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Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assay relative to 30 ng/mL thrombopoietin
Assay data:22 Tested
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at human recombinant TPO receptor expressed in mouse BaF3 cells after 24 hrs
Assay data:3 Active, 5 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at human recombinant TPO receptor expressed in mouse BaF3 cells at 300 nM after 24 hrs relative to TPO
Assay data:25 Tested
Agonist activity at human recombinant TPO receptor expressed in mouse BaF3 cells at 150 nM after 24 hrs relative to TPO
Agonist activity at human TPO receptor expressed in rat BaF3 cells
Assay data:15 Active, 19 Activity ≤ 1 µM, 19 Tested
Agonist activity at human thrombopoietin receptor transfected in mouse BAF3 cells assessed as stimulation of beta lactamase activity incubated in dark up to 1 hr
Assay data:17 Active, 18 Activity ≤ 1 µM, 20 Tested
Agonist activity at human thrombopoietin receptor in Ba/F3 cells assessed as activation of Stat5 response element-driven reporter gene expression relative to 30 ng/mL thrombopoietin
Assay data:30 Tested
Agonist activity at human thrombopoietin receptor in Ba/F3 cells assessed as activation of Stat5 response element-driven reporter gene expression
Assay data:30 Active, 25 Activity ≤ 1 µM, 37 Tested
Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells in presence of 1 mM Zinc by kinase activation based reporter gene assay relative to 30 ng/mL thrombopoietin
Assay data:5 Tested
Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells in presence of 1 mM Zinc by kinase activation based reporter gene assay
Inhibition of human TPOR expressed in human BaF3 cells
Assay data:9 Active, 9 Activity ≤ 1 µM, 9 Tested
Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assay
Assay data:20 Active, 19 Activity ≤ 1 µM, 22 Tested
Agonist activity at TPO receptor at 10 uM
Agonist activity at TPO receptor
Assay data:40 Active, 31 Activity ≤ 1 µM, 44 Tested
Agonist activity at human TPOr expressed in BaF3 cells by reporter assay
Assay data:85 Active, 60 Activity ≤ 1 µM, 112 Tested
Agonist activity as induced proliferation in Ba/F3-hTpoR murine lymphocyte expressing human TPOR
Assay data:10 Active, 5 Activity ≤ 1 µM, 14 Tested
Thrombopoietin luciferase activity in BAF-3 cells
Assay data:63 Tested
Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells
Assay data:43 Active, 23 Activity ≤ 1 µM, 45 Tested
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
SummaryPubMed Citation
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