

Protein Targets:: D; ...
Total:: 5

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 62869

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 628684.

Inhibition of [3H]spiperone binding to dopamine receptor from rat corpus striatal membranes

Source:: ChEMBL

Protein Targets:: D; ...
Total:: 5

Assay data:25 Active, 36 Activity ≤ 1 µM, 36 Tested

AID:: 62868

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 628675.

Inhibition of [3H]spiroperidol binding to rat striatal membrane using 0.5 nM ligand.

Source:: ChEMBL

Protein Targets:: D; ...
Total:: 5

Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested

AID:: 62867

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 628666.

In vitro inhibition of [3H]haloperidol (HPD) binding to dopamine (DA) receptor of rat striatal membranes

Source:: ChEMBL

Protein Targets:: D; ...
Total:: 5

Assay data:9 Active, 8 Activity ≤ 1 µM, 9 Tested

AID:: 62866

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 628657.

In vitro binding affinity towards dopamine receptor was determined in rat striatal membrane using [3H]spiroperidol as the radioligand

Source:: ChEMBL

Protein Targets:: D; ...
Total:: 5

Assay data:8 Active, 6 Activity ≤ 1 µM, 8 Tested

AID:: 62865

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 628648.

In vitro affinity to dopamine receptor using [3H]NPAD as radioligand in rat striatal membranes

Source:: ChEMBL

Protein Targets:: D; ...
Total:: 5

Assay data:3 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested

AID:: 62864

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 628639.

In vitro affinity to dopamine receptor using [3H]HPD as radioligand in rat striatal membranes

Source:: ChEMBL

Protein Targets:: D; ...
Total:: 5

Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested

AID:: 62863

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 6286210.

In vitro affinity for dopamine receptor by displacement of [3H]- apomorphine in rat striatal membranes

Source:: ChEMBL

Protein Targets:: D; ...
Total:: 5

Assay data:8 Active, 8 Activity ≤ 1 µM, 8 Tested

AID:: 62862

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 6286111.

Evaluated for the inhibition of binding of [3H]DA (dopamine) to dopamine receptor in rat brain homogenate

Source:: ChEMBL

Protein Targets:: D; ...
Total:: 5

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 62861

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 6286012.

Concentration of compound for 50% displacement of [3H]spiperone from Dopamine receptor in rat brain

Source:: ChEMBL

Protein Targets:: D; ...
Total:: 5

Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested

AID:: 62860

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 6285913.

Concentration inhibiting the specific binding of [3H]spiroperidol by 50%

Source:: ChEMBL

Protein Targets:: D; ...
Total:: 5

Assay data:21 Active, 12 Activity ≤ 1 µM, 21 Tested

AID:: 62859

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 6285814.

Concentration inhibiting the specific binding of [3H]naloxone by 50% in the presence of NaCl

Source:: ChEMBL

Protein Targets:: D; ...
Total:: 5

Assay data:11 Active, 8 Activity ≤ 1 µM, 11 Tested

AID:: 62858

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 6285715.

Concentration inhibiting the specific binding of [3H]naloxone by 50% in the absence of NaCl

Source:: ChEMBL

Protein Targets:: D; ...
Total:: 5

Assay data:11 Active, 8 Activity ≤ 1 µM, 11 Tested

AID:: 62857

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 6287116.

Inhibitory activity against dopamine receptor in rat striatal membranes

Source:: ChEMBL

Protein Targets:: D; ...
Total:: 5

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 62871

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 6273917.

Compound was tested in vitro for its ability to displace [3H]spiroperidol from labeled dopamine receptors of corpus striatum

Source:: ChEMBL

Protein Targets:: D; ...
Total:: 5

Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested

AID:: 62739

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 6273818.

Compound was tested in vitro for its ability to displace [3H]spiroperidol from labeled Dopamine receptor of corpus striatum

Source:: ChEMBL

Protein Targets:: D; ...
Total:: 5

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 62738

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 6273719.

Ability to displace [3H]spiroperidol from labeled Dopamine receptor of corpus striatum

Source:: ChEMBL

Protein Targets:: D; ...
Total:: 5

Assay data:11 Active, 11 Activity ≤ 1 µM, 11 Tested

AID:: 62737

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 6273620.

Affinity for Dopamine receptors in the rat striatum using [3H]spiroperidol displacement.

Source:: ChEMBL

Protein Targets:: D; ...
Total:: 5

Assay data:18 Active, 21 Activity ≤ 1 µM, 21 Tested

AID:: 62736

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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BioAssays with protein sequences specified as targets

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Activity (IC50, etc) ≤ 1 nM (13)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (90)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

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BioAssays extracted from the literature

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