BioAssay by Target (List) for Gene (Select 3742) - PubChem BioAssay - NCBI

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Select item 6010641.

Inhibition of human recombinant Kv channel at 10 uM by radioligand binding assay

Source:: ChEMBL

Protein Targets:: Potassium voltage-gated channel subfamily A member 1; ...
Total:: 40

Assay data:2 Active, 5 Tested

AID:: 601064

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 11172812.

A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:555 Active, 64752 Tested

AID:: 1117281

Summary PubMed Citation

Select item 7535653.

Inhibition of human Kv channel at 1 uM relative to control

Source:: ChEMBL

Protein Targets:: Potassium voltage-gated channel subfamily A member 1; ...
Total:: 40

Assay data:1 Tested

AID:: 753565

Summary PubMed Citation Related BioAssays by Target

Select item 7522734.

Binding affinity to voltage-gated potassium channel (unknown origin) at 10 uM by radioligand displacement assay relative to control

Source:: ChEMBL

Protein Targets:: Potassium voltage-gated channel subfamily A member 1; ...
Total:: 40

Assay data:1 Tested

AID:: 752273

Summary PubMed Citation Related BioAssays by Target

Select item 7434545.

RNAi screen for vorinostat resistance genes - Primary Screen

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:450 Active, 18118 Tested

AID:: 743454

Summary PubMed Citation

Select item 7431216.

Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:167 Active, 26449 Tested

AID:: 743121

Select item 6518117.

Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:9227 Active, 64752 Tested

AID:: 651811

Summary PubMed Citation

Select item 6518108.

Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:826 Active, 18119 Tested

AID:: 651810

Summary PubMed Citation

Select item 6240999.

An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Assay data:497 Active, 21019 Tested

AID:: 624099

Summary PubMed Citation

Select item 111735710.

InfectX: Pathogen infection siRNA screens

Source:: InfectX Consortium

Assay data:115372 Tested

AID:: 1117357

Summary PubMed Citation

Select item 31363311.

Blockade of Kv1.6 channel over-expressed in CHO cells assessed as inhibition of delayed rectifying K+ current at 10 uM

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily A member 6

Assay data:1 Tested

AID:: 313633

Summary PubMed Citation Related BioAssays by Target

Select item 30544212.

Binding affinity for potassium channel at 1 uM

Source:: ChEMBL

Protein Targets:: Potassium voltage-gated channel subfamily A member 1; ...
Total:: 40

Assay data:3 Tested

AID:: 305442

Summary PubMed Citation Related BioAssays by Target

Select item 27531813.

Inhibition of voltage-gated potassium channel

Source:: ChEMBL

Protein Targets:: Potassium voltage-gated channel subfamily A member 1; ...
Total:: 40

Assay data:6 Tested

AID:: 275318

Summary PubMed Citation Related BioAssays by Target

Select item 9561914.

Blockade of peak K+ currents against Kv1.6 gene; not determined

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily A member 6

Assay data:1 Tested

AID:: 95619

Summary PubMed Citation Related BioAssays by Target

Select item 9561815.

Blockade of peak K+ currents against Kv1.6 gene; Not determined

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily A member 6

Assay data:3 Tested

AID:: 95618

Summary PubMed Citation Related BioAssays by Target

Select item 9561716.

Blockade of peak K+ currents against Kv1.6 gene

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily A member 6

Assay data:1 Tested

AID:: 95617

Summary PubMed Citation Related BioAssays by Target

Select item 190417.

siRNA Circadian Assay

Source:: The Genomics Institute of the Novartis Research Foundation (GNF)

Assay data:527 Active, 33364 Tested

AID:: 1904

Summary PubMed Citation Related BioAssays by Depositor

Select item 134665718.

Human Kv1.6 (Voltage-gated potassium channels)

Source:: IUPHAR/BPS Guide to PHARMACOLOGY

Protein Target:: potassium voltage-gated channel subfamily A member 6

Assay data:4 Active, 4 Tested

AID:: 1346657

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 178839019.

K+ channel (volt-dependent) CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Potassium voltage-gated channel subfamily A member 1; ...
Total:: 40

Assay data:1 Tested

AID:: 1788390

Summary Related BioAssays by Target

Select item 178831420.

K+ channel (Volt-dependent) Ligand binding assay

Source:: ChEMBL

Protein Targets:: Potassium voltage-gated channel subfamily A member 1; ...
Total:: 40

Assay data:1 Tested

AID:: 1788314

Summary Related BioAssays by Target

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Target

Proteins (1)
BioAssays with protein sequences specified as targets
RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (3)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 µM (1)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (3)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (9)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (21)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (13)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (17)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (16)
BioAssays deposited by other experimentalists

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