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In vitro binding affinity at quisqualate binding site of quisqualate/AMPA glutamate receptors in rat brain membrane using [3H]- ]AMPA as radioligand
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity for Ionotropic glutamate receptor AMPA
Assay data:13 Active, 11 Activity ≤ 1 µM, 13 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity against Ionotropic glutamate receptor AMPA in rat brain
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Binding affinity was measured by [3H]- Ionotropic glutamate receptor AMPA binding assay.
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Binding affinity for AMPA receptor using [3H]AMPA
Assay data:3 Active, 3 Activity ≤ 1 µM, 12 Tested
Binding affinity was determined against ionotropic glutamate receptor AMPA in rat brain synaptic membranes using [3H]AMPA as radioligand
Assay data:30 Active, 14 Activity ≤ 1 µM, 52 Tested
Compound (100 uM) was evaluated for inhibition of Ionotropic glutamate receptor AMPA by using [3H]- AMPA
Assay data:1 Active, 3 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Compound was evaluated for binding affinity at Ionotropic glutamate receptor AMPA using [3H]AMPA as radioligand
Assay data:3 Active, 1 Activity ≤ 1 µM, 4 Tested
Compound was evaluated for potent antagonist intrinsic activity against Ionotropic glutamate receptor AMPA
Compound was evaluated for the inhibition of [3H]AMPA binding to Ionotropic glutamate receptor AMPA from rat brain synaptic membrane.
Assay data:8 Active, 3 Activity ≤ 1 µM, 10 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Binding affinity by measuring displacement of [3H]AMPA from Ionotropic glutamate receptor AMPA in rat cortical slice preparation
Assay data:2 Active, 1 Activity ≤ 1 µM, 7 Tested
In vitro binding affinity at quisqualate binding site of quisqualate/AMPA glutamate receptors in rat brain membrane using [3H]AMPA as radioligand
Assay data:1 Tested
Compound was tested for Ionotropic glutamate receptor AMPA antagonistic activity by measuring its ability to inhibit depolarizations induced by 40 uM AMPA in rat cortical slice preparation.
Assay data:3 Active, 5 Tested
Displacement of [3H]-AMPA from Ionotropic glutamate receptor AMPA of rat cortical membranes
Assay data:9 Active, 4 Activity ≤ 1 µM, 12 Tested
Compound was tested in vitro for binding affinity against Ionotropic glutamate receptor AMPA, using [3H]AMPA as the radioligand in rat cerebral cortical membranes.
SummaryRelated BioAssays by Target
Compound was tested or its affinity against AMPA receptor in rats
Concentration which causes 50% reduction in receptor binding affinity against Ionotropic glutamate receptor AMPA using [3H]AMPA
Assay data:2 Active, 1 Activity ≤ 1 µM, 8 Tested
Concentration which causes 50% reduction in receptor binding affinity against Ionotropic glutamate receptor AMPA using [3H]-CPPAMPA
Concentration required for 50% inhibition of [3H]AMPA binding to AMPA receptor in rat cortical slice preparation
Assay data:5 Active, 2 Activity ≤ 1 µM, 6 Tested
Evaluated in patch clamp electrophysiology study for its selectively evoked Ionotropic glutamate receptor AMPA mediated inward currents.
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