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Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
JNK3 AlphaScreen Assay
Assay data:36 Active, 11014 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Activation of JNK2/3 in mouse RAW264.7 cells assessed as phosphorylation at 50 uM after 30 mins by Western blotting analysis
Assay data:1 Active, 1 Tested
Activation of JNK2/3 in mouse RAW264.7 cells assessed as phosphorylation at 50 uM after 30 mins to 4 hrs by Western blotting analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
TLR-pathway-mouse_P3C ligand_NFkB readout
Assay data:128 Active, 756 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
TLR-pathway-mouse_R848 ligand_TNF readout
Assay data:130 Active, 756 Tested
TLR-pathway-mouse_R848 ligand_NFkB readout
Assay data:147 Active, 756 Tested
TLR-pathway-mouse_LPS ligand_NFkB readout
Assay data:137 Active, 756 Tested
TLR-pathway-mouse_P3C ligand_TNF readout
Assay data:115 Active, 756 Tested
TLR-pathway-mouse_LPS ligand_TNF readout
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
Inhibition of LPS-induced JNK phosphorylation in mouse BV-2 cells at 5 to 20 uM pretreated for 30 mins followed by LPS stimulation by Western blot analysis
Inhibition of glutamate-induced JNK activation in mouse HT-22 cells assessed as reduction in phosphorylated JNK protein level at 1 to 10 uM in presence of glutamate by Western blot analysis
Inhibition of RANKL-induced JNK phosphorylation in mouse RAW264.7 cells at 1 to 10 uM pretreated for 4 hrs prior to RANKL stimulation for 20 mins by western blot analysis
Inhibition of JNK phosphorylation in LPS stimulated mouse BV-2 cells at 1 to 10 uM preincubated with LPS for 1 hr followed by incubation with compound for 16 hrs by western blot analysis
Inhibition of JNK phosphorylation in LPS-induced mouse RAW264.7 cells at 0.75 to 3 uM preincubated for 2 hrs followed by LPS stimulation and measured after 30 mins by immunoblotting assay
Inhibition of c-Jun phosphorylation in LPS-stimulated JNK1-/- mouse embryonic fibroblast incubated for 30 mins by ELISA
Assay data:2 Active, 2 Tested
Inhibition of c-Jun phosphorylation in LPS-stimulated JNK2-/- mouse embryonic fibroblast incubated for 30 mins by ELISA
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of LPS-induced JNK phosphorylation in BALB/c mouse at 30 mg/kg administered 6 hrs after LPS stimulation by western blot analysis
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