Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
SummaryPubMed Citation
Allosteric regulation of recombinant HSC70 (unknown origin) ATPase activity assessed as increase in ADP production at 10 uM after 10 mins in presence of HCV wild type poly U/UC RNA by HPLC analysis
Assay data:11 Active, 11 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to human truncated HSC70 NBD (1 to 381 residues) by SPR analysis
Assay data:11 Active, 5 Activity ≤ 1 µM, 20 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
Inhibition of HSC70 (unknown origin)
Assay data:5 Tested
SummaryPubMed CitationRelated BioAssays by Target
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
Summary
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
Binding affinity to human HSC70 after 3 hrs by ELISA
Assay data:13 Active, 3 Activity ≤ 1 µM, 14 Tested
Displacement of N6-(6-amino)hexyl-ATP ATTO-590-ATP from HSC70 (unknown origin) after 18 hrs by fluorescence polarization assay
Assay data:4 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Induction of HSC70 chaperone activity in human Huh-luc/neo-ET cells assessed as reduction in HCV RNA NS5A protein expression at 6 nM after 24 hrs
Assay data:1 Active, 1 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
Binding affinity to Hsp70 nucleotide binding domain in human BT474 cells
Assay data:1 Tested
Binding affinity to human Hsc70 by isothermal calorimetry assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Induction of annexin-2-mediated cytotoxicity in human MCF10A cells assessed as cell morphology at 4 uM after 2 hrs by scanning electron microscopy
Assay data:2 Tested
Binding affinity to HSC70 EEVD domain by mass spectroscopy
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on