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Dose Response of round 1 SAR compounds for GTPase inhibitor project tested by multiplex of eight GTPase proteins under the condition of Mg Buffer, non-chelator buffer
Assay data:11 Active, 26 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
Inhibition of RhoA/C-mediated LPA-induced DNA synthesis in human PC3 cells
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of RhoA/C-mediated LPA-induced DNA synthesis in RhoC-expressing human A375M2 at < 1 uM
Inhibition of RhoA/C-mediated LPA-induced DNA synthesis in RhoC-expressing human SK-MEL-147 at < 1 uM
Inhibition of RhoA/C-mediated LPA-induced DNA synthesis in human A375 cells expressing low level of RhoC at < 1 uM
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of RhoA/C-mediated transcriptional response in human PC3 cells by serum response factor-luciferase reporter gene assay
Assay data:14 Active, 35 Tested
Inhibition of RhoA/C-mediated transcriptional response in human PC3 cells at 10 uM by serum response factor-luciferase reporter gene assay
Assay data:25 Tested
Inhibition of RhoA/C-mediated transcriptional response in human PC3 cells at 100 uM by serum response factor-luciferase reporter gene assay
Inhibition of RhoA/C-mediated pRL-thymidin kinase gene expression in human PC3 at 10 uM by renilla luciferase reporter gene assay
Inhibition of RhoA/C-mediated pRL-thymidin kinase gene expression in human PC3 at 100 uM by renilla luciferase reporter gene assay
Inhibition of RhoA/C-dependent invasion of human PC3 cells
Dose Response of round 1 SAR compounds for Cdc42 probe extension project tested by multiplex of eight GTPase proteins under the condition of Mg Buffer, non-chelator buffer
Assay data:5 Active, 5 Tested
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Dose Response of round 2 SAR compounds for GTPase inhibitor project tested by multiplex of eight GTPase proteins under the condition of Mg Buffer, non-chelator buffer
Assay data:23 Active, 25 Tested
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
SummaryPubMed Citation
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
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