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Inhibition of [14C]aminopyrine (AP) accumulation stimulated by dibutyryl cyclic AMP in isolated rabbit parietal cells
Assay data:9 Active, 5 Activity ≤ 1 µM, 12 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
In vitro inhibitory activity against H+/K+ ATPase prepared from canine fundic mucosa
Assay data:28 Active, 8 Activity ≤ 1 µM, 44 Tested
Inhibitory activity of gastric proton-pump enzyme H+/K+ ATPase was determined at 50 uM
Assay data:2 Active, 5 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibitory activity against dog gastric proton-pump enzyme H+/K+ ATPase
Assay data:58 Active, 9 Activity ≤ 1 µM, 85 Tested
The compound was tested in vivo for inhibition of gastric proton-pump enzyme H+/K+ ATPase
Assay data:4 Active, 3 Activity ≤ 1 µM, 4 Tested
Percent inhibition of gastric proton-pump enzyme H+/K+ ATPase was determined at 10 uM
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Percent inhibition of gastric proton-pump enzyme H+/K+ ATPase was determined at 50 uM
Assay data:130 Tested
Compound was tested in vitro for H+/K+ ATPase activity in rabbit stomach preparations
Assay data:6 Active, 17 Tested
Inhibition of H+/K+ ATPase as reduced acid formation in rabbit gastric glands
Assay data:10 Active, 7 Activity ≤ 1 µM, 13 Tested
Inhibition of H+/K+ ATPase was evaluated by its ability to inhibit acid formation in rabbit gastric glands; Inactive
Evaluated for the inhibition of H+/K+ ATPase enzyme from fundic mucosa of white rabbits at 100 uM
Assay data:1 Tested
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach.
Assay data:22 Active, 9 Activity ≤ 1 µM, 26 Tested
Inhibition of H+/K+ ATPase activity in buffered solution (pH 7.4)
Assay data:1 Active, 6 Tested
Inhibition of H+/K+ ATPase activity in buffered solution (pH 7.4) at concentration 400 mM
Assay data:15 Tested
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Percent inhibition of [14C]aminopyrine (AP) accumulation in dibutyryl cAMP stimulated rbbit parietal cells at 10 uM
Assay data:18 Tested
Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by dibutyryl cyclic adenosine 3', 5' -monophosphate (dcAMP)
Assay data:54 Active, 43 Activity ≤ 1 µM, 55 Tested
Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamine
Assay data:57 Active, 48 Activity ≤ 1 µM, 57 Tested
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
SummaryPubMed Citation
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