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Inhibition of IleRS
Assay data:24 Tested
SummaryPubMed CitationRelated BioAssays by Target
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
Inhibitory concentration against isoleucyl-tRNA synthetase was determined by measuring decrease of the aminoacylation product [3H]- isoleucyl tRNA of Escherichia coli
Assay data:1 Tested
Inhibition of Escherichia coli isoleucyl-tRNA synthetase
Assay data:9 Active, 9 Activity ≤ 1 µM, 13 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Compound was evaluated for inhibitory activity against Isoleucyl-tRNA synthetase
Assay data:5 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 6 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibitory activity against Escherichia coli Isoleucyl-tRNA synthetase was determined
Assay data:5 Active, 3 Activity ≤ 1 µM, 8 Tested
Compound tested for the inhibition of human isoleucyl-tRNA synthetase
Assay data:9 Active, 8 Activity ≤ 1 µM, 9 Tested
Assay data:1 Active, 11 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of [3H]isoleucyl incorporation by Escherichia coli isoleucyl-tRNA synthetase (IleRS)
Assay data:10 Tested
In vitro antibacterial activity against isoleucyl-tRNA synthetase from Haemophilus influenzae Q1
Assay data:4 Tested
In vitro antibacterial activity against isoleucyl-tRNA synthetase from Moraxella catarrhalis 1502
In vitro antibacterial activity against isoleucyl-tRNA synthetase from Streptococcus pneumoniae PU7
In vitro antibacterial activity against isoleucyl-tRNA synthetase from Streptococcus pyogenes CN10
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
SummaryPubMed Citation
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
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