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ML352 Eurofin Panel Assay for Choline Transporter Inhibitor (Probe Compound)
Assay data:1 Tested
SummaryRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Discovery of novel allosteric modulators of the M1 muscarinic receptor: Agonist Ancillary Activity
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Identification of Novel Modulators of Cl- dependent Transport Process via HTS: Antagonist Ancillary Profile
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Discovery of a Highly Selective in vitro and in vivo M4 Positive Allosteric Modulator: Ancillary Activity
Assay data:2 Tested
High throughput discovery of novel modulators of ROMK K+ channel activity: Ancillary Activity
Counterscreen panel assay for S1P4 antagonists: Ricerca HitProfilingScreen + CYP450
Late-stage counterscreen panel assay for S1P4 agonists: Ricerca HitProfilingScreen + CYP450
Late-stage counterscreen panel assay for GPR7 antagonists: Ricerca HitProfilingScreen + CYP450
Late-stage counterscreen panel assay for S1P4 agonists: Ricerca HitProfilingScreen + CYP450: Set 2
Late-stage counterscreen panel assay for GPR7 antagonists: Ricerca HitProfilingScreen + CYP450: Set 2
Late-stage counterscreen panel assay for S1P3 agonists: Ricerca HitProfilingScreen + CYP450
Late stage results from the probe development efforts to identify dual inhibitors of signal transducer and activator of transcription 3 (STAT3) and nuclear factor NF-kappa-B (NF-kB): Cell-based radioligand binding assay to determine the binding affinities for selected transporters, receptors, and GPCRs
Late stage results from the probe development effort to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization: Cell-based radioligand binding assay to determine the binding affinities for selected transporters, receptors, and GPCRs
ML347 Eurofin Panel Assay for BMP Inhibitor (Probe Compound)
Rat alpha1A-adrenoceptor (Adrenoceptors)
Assay data:11 Active, 11 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
ML354 Eurofin Panel Assay for PAR4 Antagonists Inhibitor (Probe Compound)
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
ML353 Eurofin Panel Assay for mGlu5 SAM Inhibitor (Probe Compound)
Late-stage counterscreen panel assay for AVPR1a antagonists: Panlabs HitProfilingScreen
Development of the First Potent, Selective and CNS penetrant M5 Negative Allosteric Modulator (NAM)
Discovery and characterization of a small molecule allosteric agonists of mas-related G-Protein coupled receptor X1 ( MrgX1)
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