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Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
SummaryPubMed Citation
Discovery of novel allosteric modulators of the M1 muscarinic receptor: Antagonist Secondary Assay 1
Assay data:17 Active, 1665 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
Modulation of Metabotropic Glutmate Receptor mGluR4: Human PAM Fold-Shift
Assay data:7 Active, 9 Activity ≤ 1 nM, 9 Activity ≤ 1 µM, 9 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Modulation of the Metabotropic Glutamate Receptor mGluR4: Potency at human mGluR4
Assay data:33 Active, 16 Activity ≤ 1 µM, 36 Tested
Modulation of the Metabotropic Glutamate Receptor mGluR4
Assay data:1 Active, 1 Tested
Modulation of the Metabotropic Glutamate Receptor mGluR4: Calcium Assay
Assay data:1 Active, 7 Tested
Chemical Optimization of Advanced mGlu4 Lead Candidates
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Chemical Optimization of Advanced mGlu4 Lead Candidates (human_mGlu4_potency)
Assay data:25 Active, 6 Activity ≤ 1 µM, 73 Tested
ML292 Competition in Radioligand Binding assays (Ricerca)
SummaryCompounds, ActiveRelated BioAssays by Target
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Fold shift mGlu4, mGlu7, mGlu8 using calcium mobilization
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
Modulation of the Metabotropic Glutamate Receptors mGlu7 and mGlu8: Potency at rat mGlu4/calcium
Assay data:18 Active, 1 Activity ≤ 1 µM, 23 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Fold shift mGlu4 using GIRK assays
Assay data:1 Tested
SummaryRelated BioAssays by DepositorRelated BioAssays by Target
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
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