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A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Induction of Nur77-SRC2 interaction in HEK293T cells by GST-pull-down assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Induction of Nur77-SRC3 interaction in HEK293T cells by GST-pull-down assay
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Induction of SRC2-enhanced Nur77 transactivational activity in human BGC823 cells after 12 hrs by luciferase/beta-galactosidase reporter assay
Induction of SRC1-enhanced Nur77 transactivational activity in human BGC823 cells after 12 hrs by luciferase/beta-galactosidase reporter assay
Agonist activity at Nur77 expressed in human gastric cancer BGC823 assessed as transactivation in presence of siRNA against Nur77
Agonist activity at Nur77 expressed in human BGC823 cells assessed as Nr4a1mRNA expression by real-time PCR
Late stage assay provider results from the probe development effort to identify inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
Effect on GFRP1(NR4A1) dependent reporter activity in HEK293 cells at 20 uM
Assay data:2 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Summary
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Induction of Nur77-SRC1 interaction in human 293T cells by GST-pull-down assay
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
Binding affinity to human recombinant N-terminal His6-tagged NR4A1 LBD expressed in Escherichia coli BL21 by isothermal titration calorimetry
Binding affinity to human recombinant N-terminal His6-tagged NR4A1 LBD expressed in Escherichia coli BL21 at 50 uM by NMR spectroscopy
Assay data:1 Active, 2 Tested
Binding affinity to human recombinant N-terminal His6-tagged NR4A1 LBD expressed in Escherichia coli BL21 at 100 uM by NMR spectroscopy
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