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Inhibition of IKK in TNFalpha-simulated Sprague-Dawley rat calvarial osteoblasts assessed as ratio of IkBalpha level to beta-actin level at 100 pM after 24 hrs by Western blot analysis (Rvb = 0.78 No_unit)
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of IKK in Sprague-Dawley rat calvarial osteoblasts assessed as reduction in TNFalpha-induced NFkB signaling by measuring ratio of cytosolic p65 level to beta-actin level at 10 nM after 24 hrs by Western blot analysis (Rvb = 0.99 No_unit)
Inhibition of IKK in Sprague-Dawley rat calvarial osteoblasts assessed as reduction in TNFalpha-induced NFkB signaling by measuring ratio of cytosolic p65 level to beta-actin level at 100 pM after 24 hrs by Western blot analysis (Rvb = 0.99 No_unit)
Inhibition of IKK in Sprague-Dawley rat calvarial osteoblasts assessed as reduction in TNFalpha-induced beta-catenin degradation by measuring ratio of beta-catenin level to beta-actin level at 100 pM after 24 hrs by Western blot analysis (Rvb = 0.32 No_unit)
Inhibition of IKK in Sprague-Dawley rat calvarial osteoblasts assessed as reduction in TNFalpha-induced beta-catenin degradation by measuring ratio of beta-catenin level to beta-actin level at 10 nM after 24 hrs by Western blot analysis (Rvb = 0.32 No_unit)
Inhibition of IKK in Sprague-Dawley rat calvarial osteoblasts assessed as reduction in TNFalpha-induced NFkB signaling by measuring ratio of nuclear p65 level to beta-actin level at 100 pM after 24 hrs by Western blot analysis (Rvb = 2.97 No_unit)
Inhibition of IKK in Sprague-Dawley rat calvarial osteoblasts assessed as reduction in TNFalpha-induced NFkB signaling by measuring ratio of nuclear p65 level to beta-actin level at 10 nM after 24 hrs by Western blot analysis (Rvb = 2.97 No_unit)
Inhibition of IKK in Sprague-Dawley rat calvarial osteoblasts assessed as reduction in TNFalpha-induced IkBalpha phosphorylation by measuring ratio of phosphorylated IkBalpha level to beta-actin level at 100 pM after 24 hrs by Western blot analysis (Rvb = 2.32 No_unit)
Inhibition of IKK in Sprague-Dawley rat calvarial osteoblasts assessed as reduction in TNFalpha-induced IkBalpha phosphorylation by measuring ratio of phosphorylated IkBalpha level to beta-actin level at 10 nM after 24 hrs by Western blot analysis (Rvb = 2.32 No_unit)
Inhibition of IKK in Sprague-Dawley rat calvarial osteoblasts assessed as reduction in TNFalpha-induced NFkB nuclear translocation at 10 nM after 24 hrs by immunofluorescence assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of IKK in TNFalpha-simulated Sprague-Dawley rat calvarial osteoblasts assessed as ratio of IkBalpha level to beta-actin level at 10 nM after 24 hrs by Western blot analysis (Rvb = 0.78 No_unit)
Inhibition of IKK in TNFalpha-simulated Sprague-Dawley rat calvarial osteoblasts assessed as ratio of Bcl2 level to beta-actin level at 100 pM after 24 hrs by Western blot analysis (Rvb = 0.77 No_unit)
Inhibition of IKK in TNFalpha-simulated Sprague-Dawley rat calvarial osteoblasts assessed as ratio of Bcl2 level to beta-actin level at 10 nM after 24 hrs by Western blot analysis (Rvb = 0.77 No_unit)
Inhibition of IKK in TNFalpha-simulated Sprague-Dawley rat calvarial osteoblasts assessed as ratio of Bcl-xL level to beta-actin level at 100 pM after 24 hrs by Western blot analysis (Rvb = 0.69 No_unit)
Inhibition of IKK in TNFalpha-simulated Sprague-Dawley rat calvarial osteoblasts assessed as ratio of Bcl-xL level to beta-actin level at 10 nM after 24 hrs by Western blot analysis (Rvb = 0.69 No_unit)
Inhibition of IKK in TNFalpha-simulated Sprague-Dawley rat calvarial osteoblasts assessed as ratio of Bax level to beta-actin level at 100 pM after 24 hrs by Western blot analysis (Rvb = 1.25 No_unit)
Inhibition of IKK in TNFalpha-simulated Sprague-Dawley rat calvarial osteoblasts assessed as ratio of Bax level to beta-actin level at 10 nM after 24 hrs by Western blot analysis (Rvb = 1.25 No_unit)
Inhibition of IKK in Sprague-Dawley rat calvarial osteoblasts assessed as reduction in TNFalpha-induced NFkB nuclear translocation at 100 pM after 24 hrs by immunofluorescence assay
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