BioAssay by Target (List) for Gene (Select 4324) - PubChem BioAssay - NCBI

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Select item 6240991.

An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Assay data:497 Active, 21019 Tested

AID:: 624099

Summary PubMed Citation

Select item 19042.

siRNA Circadian Assay

Source:: The Genomics Institute of the Novartis Research Foundation (GNF)

Assay data:527 Active, 33364 Tested

AID:: 1904

Summary PubMed Citation Related BioAssays by Depositor

Select item 1095683.

Affinity for Matrix metalloprotease-15 (MMP-15)

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-15

Assay data:1 Active, 1 Tested

AID:: 109568

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 1095694.

Inhibition of matrix metalloprotease-15

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-15

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 109569

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 1095705.

Inhibition of matrix metalloprotease-15

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-15

Assay data:1 Active, 4 Tested

AID:: 109570

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 1095716.

Inhibition of matrix metalloprotease-15 (MMP-15)

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-15

Assay data:13 Active, 11 Activity ≤ 1 µM, 13 Tested

AID:: 109571

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 2594627.

Inhibitory activity against MMP15

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-15

Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 259462

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 2594708.

Inhibitory activity against MMP15 upto 50uM

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-15

Assay data:5 Tested

AID:: 259470

Summary PubMed Citation Related BioAssays by Target

Select item 2647289.

Binding affinity to MMP15

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-15

Assay data:2 Tested

AID:: 264728

Summary PubMed Citation Related BioAssays by Target

Select item 29906510.

Inhibition of MMP15

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-15

Assay data:1 Tested

AID:: 299065

Summary PubMed Citation Related BioAssays by Target

Select item 31434611.

Inhibition of MMP15

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-15

Assay data:3 Tested

AID:: 314346

Summary PubMed Citation Related BioAssays by Target

Select item 31521912.

Binding affinity to MMP15

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-15

Assay data:1 Tested

AID:: 315219

Summary PubMed Citation Related BioAssays by Target

Select item 31584413.

Inhibition of MMP15

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-15

Assay data:1 Tested

AID:: 315844

Summary PubMed Citation Related BioAssays by Target

Select item 34941514.

Inhibition of MMP15

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-15

Assay data:2 Active, 7 Tested

AID:: 349415

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 37088415.

Inhibition of human recombinant MMP15 at 200 uM by HxBPyne probe-based competitive activity based protein profiling assay in presence of 5 uM HxBpane competitor

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-15

Assay data:1 Active, 3 Tested

AID:: 370884

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 45417616.

Inhibition of MMP15

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-15

Assay data:1 Tested

AID:: 454176

Summary PubMed Citation Related BioAssays by Target

Select item 186395017.

Inhibition of MMP-15 (unknown origin) expressed in Escherichia coli BL21(DE3) and measured for 2 mins by enzymatic assay

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-15

Assay data:1 Active, 1 Tested

AID:: 1863950

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 64920018.

Inhibition of human MMP15

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-15

Assay data:1 Tested

AID:: 649200

Summary PubMed Citation Related BioAssays by Target

Select item 65181019.

Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:826 Active, 18119 Tested

AID:: 651810

Summary PubMed Citation

Select item 65181120.

Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:9227 Active, 64752 Tested

AID:: 651811

Summary PubMed Citation

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Target

Proteins (1)
BioAssays with protein sequences specified as targets
RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (10)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 µM (3)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (15)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (9)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (18)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (13)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (18)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (12)
BioAssays deposited by other experimentalists

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