BioAssay by Target (List) for Gene (Select 26357) - PubChem BioAssay - NCBI

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Select item 6814491.

TP_TRANSPORTER: Flow cytometry in lymphocytes from Mdr1a/b-/- mice

Source:: ChEMBL

Protein Target:: Broad substrate specificity ATP-binding cassette transporter ABCG2

Assay data:1 Tested

AID:: 681449

Summary PubMed Citation Related BioAssays by Target

Select item 6796792.

TP_TRANSPORTER: transepithelial transport of PhIP (basal to apical) in Bcrp1-expressing MDCKII cells

Source:: ChEMBL

Protein Target:: Broad substrate specificity ATP-binding cassette transporter ABCG2

Assay data:2 Tested

AID:: 679679

Summary PubMed Citation Related BioAssays by Target

Select item 6797813.

TP_TRANSPORTER: transepithelial transport in Bcrp-expressing MDCKII cells

Source:: ChEMBL

Protein Target:: Broad substrate specificity ATP-binding cassette transporter ABCG2

Assay data:2 Tested

AID:: 679781

Summary PubMed Citation Related BioAssays by Target

Select item 6797824.

TP_TRANSPORTER: transepithelial transport (basal to apical) in Bcrp1-expressing MDCKII cells

Source:: ChEMBL

Protein Target:: Broad substrate specificity ATP-binding cassette transporter ABCG2

Assay data:2 Tested

AID:: 679782

Summary PubMed Citation Related BioAssays by Target

Select item 6812735.

TP_TRANSPORTER: transepithelial transport (basal to apical) in Bcrp1-expressing LLC-PK1 cells

Source:: ChEMBL

Protein Target:: Broad substrate specificity ATP-binding cassette transporter ABCG2

Assay data:1 Tested

AID:: 681273

Summary PubMed Citation Related BioAssays by Target

Select item 6812746.

TP_TRANSPORTER: transepithelial transport (basal to apical) in BCRP-expressing MDCKII cells

Source:: ChEMBL

Protein Target:: Broad substrate specificity ATP-binding cassette transporter ABCG2

Assay data:1 Tested

AID:: 681274

Summary PubMed Citation Related BioAssays by Target

Select item 6812757.

TP_TRANSPORTER: transcellular transport in MDCKII

Source:: ChEMBL

Protein Target:: Broad substrate specificity ATP-binding cassette transporter ABCG2

Assay data:1 Tested

AID:: 681275

Summary PubMed Citation Related BioAssays by Target

Select item 6812768.

TP_TRANSPORTER: intracellular accumulation in LY and LY/NR2 cells

Source:: ChEMBL

Protein Target:: Broad substrate specificity ATP-binding cassette transporter ABCG2

Assay data:1 Tested

AID:: 681276

Summary PubMed Citation Related BioAssays by Target

Select item 6812779.

TP_TRANSPORTER: inhibition of Topotecan transepithelial transport (basal to apical)(Topotecan: 10uM, GF120918:10uM) in Bcrp1-expressing LLC-PK1 cells

Source:: ChEMBL

Protein Target:: Broad substrate specificity ATP-binding cassette transporter ABCG2

Assay data:1 Tested

AID:: 681277

Summary PubMed Citation Related BioAssays by Target

Select item 68127810.

TP_TRANSPORTER: inhibition of Topotecan transepithelial transport (basal to apical) in Bcrp1-expressing LLC-PK1 cells

Source:: ChEMBL

Protein Target:: Broad substrate specificity ATP-binding cassette transporter ABCG2

Assay data:1 Tested

AID:: 681278

Summary PubMed Citation Related BioAssays by Target

Select item 68127911.

TP_TRANSPORTER: increase in mitoxantrone intracellular accumulation (Mitoxantrone: 20 uM, GF120918: 2 uM) in MEF3.8, M32 and T6400 cells

Source:: ChEMBL

Protein Target:: Broad substrate specificity ATP-binding cassette transporter ABCG2

Assay data:1 Tested

AID:: 681279

Summary PubMed Citation Related BioAssays by Target

Select item 68144512.

TP_TRANSPORTER: increase in mitoxantrone intracellular accumulation (Mitoxantrone: 20 uM, GF120918: 2 uM) in KOT52 and D320 cells

Source:: ChEMBL

Protein Target:: Broad substrate specificity ATP-binding cassette transporter ABCG2

Assay data:1 Tested

AID:: 681445

Summary PubMed Citation Related BioAssays by Target

Select item 68144613.

TP_TRANSPORTER: cell accumulation in MEF3.8, M32 and T6400 cells

Source:: ChEMBL

Protein Target:: Broad substrate specificity ATP-binding cassette transporter ABCG2

Assay data:1 Tested

AID:: 681446

Summary PubMed Citation Related BioAssays by Target

Select item 68144714.

TP_TRANSPORTER: cell accumulation in KOT52 and D320 cells

Source:: ChEMBL

Protein Target:: Broad substrate specificity ATP-binding cassette transporter ABCG2

Assay data:1 Tested

AID:: 681447

Summary PubMed Citation Related BioAssays by Target

Select item 68144815.

TP_TRANSPORTER: biliary excretion

Source:: ChEMBL

Protein Target:: Broad substrate specificity ATP-binding cassette transporter ABCG2

Assay data:1 Tested

AID:: 681448

Summary PubMed Citation Related BioAssays by Target

Select item 192300516.

Substrate activity at mouse BCRP assessed as apparent permeability at 1 uM

Source:: ChEMBL

Protein Target:: Broad substrate specificity ATP-binding cassette transporter ABCG2

Assay data:9 Tested

AID:: 1923005

Summary PubMed Citation Related BioAssays by Target

Select item 68157217.

TP_TRANSPORTER: drug resistance in BCRP-expressing MEF3.8 cells

Source:: ChEMBL

Protein Target:: Broad substrate specificity ATP-binding cassette transporter ABCG2

Assay data:7 Tested

AID:: 681572

Summary PubMed Citation Related BioAssays by Target

Select item 68213918.

TP_TRANSPORTER: intestinal excretion

Source:: ChEMBL

Protein Target:: Broad substrate specificity ATP-binding cassette transporter ABCG2

Assay data:1 Tested

AID:: 682139

Summary PubMed Citation Related BioAssays by Target

Select item 105320819.

A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:788 Active, 16789 Tested

AID:: 1053208

Summary PubMed Citation

Select item 118734520.

Permeability assessed as doxycycline-induced mouse BCRP-mediated permeability from apical to basolateral side

Source:: ChEMBL

Protein Target:: Broad substrate specificity ATP-binding cassette transporter ABCG2

Assay data:3 Tested

AID:: 1187345

Summary PubMed Citation Related BioAssays by Target

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Summary (2)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Primary Screening (1)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
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BioAssays reporting BioActivity of chemical reagents
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BioAssays reporting BioActivity of RNAi reagents

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BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

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Literature Extraction (10)
BioAssays extracted from the literature
Other (20)
BioAssays deposited by other experimentalists

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